Excerpts

The lower dose of LEV showed a trend toward a reduced percentage of animals with seizures compared with that in the TBI-VEH group (50% (5/10) vs. 81% (13/16), p > 0.05).

Endosteal circumference in MPS IIIB mice for males increased by 4.6%, but this did not reach statistical significance and increased by 8.7% in females ( p < 0.05).

Tukey’s test, Dunnett’s test, Bonferroni’s Correction and Student’s t -test were used to calculate statistical significance, and the significance level and extremely significant level were set at p < 0.05 and p < 0.01, respectively.

At 24 h post-irradiation, the USH1 fibroblasts showed systematically more γH2AX foci 24 h post-irradiation (GM03889: 1.2 ± 0.2, GM03854: 1.5 ± 0.4, and GM03891: 0.9 ± 0.1 γH2AX foci per cell) than the radioresistant controls (0 ± 0.5 γH2AX foci per cell); however, these differences were at the limit of significance ( p = 0.05) ( Figure 3 A,B).

There was also a weakly significant interaction of the factors antibody, sex and day (F 2,40 = 4.98, p < 0.05).

Notably, progesterone metabolites PM4S and PM5S showed a trend of change similar to that of total BA (TBA) levels, increasing ( p < 0.05) from G60 to G90 then decreasing ( p < 0.05) from G90 to L0 ( Figure 2 a).

Our first titration protocol revealed a significant effect of time ( p < 0.0001) and an interaction between the treatment group and time, which approached significance ( p = 0.05) for maximal coupled respiration supported by glutamate, malate, succinate, and ADP (GMS P ).

On the other hand, when we used the ACh stimulation protocol ( Figure 2 e–h), the average distance between DBH centroids and the nearest α3β4 nAChR centroids (184.0 ± 50.2 nm) was not only significantly lower than the average one when compared with a random simulation for α3β4 nAChR structures (605.7 ± 9.7 nm; p -value < 0.0001, Figure 2 i), but also showed a moderately significant average distance reduction to that obtained for the K + stimulated assays ( p -value < 0.05).

POD activity and MDA content were significantly lower in the shade conditions but an increasing trend with increasing shade was observed ( p < 0.05) ( Figure 2 B,D). 2.1.3.

The differences were judged to be significant and highly significant at * p < 0.05 and ** p < 0.01, respectively. 4.

When the patients’ genotypes are considered, both polymorphisms in the homozygous state displayed a trend towards significance but did not reach statistical significance ( p = 0.05, Table 3 ).

Thus, according to the Tukey multiple comparison test, significant differences regarding the decrease in EA.hy296 endothelial cell viability were reported between the minimum and maximum concentrations studied, after 24 h of treatment, in the case of all liposomes tested ( Figure 16 ), except the CLDM2CP-1 variant, where insignificant or weakly significant decreases in cell viability were recorded (* p ≤ 0.05 and ** p ≤ 0.01).

An almost significant increase ( p = 0.05) was found in the activation of p38, downstream of Y1214 signaling.

The opposite was also observed in tolerance with an evident trend towards lower K/T ratios and higher STF levels in the tolerant recipients ( p < 0.05 by t -test).

For the rs1800629 TNF-α polymorphism, the GA + AA genotypes showed a significant association ( p = 0.038) with the presence of unfavorable histology and were at the limit of significance ( p = 0.05) with high-risk category and INSS stage 4; however, there were no associations with other prognostic factors ( Table A1 ).

The grand average of hydropathicity (GRAVY) scores and gene lengths were found to have highly significant negative correlations with the SCUO values ( p < 0.05), highlighting their substantial impact on the CUB of cp CDSs.

When treated with increasing concentrations of Ang II, miR-34a levels showed a decreasing trend at 24 h treatment but at 48 h and 2 μM concentration its levels augmented (1.63-fold increase, p < 0.05) ( Figure 4 C).

The resulting p -values were considered nominally significant at p < 0.05.

Total serum cholesterol did not show a remarkable influence on HDL lipid composition, apart from a marginally significant positive correlation with the rest GPLs and the ratio of PC/SM (r = 0.23, p < 0.05 and r = 0.22, p < 0.05, respectively) and a negative correlation with plasmalogens PLs (r = −0.21, p < 0.05).

Any difference was considered significant and highly significant at p ≤ 0.05 and p ≤ 0.01, respectively.

With an increase in shading rate, the contents of Chl a, Chl b, and Chl a + b in the leaves significantly increased ( p < 0.05), and the Chl a/b ratio showed a trend in which it increased and then decreased compared to the control ( p < 0.05).

Nominally significant associations ( p < 0.05) were observed between higher maternal levels of IL-8 during early pregnancy with lower gross motor (β: −0.902, 95%CI: −1.697, −0.107, p = 0.026) and fine motor (β: −0.880, 95%CI: −1.500, −0.259, p = 0.006) skills score at age one.

The ratio of NP-positive HSCs of hydrophilic-NP-PBS treated liver was significantly higher compared with that of hydrophobic-NP-PBS treated liver and, also, almost significantly ( p = 0.05) higher compared with that of hydrophobic-NP-olive oil treated liver ( Figure 5 C).

p -values were considered as being significant (*), very significant (**), or extremely significant (***/****) when <0.05, <0.01, or <0.001/0.0001, respectively. p -values > 0.05 were considered not significant (ns).

CD34 loses its significance as a predictor of survival when adjusted for Ezrin positivity in the multiple regression cox model, but remains close to significance ( p = 0.05).