“reached borderline significance”

Limitations at the study level may include a lack of reporting quality control steps, reporting of variants within linkage disequilibrium, small sample size, and a lack of reporting variants that failed to reach genome-wide significance ( p < 5 × 10 −8 ) but may have reached borderline significance levels ( p < 10 −7 ).

One association reached borderline significance (p = 6.41∙10 −7 ) when using the RAVA-FIRST strategy, i.e. with CADD regions and the corresponding ACS filtering.

The analyses of the BIS subscales showed that this differential effect was particularly attributable to motor impulsivity (i.e., acting without thinking), where the group*time interaction reached borderline significance ( p = .066, see also Table S4 in Supplement) and post hoc tests indicated a highly significant improvement in the active group ( p = .005) but no significant change in the sham group ( p = .58).

Patients with EAD reported more depressive symptoms at endpoint as measured on BDI, though when adjusted for gender this difference only reached borderline significance (p = 0.008).

For the automated measurements, night-time IOP was significantly lower than daytime IOP on day 1 and reached borderline significance on day 2 (Δ IOP=2.9 mm Hg, p=0.01 and Δ IOP=2.9 mm Hg, p=0.06, respectively).

The between-subjects effects of EPA status were significant for the second trial (T2) ( F (2,100) = 6.096, p = 0.003) and reached borderline significance for T3 ( F (2,100) = 4.825, p = 0.010) after Bonferroni correction of the significance level ( p < 0.01).

Of the associations between QTs and SNPs which showed consistent trans eQTL evidence (for diastolic blood pressure, triglycerides, crp and height), only one association, between height and rs1482455 (tagging eQTL SNP rs716618 with r 2 = 0.84) reached borderline significance (p = 0.01) in a meta-analysis of 5,828 females.

Second, IL-5 levels have been investigated only in a few studies, and one of these studies described an increase in IL5 levels for patients with advanced disease that reached borderline significance ( p = 0.017) and showed a large overlap between patients with advanced and less severe CRS [ 24 ] Third, as indicated in Table 1 the levels of Ang-1, Ang-2 and vascular endothelial growth factor (VEGF) are altered in patients advanced CRS; these effects alterations are not caused by a difference in

Position 301 (PNLG) reached borderline significance in the complete scan of Env when testing for an association between the preservation or loss of specific PNLGs and the b12 neutralization (p = 0.019, q = 0.30, OR = 0.23).

AKT1S1 , SCG5 , CEACAM1 , and ALOX12B reached borderline significance between the CR and PD groups ( p = 0.022 to 0.09).

The Shock Index (SI) reached borderline significance within the 1.00–1.39 range (OR = 1.182, P = 0.023).

TSH reached borderline significance (OR 1.012; 95% CI 1.002-1.023; p = 0.024).

The difference between the best p gain and fixed p gain{exc,inh} settings was not significant ( p = 0.324, Wilcoxon signed-rank test), and the small decreased observed in the best p gain{exc,inh} setting relative to the fixed p gain{exc,inh} and best p gain settings reached borderline significance ( p = 0.030 and p = 0.003, respectively, Wilcoxon signed-rank tests).

Interaction between alcohol consumption and rs13181 reached borderline significance for decreased risk of lung cancer (OR = 0.25, p = 0.03, p-interaction: 0.06).

Although the Hosmer–Lemeshow test reached borderline significance ( p = 0.034), graphical calibration indicated acceptable agreement between predicted and observed probabilities (data not shown).

Finally, we did not do any adjustment for the p -value in the multiple tests that we included in our analysis as we preferred not to miss important findings; however, only two of the comparisons that we have made (the K2 value of the IOLMaster 700 versus TK2 and EKR K1-2 mm versus TK1) reached borderline significance ( p = 0.04).

The repriming pressure with air was higher in old lots (30.5 mm Hg) than new lots (23.8 mm Hg), a difference that reached borderline significance ( P = 0.04), whereas there was no significant difference in other comparisons.

This reached borderline significance for children classified as having SRD plus CM (p = 0.04) [unadjusted: p = 0.19].

Although our results on low penetrance families segregating other LP alleles reached borderline significance (p = 0.041), we propose this hypothesis as a general mechanism to explain disease occurrence in the context of low penetrance Rb.

Although the frequencies were different (10.6% controls, 17.7% MO, 16.4% MA), they only reached borderline significance in MO (P = 0.042), while no significant differences were found in MA (P = 0.12).

Men who reported past HIV testing were not more or less likely to have prevalent HIV infection, but men who reported testing and not returning for HIV test results were nearly twice as likely to be HIV infected on presentation to the clinic and this association reached borderline significance, p = 0.042.

Among inflammatory indices, NLR, SII, SIRI, and PIV values were significantly higher in PGDM compared to controls ( p -values ranging from 0.01 to 0.03), while PLR, MLR, and MII-1 to MII-3 showed no statistically significant differences across all groups, with the exception of MII-3 which reached borderline significance ( p = 0.043) (Table 3 ).

In addition, the PPG pulse amplitude ratio at 30–60 s interval decreased with total cholesterol, but this association only reached borderline significance (p=0.045; table 2 ).

For VEDO we added analysis of the disease extension, where E1/E2 versus E3/E4 reached borderline significance when added to the linear mixed model being positively associated with higher F-CPT ( β 1.915, 95% CI 0.1696–3.6621, p = 0.045).

PED reduction reached borderline significance ( p = 0.0455).