Results In primary care, there was a negative trend in fluoroquinolone item dispensing, with a 4.2% reduction in items dispensed per year (95% CI −5.2% to −3.3%; P = 6 × 10 −13 ).
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p=0.09
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At the national level, it also showed a negative trend between prevalence and SDI (R = −0.33, p = 2 × 10 −6 ) ( Supplementary Figure S6A ).
Based on the observed data, a negative trend of four species lost per census (per 5 years) was observed ( figure 4 d ; average p = 2 × 10 −5 from bootstrap least-squares linear regression).
Females from 1999 to 2008 showed a negative trend (APC − 0.9298%/year, 95% CI: -1.2649 to -0.5937, P = 0.000038), changing into an upward trend shift from 2008 to 2018 (APC 0.9979%/year, 95% CI: 0.6830 to 1.3138, P = 0.000008), continuing through 2018 up until 2021 (APC 8.0298%/year, 95% CI: 4.7989 to 11.3602, P = 0.000085) (Fig. 3 C).
A negative trend was revealed between the ISSs and incidence of 14-day rehospitalization with new tSCI diagnosis ( P < 0.0001).
The national average of LOS for this period was 11.4 ± 1.2 days, showing a negative trend over time (Y = −0.27X + 567.5; P < 0.0001).
Overall, in the investigated period, the results showed a negative trend (average Annual Percentage Change (AAPC) of −1.931, p < 0.0001).
Linear test for trend confirmed a dose–response pattern with a positive trend for both maternal income for narrow AN ( p < .03) and paternal income for narrow and broad AN (both p < .0001), but a negative trend for both maternal and paternal income for MDD (both p < .0001).
Results of statistical analysis The Jockheere-Terpstra Test revealed a negative trend (Z = -9.1568, p<0.0001), indicating that more aggressive metastatic cancer had the lowest protein expression scores, while Gleason scores of 3 or 4/5 had higher protein expression scores.
We detected a negative trend between residential proximity to banana plantation (ln-meters) and lnETU concentrations: β = –0.08 (95% CI: –0.11, –0.05) ( p < 0.0001) (see Supplemental Material, Figure S1).
Regarding the actual monthly evapotranspiration, a negative trend was observed that represented a reduction of 42.1 mm during the study period ( p -value = 0.0001, for Mann-Kendall test) ( Figure 4 D).
As expected, a negative trend between both variables is evident in the two groups ( Fig. 4b ), with individual seed mass decreasing linearly with increasing fruit seediness ( F = 126.0, P <0.0001, d.f. = 3, 87).
The mean age in the total cohort was 59.69 ± 13.74 years, and the sub-cohort of younger participants (50.01 ± 13.34) in the category with the highest level of education showed a negative trend ( p = 0.0001).
Using a meta-regression model (Section 2, Model 1) where publication date is the sole moderator, we find that the date of publication demonstrates a negative trend that accounts for 91.8% of the heterogeneity between studies (B = −0.166 [−0.254, −0.078], Q m = 13.72, p = 0.0002, k ES = 14 effect sizes, n = 206, τ resid = 0.110, see Figure 2A and Table 3 ).
In the nonadjusted model, WWI showed a negative trend ( β = −0.02, p =0.0003).
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In comparing the percentage of responses between “currently” and “once adapted”, there was a positive trend in all of the % agrees, and a negative trend in all of the % disagrees (p<0.0005).
The declining German research output negatively correlated with increasing numbers of specialist pediatric surgeons for total (τ = −0.54; P = 0.0156) and manuscripts per surgeon (τ = −0.79; P = 0.0001), resulting in a negative trend over time (χ 2 = 11.845, P = 0.0006).
At 24 h, with the HFNC failure group showing a negative trend compared to the HFNC success group (-1.00 ± 2.64 vs. 2.91 ± 3.73, p = 0.001).
Glucose consumption and lactate accumulation were strongly correlated with a negative trend in viability seen between 12°C and 37°C ( r = -0.784 and -0.700, respectively; P < 0.001 in both cases).
When all open surgical procedures were analyzed, normalized service utilization demonstrated a negative trend over time (τ = −1.0, P < .001, Fig. 2 ).
The effect of number of repetitions differed between the series, with a negative trend in the first series and a neutral slope in the second and third series (main effect for repetition number: OR = 0.98, 95% CI [0.96, 0.99], p < 0.001; interaction between second series and repetition number: OR = 1.02, 95% CI [1.00, 1.04], p = 0.018; interaction between third series and repetition number: OR = 1.02, 95% CI [1.00, 1.04], p = 0.044).
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Psychological distress correlated significantly in a positive trend with emotional distress and in a negative trend with resilience ( p < 0.001) (Figure 6 ).
Moreover, a negative trend was found among four groups regarding total lymphocytes, CD4 + , CD8 + and B lymphocytes ( p < 0.001, p < 0.005, p < 0.000, p < 0.044, respectively).
The Poisson mixed effect model for incidence (Table 7 ) shows a negative trend of the incidence of T2DM, all other things being equal (log(IRR)=−0.18, p < 0.001).
Relative humidity had a negative trend of −3.4×10 −3 (p<0.001) based on MERRA dataset and −6.67×10 −4 (p<0.1) based on meteorology observations ( Figure 2C ).