The prevalence of simple MND (81.3%) was significantly higher in the ASD group than in the control group ( p < 0.0001); interestingly, in children with ASD, complex MND (15.6%) occurred more frequently than in non ASD children (0%), with a difference that approached significance ( p = 0.053) ( Table 1 ).
However, Group 1 patients showed a trend toward longer operative times (580.07 ± 126.84 vs. 481.25 ± 119.29 min, p = 0.053), which may reflect the increased technical complexity of operating on previously dissected tissue.
The 50–100 Hz group also showed a marginally significant difference relative to the reference group (β = 0.424, p = 0.053).
Within-group longitudinal analyses across 2 time points (by the Wilcoxon signed-rank test) confirmed stable over time TNF-α levels in the evolocumab group (all p > 0.1), whereas in the control group a borderline significant increase was observed at 72 h vs. baseline ( p = 0.053) ( Supplementary Table S2 ).
This difference was borderline non-significant ( p = 0.053).
Infections diagnosed within 3 months from initial diagnosis showed a trend toward poorer outcomes (HR = 0.6, 95% CI: 0.3–1.0, p = 0.053), although this did not reach conventional statistical significance.
In contrast, in the usual care group, the E/e′ ratio increment during exercise increased slightly from 2.9 to 3.0 ( p = 0.78), resulting in nearly significant between-group differences ( p = 0.053, Table 3 , Figure 4 a).
TAPSE/PASP remained significantly associated with a high risk of events using Cox univariate analysis (HR: 0.046; 95% CI [0.004–0.45], p = 0.009) but at the limit of significance in the clinical multivariate model (HR: 0.045; 95% CI [0.001–1.02], p = 0.053).
The difference between these groups regarding SBP z-score during the day almost reached statistical significance ( p = 0.053).
The patients with ischemic-type biliary lesions showed a trend towards a possible causal relationship with CMV infection (78% vs. 44%, p = 0.053).
When corrected for LA dilatation ( Supplementary Materials Table S1 ), BMI was a borderline significant predictor of AF inducibility (OR 1.14, p = 0.053).
Night-time declamping was associated with worse 1-year post-transplant patient and graft survival before (HR = 1.44(0.99–2.1); p = 0.058) and borderline significant after adjustment for other predictors (HR= 1.49 (0.99–2.22); p = 0.053), findings which were consistent with the analysis of the entire cohort. 4.
Multivariable Cox Proportional Hazards Regression In multivariable Cox proportional hazards regression analysis adjusting for age, sex, and level of obstruction, secretory obstruction (vs structural obstruction) showed a trend toward lower failure risk in the secretory group compared with the structural group (HR, 0.28; 95% CI, 0.077–1.015; p = 0.053) ( Table 3 ; Supplementary Figure S1 ). 4.
Using a linear mixed model with the change to baseline of Yale Global Tic Severity Scale-Total Tic Score (YGTSS-TTS) as a dependent variable, we found a clear trend towards significance for superiority of iCBIT ( n = 67) over placebo ( n = 70) (−1.28 (−2.58; 0.01); p = 0.053).
Interestingly, univariate analysis disclosed preoperative RDW as strictly related to disease-free survival ( p = 0.04), but it was not confirmed in the exploratory multivariable analysis where it was however associated to p close to significance ( p = 0.053).
Although the reduction in the active tDCS group was not statistically significant within the group ( p = 0.30), the sham group demonstrated a near-significant increase in anxiety levels ( p = 0.053).
For both models, male patients had lower GDS scores than female patients (β = −1.98, p < 0.01—first model; β = −1.93, p = 0.003—second model); there were no significant effects for education levels, and pension had a negative association with GDS scores, which was marginally significant (β = −0.0005, p = 0.053).
Chronic kidney disease showed borderline significance with higher long-term mortality in the elderly ( p = 0.053).
Additionally, distance from the anal verge (AV) exhibited a borderline significant association with recurrence in the combined analysis ( p = 0.053). 4.6.
For ‘target absent’ displays, a marginally significant interaction between set size and group was found ( F (4.67,179.68) = 2.82, p = 0.053, η p 2 = 0.056).
However, only borderline significance was observed with the weighted median method (OR Weighted median = 1.07; 95% CI = 0.99–1.14; p = 0.053) ( Figure 2 and Supplementary Table S5 ).
In a subgroup that underwent open RH ( n = 33), adjuvant RT showed a trend toward improved RFS with borderline statistical significance (adjusted HR, 0.098; 95% CI, 0.009–1.027; p = 0.053).
Regarding the aetiology of HF ( Table 2 ), hypertension was the most frequent cause of HF in both groups, although it predominated, almost significantly, in patients without statins (51.5% vs. 47.7%; p = 0.053).
Factors Affecting the Risk of Malnutrition According to SGA Scale In the group diagnosed with non-squamous cell carcinoma, there was a 6.67-fold lower risk of moderate and severe malnutrition (SGA) approaching significance (OR = 0.15; p = 0.0530).
No significant differences in the firing rate between groups after FDR correction for multiple comparisons were found, although DEX and REMI, and REMI in combination with CLONI showed a trend towards significance ( t (209) = 2.64, p = 0.0531; t (269) = 2.28, p = 0.0695).