However, if 50 replicates were meta-analyzed, PRKCA became significant in the Asian sample ( N = 16,050, p = 3.4 × 10 −11 ) and in the Yoruba sample ( N = 5,600, p = 5.6 × 10 −9 ) and was trending toward significance in the Luhya sample ( N = 5,400, p = 4.3 × 10 −5 ).
For the preferred hand, significant differences were found in the SFI for grip but trending toward significance for pinch ( P = .0001 for grip; P = .007 for pinch) ( Fig. 2A and B ).
The health subscale was trending toward significance for patients with PHQ-9 > 10; these patients had higher transition readiness than those with lower depression screening scores (68.3 % v. 61.7 %; p = 0.002).
Mean firing rates were significantly different in organoids based on age, with drug condition also trending toward significance (F (6,12) = 9.97; p = 0.0028 and p = 0.08 respectively).
Conversion of pre-NAC biomarker profiles of HR+HER2– and HR+HER2+ to triple-negative breast cancer (TNBC) post-NAC may be associated with worse event-free survival, hazard ratios of 2.23 (95 % confidence interval [CI], 0.90–5.53; p = 0.08), trending toward significance, and 36.7 (95 % CI, 2.2–610.8; p = 0.01), respectively.
Little or no signal was observed in putamen, whereas in the nbM, levels of pS65‐Ub but not CK1δ were increased in esAD ( P < .0001) and lsAD (trending toward significance, P = .011).
Similarly, the ASD group's performance with subject-what questions varied across visits, reaching significance at visit 3 but then trending toward significance only at visit 5 [visit 3: t (13) = 2.30, p = 0.019; visit 4: t (13) = 0.807, p = 0.217; visit 5: t (11) = 1.58, p = 0.07; visit 6: t (10) = 0.857, p = 0.206; see Figure 2B ].
In the RPZ, the MF:SF was 80.0% larger in anxiety subjects than in controls, trending toward significance (4.9, SEM + 1.1 vs. 2.7, SEM + 0.33, respectively; p = 0.031).
group significantly improved in patients with Sjögren’s DED (global, P = 0.011; severity, P = 0.002) and improved trending toward significance in patients with non-Sjögren’s DED (global, P = 0.038; severity, P = 0.081).
Upon final analysis, there was significant benefit for SG in patients with the two highest quartiles of TROP2 expression (220–275 and 275–300), The interaction between treatment and continuous TROP2 expression for OS was marginally significant (range, P = 0.04–0.05), and the interaction between treatment and TROP2 H -score expression by quartiles for OS was trending toward significance ( P = 0.054).
Interaction between treatment and continuous Trop-2 expression for OS was marginally significant (range, P = .04 to 0.05); interaction between treatment and Trop-2 H-score quartiles for OS was trending toward significance ( P = .054; Data Supplement, Table S5).
A negative correlation trending toward significance was observed between the percent tumor volume of the HV-HC habitat and the percent tissue area of necrosis identified from H&E-stained slides ( r 2 = −0.47, p = 0.05, Figure S6B ).
Adenosquamous carcinoma was statistically significantly different from poorly differentiated cases ( p = 0.04) and trending toward significance from moderately differentiated cases ( p = 0.05).
The absolute volume of whole body LM was 15% lower in FSHD, compared with controls, trending toward significance ( p = 0.05).
Without acute attack with 2 significant subscales (PF and BP, P = 0.04) and 1 subscale trending toward significance than with acute attack group (GH with P = 0.05) and a lower PCS composite score ( P = 0.001), one variable was associated with better QOL in the RP, working status (score of 35.42 for stay at home versus 88.33 for working; P = 0.02), as shown in Tables 3 and 4 .
Compared with placebo (rather than baseline) depression, perceived stress and general anxiety were significantly improved with oxaloacetate/vitamin C treatment, with aggression trending toward significance ( P <0.05, P <0.05, P <0.05 and P =0.060, respectively).
Metabolites and proteins were considered significantly different at p -value ≤ 0.05 and trending toward significance at p -value > 0.05 and < 0.1 (based on Tukey’s HSD test).
A difference was considered significant for P values ≤ 0.05 and trending toward significance for P values >0.05 to ≤0.10.
Additionally, the relationship between NE and left amygdala activation during the neutral face condition was trending toward significance, with t (56) = 2.15 and P = 0.05.
The relationship between proportion of time (instead of dwell time) was in the same direction and trending toward significance ( r (24) = 0.39, p = 0.05).
Within−time correlations revealed that dietary restraint was positively associated with concurrent weight at grade 4 and was trending toward significance at grade 3 (grade 3: B = 0.03, p = 0.05 grade 4: B = 0.03, p = 0.002).
When absolute VO 2 Peak (mL·min −1 ) was defined as the endpoint, only handgrip strength was significantly correlated ( P = 0.02) while 30sec-STS was trending toward significance ( P = 0.05).
A p -value Bonferroni-corrected for 378 independent liver enzyme loci was used to determine significance ( p < 1.3 × 10 −4 ); alleles trending toward significance ( p < 0.05) were also reported separately.
In an adjusted model that included both sleep onset SD and caloric midpoint SD, associations between both metrics with CIMT were attenuated, with sleep onset SD trending toward significance ( B =0.044±0.016; P =0.05), whereas caloric midpoint SD was not significant ( B =0.018±0.016; P =0.26) (Table 5 ).
20 Though our study did not find a statistically significant increase in the Knowledge and Screening content domain between the pre- and post-test, the result was very close to being statistically significant ( p = 0.0506), which indicates the result was trending toward significance.