“an evident trend”

Moreover, there was an evident trend to favour ICIs than control therapies for cancer patients in control group with placebo (OS: HR: 0.64, 95% CI: 0.53–0.77, P ≤ 0 . 001 ; PFS: HR: 0.55, 95% CI: 0.47–0.65; P ≤ 0 . 001 ) and chemotherapy (OS: HR: 0.74, 95% CI: 0.68–0.80, P ≤ 0 . 001 ; PFS: HR: 0.79, 95% CI: 0.69–0.90; P ≤ 0 . 001 ), but not with biologics (OS: HR: 0.93, 95% CI: 0.74–1.16, P = 0 . 496 PFS: HR: 0.97, 95% CI: 0.80–1.17; P = 0 . 730 ).

Further, although the differences in water content in raw mutton among the studied categories were not statistically significant, there was an evident trend of decreasing water content with increasing fat content in meat, since the Pearson correlation ( Table 2 ) between water and fat was negative ( n = −0.63; p < 0.01), which is consistent with the research of Hoffman et al.

The opposite was also observed in tolerance with an evident trend towards lower K/T ratios and higher STF levels in the tolerant recipients ( p < 0.05 by t -test).

Moreover, there was an evident trend that naïve CD4 T cells ( P = 0.051) and follicular helper T cells ( P = 0.050) were more abundant in NTRK3 MT NSCLC, while the infiltration of Tregs ( P = 0.009) was more enriched in NTRK3 WT NSCLC (Fig. 5 D).

Moreover, high levels of WNT6 protein expression, evaluated by IHC in a GBM Brazilian cohort (n = 87), also showed an evident trend for shorter OS ( p = 0.069; Figure S7 ), highlighting that both mRNA and protein levels of WNT6 may be used as a clinically valuable biomarker.

24 In line with the findings in pilocarpine models, a one‐hour episode of SE by kainic acid showed an evident trend of increase in hippocampal COX‐2 mRNA levels at 3 days after SE ( P = .071, Figure 4A ) and was able to double the BDNF mRNA expression in the hippocampus ( P < .05, Figure 4B ).

Results showed that YC supplementation significantly increased the hatching rate, showing an evident trend, thus augmenting the rate of fertilization ( P = 0.075) and number of healthy chicks ( P = 0.064).

There is also no statistically significant Time * Group interaction, although there was an evident trend toward the development of such a group effect in both the amount of time spent, and the distance traveled, within the central square ( F (9.108) = 1.79, p = 0.08).

This effect did not reach statistical significance between groups but there was an evident trend in the data towards a greater number of subjects losing pain in the UC-II cohort (p = 0.126).

Our data demonstrated that there was an evident trend that the average driver gene mutations of smokers per patient was higher than that of non-smokers (12 (7–17) vs 7 (1–14) mutations/Mb, p = 0.24), especially in MIBC subgroup (16 (11.5-21.3) vs 7.5 (1–14) mutations/Mb, p = 0.25) ( Supplementary Figure S1A,B ).

These various opinions on the question should speak for themselves, but with most papers showing final height z-scores higher than pre-“adenoids take” ones and the majority tending to be primary-growth patterns, lateral drift toward normative growth is an evident trend that is consistent with our findings [ 55 , 56 ].

Although statistical analysis did not reveal significant differences in symptom scores between Grade 1 and Grade 2 or between Grade 1 and Grade 3, there was an evident trend toward higher symptom scores in Grade 4 compared to Grade 1, with statistical significance observed for chest tightness.

Even though statistic differences were significant in only 1 interval (0.3–0.5), an evident trend still could be illustrated by Fig. 2 .

By plotting the retained introns along their host transcripts, we observed an evident trend that CIRs peaked at the 5′ portion of the transcripts, whereas LIRs peaked at the 3′ portion of the transcripts in five data sets from four cell lines ( Fig. 4 H; Supplemental Fig.

An evident trend could be observed between the concentration of alcohol consumed and decreased rate of gastric emptying (fig 2 ).

Abstract The prevalence of myopia among adolescents in China has continued to rise in recent years, with an evident trend toward earlier onset and higher degrees of refractive error.

The trend equation revealed that with increasing BMD, the BMD difference measured by the two methods indicated an evident trend from positive to negative.

However, considering all the HRD panels, there is an evident trend of higher PFS in crescent order: HRD-negative, HRD-positive, and BRCA1/2 -mutant subgroups [ 52 ]. 4.

Within the three Frailty-CHS groups, the differences in allelic proportions were neither significant nor was there an evident trend ( Fig. 3A ).

In our data, there is an evident trend of this kind, which makes it reasonable to use the DMC.

The gene expression results did not show significant differences between poles, but an evident trend was noticed when medians and means were compared (Figure 1d ).

Among individuals with short sleep duration and snoring, there was an evident trend towards increased AF risk (not statistically significant).

The physicochemical identification of the PS2-derived peptides ( Table 1 ) shows an evident trend in sequence modification and its projected structural behaviour.

Paddy soil exhibits a high level of organic carbon content, an evident trend of carbon sequestration, and a great potential for carbon fixation, which is an important part of the construction of soil carbon sequestration capacity to reduce greenhouse gas emission.

An evident trend of increasing authorship was observed over the past decade: the average in 2020 was 4.8 authors per article, compared to an average of 3.7 authors per article 10 years prior [ 15 ].