Excerpts

Nur77-KO mice showed a trend towards enhanced cardiac function (p = 0.10 ejection fraction, p = 0.08 fractional shortening) assessed by echocardiography ( Supplementary Fig.

As with unilateral AION, the rod-weighted logI 50 for both affected eyes was higher compared to control eyes but the difference did not quite reach significance (median logI 50 for better eyes = −2.40 log cd/m2, for worse eyes = −2.31 log cd/m2 compared to −2.60 log cd/m2 for control eyes, p = 0.10).

TNF-α levels were significantly lower ( p ≤ 0.05), while IL-10 and IFN-γ showed a trend toward reduction ( p < 0.10) in the canola oil group.

At L1, arterioles dilated by 25.4 ± 9.1% (p = 0.10, approaching significance) and venules dilated by 45.6 ± 8.2% (p = 0.023).

When focusing on BAT-candidates, we found that 18 candidates were in the top of expression of the studies considered, being this number only marginally significant (p = 1.01 × 10 –01 ; 95 CI 9.95 × 10 –02 –1.03 × 10 –01 ).

Neutrophilia showed a trend toward decreased mortality risk (aHR, 0.44; 95% CI, 0.17–1.18; p = 0.103) in this model.

However, a trend toward improvement over time was noted in proprioception measured during flexion, with a near-significant main effect of time (F(1,46.0) = 2.767, p = 0.103).

Moreover, we found an interaction between the image set and time point, F (1, 38) = 4.93, p = 0.032, η p 2 = 0.12, a marginally significant interaction between image set and washing condition, F (1, 38) = 2.78, p = 0.104, η p 2 = 0.07, as well as a three-way interaction, F (1, 38) = 4.21, p = 0.047, η p 2 = 0.10.

A similar, but only marginally significant association (ρ coeff. = −0.024, p = 0.105) was found with distance to nearest pulp mill.

Conversely, congenital heart disease, encompassing both cyanotic conditions like tetralogy of Fallot and non-cyanotic conditions such as atrial septal defect, small ventricular septal defect, and patent ductus arteriosus showed an increasing trend from 7.5 to 14.7% ( p = 0.105), though this was not statistically significant.

Conversely, trials originating from non-European/American regions (primarily Asia) showed a negative trend towards publication (OR = 0.16, 95% CI: 0.01–1.11, P = 0.106).

N400 Despite the appearance of an N400 effect for Plausibility in the ERP waveforms, our initial model results indicated this effect was only marginally significant (β = − 0.51 μV, SE = 0.32, Z = − 1.61, p = 0.106).

Notably, laser power approached significance ( p = 0.1076), indicating a moderate influence on width expansion, while its quadratic term ( p = 0.0782) suggests that higher laser power levels contribute to width expansion but with diminishing returns.

There is a clear trend suggesting that diabetes exacerbates cognitive dysfunction in schizophrenia (global cognition: SMD=−0.26; P = 0.1087; 95% CI, −0.59 to 0.08), particularly in domains such as reasoning (SMD=−0.40; P = 0.0109, 95% CI −0.58 to -0.22) and processing speed (SMD=−0.43; P = 0.0005, 95% CI −0.52 to −0.35).

The OR values for AP severity showed an increasing trend (1.44 [CI: 0.92–2.25; p = 0.109]; 2.01 [CI: 1.29–3.14; p = 0.002]; 3.08 [CI: 1.77–5.34; p = 0.000]) in groups with HTG (1.7–5.6, >5.6 and >11.3 mM, respectively), compared to the reference group with seTG <1.7 mM (Figs 3 and 4 , Table 2 ).

Age showed a statistical trend towards significance ( p = .109), suggesting a potential negative association with risky drinking (OR = 0.986, 95% CI: 0.968–1.003).

Other variables did not demonstrate significance, although test algorithm showed borderline significance ( P = 0.11), exhibiting a trend toward better PSD scores in the game-based group.

Out of 5 targets tested ( Klf4, Enos , Ctnnb1 , Bcl2l1 and Sma) , only the expression of Klf4 was significantly upregulated (p = 0.05), while the changes in Sma showed a trend (p = 0.11) without reaching a statistical significance (see Supplementary Fig.

As compared with the control, the mRNA expression of α7 nAChR in nicotine group had an increasing trend ( P = 0.11, Fig. 6A ).

Candidate factors associated with poor overall survival were distant tumours (HR = 2.85, 95% CI 1.77–4.59, p < 0.001), while improved overall survival was near-significant for patients with non-measurable contrast-enhancing residual tumour (HR = 0.68 [0.43–1.09], p = 0.11).

A nonsignificant trend emerged for theta power increase at the F3 and Fz electrodes ( P = 0.11, 0.13, respectively).

Amplitudes in the frontal region were more negative for the American accent as compared to the Indian accent for all parameter sets, with this difference significant at p < 0.05 for the RR15, RR16, and G17 parameter sets and trending toward significance for the H12 parameter set ( p < 0.11).

The enhanced helmet design decreased the volume undergoing large strains by 5% and 29% in the 7.5 m/s frontal and side impacts respectively but this reduction was not significant for the front impact (p = 0.29) and of borderline significance for the side impact (p = 0.11).

Furthermore, when controlling for metastasis at the time of diagnosis, clustering using the 22-miRNA profile (reduced to 18 miRNAs due to mapping attrition) showed a trend toward significance (median RFS 8 vs 27 months, and 64 vs 105 months for metastatic and non-metastatic subgroups, respectively, stratified log rank p = 0.11).

While SUV39H1 also showed a trend toward reduced survival in the high-expression cohort (HR = 2.36; p = 0.11), this did not reach statistical significance (Fig. 3 f), possibly due to the smaller cohort size or differential functional contribution between the two paralogs.