Pairwise statistical comparison of the magnitude metric revealed a trend towards significance between placebo/moderate doses (paired t-test: p = 0.061) in the go-only blocks, with low alcohol dose showing a larger magnitude metric than placebo (Supplementary Fig. 5 a).
The cumulative survival rates in the frailty group were lower than those in the non-frailty group, although the difference was marginally significant ( p = 0.061).
We detected a significant association between PD patients with depression and severe constipation (grade 3) (OR 5.81; 95% CI 1.24–27.29, p = 0.026, adjusted for age and gender), but a marginal significance after being adjusted for age, gender and UPDRS part 3 (OR 4.46, 95% CI 0.93–21.33; p = 0.061).
Focusing on the interaction, post-hoc tests showed a significant difference between the first 5 trials and the subsequent five for the SOG group (p = 0.007), and marginally significant difference for the OG group (p = 0.061).
The vehicle-treated group demonstrates a strong trend towards the net loss of spines over the course of our study, reaching a near-significant level by 132 h (p = 0.061 for 0–132 h, see Table 2 ).
The main effect of field approached significance, F (2, 24) = 3.16, p = 0.061, partial ƞ 2 = 0.21, whereby full fields ( M = 16.95%, SD = 6.58) and fields >10° ( M = 15.55%, SD = 5.22) had numerically lower thresholds than the 0–10° field condition ( M = 22.24%, SD = 10.54) (Fig. 1C,D ).
However, the difference was statistically significant with the visual JND (bootstrap mean difference: −2.1 ± 0.98, p = 0.002) and only close to significance with the somatosensory JND ( − 1.8 ± 0.7, p = 0.061).
Individuals surviving pond drying experienced a marginally non-significant increase in the GSH/GSSG ratio (df = 1, 99; χ 2 = 3.499, p = 0.061), whereas those that survived predators did not alter their GSH/GSSG ratio at all (df = 1, 99; χ 2 = 2.168, p = 0.140; Table 1 ).
Specifically, the comparison between BMI and ceramide approached significance (Z = 1.87, p = 0.061), while comparisons with TG (Z = 0.31, p = 0.76) and DG (Z = 0.49, p = 0.62) were non-significant.
However, when ileum mucosa samples were specifically analysed, differences in richness among sampling time points were close to significance (Shannon index; p = 0.061).
Finally, there was a trend towards significance for the 3-way interaction including the quadratic component (F(1,13) = 3.54, p = 0.061), which could be explained by a larger active vs. sham decrease of the (negative) quadratic coefficient for rhythmic than for sham stimulation (p < 0.05; CI = [−0.26 −0.03]; d = 0.76; B U[−0.10 0.24] = 2.26; both active vs. sham differences being significant when tested separately, p < 0.01; for rhythmic: d = 1.34; for random: d = 1.14).
Compared with one tumor lesion, two lesions were significant unfavorable prognosticator of OS (HR, 3.148; 95% CI, 1.747–5.672; p < 0.001), three lesions also showed an unfavorable trend albeit without statistical significance (HR, 2.116; 95% CI, 0.967–4.633; p = 0.061).
The assistants’ ratings indicated a reduction in hypertonia across the twelve sessions which only approached significance according to the linear mixed model analysis ( p = 0.061).
In a multivariate Cox regression model, high levels of total Δ133p53 were found to be an independent prognosticator for improved overall survival (HR = 0.422, p = 0.018, 95% CI: 0.207–0.861) and reached borderline significance for progression-free survival (HR = 0.569, p = 0.061, 95% CI: 0.315–1.027).
However, higher zonulin levels showed a positive trend towards increased duodenal bacterial load (r s = 0.36, p = 0.061) and zonulin correlations also extended to obesity associated parameters such as body mass index (r s = 0.65, p = 0.01E−02), waist circumference (r s = 0.47, p = 0.009), and hip circumference (r s = 0.53, p = 0.003) (Supplementary Table 3 ).
CD15 + MPO − TANs also correlated inversely with skin metastasis ( P = 0.020), a trend was seen for association between CD15 − MPO + (MPO + ) cells and lung metastasis ( P = 0.059; Table 3 ), while CD15 + MPO + TANs showed a negative trend towards correlating with bone metastasis ( P = 0.061).
CB exposure caused a dose-dependent decrease in viability within the alveolar triple cell co-culture, approaching significance at the highest CB concentration ( p = 0.061) (Fig. 5 D and E).