Excerpts

Although the expression of PSMA3-AS1 in relation to the size of the tumor was not statistically significant, a positive trend towards higher PSMA3-AS1 expression in bigger tumors was demonstrated ( p = 0.06), ( Figure 6 ).

The Dunn–Bonferroni post hoc test indicated that the most notable difference in thyroid volume was observed between the CT and TT genotypes, although it was still just a trend toward significance ( p = 0.06). 3.

There was a borderline significant increase in G3/4 diarrhoea (OR: 1.75, p = 0.06), but no effect on treatment discontinuation without progression (OR: 0.87, p = 0.25).

Alterations in ATM were more frequent among H/L patients (17.3%) compared with NHW patients (7.9%), a difference approaching borderline significance ( p = 0.06).

We recorded a significant increase in striatal ChAT + interneurons in IR-HG sham mice versus healthy CTRL and a strong trend in the same direction between IR-NG and CTRL mice ( p = 0.06) ( Figure 5 a,c).

Moreover, the median mtDNA copy number was more than doubled for myopathy-derived fibroblasts, though this only reached borderline significance when compared to healthy-tissue-derived fibroblasts ( p = 0.060; Figure 6 G).

A marginally significant association was found between the presence of the SDF-1 (c801A) allele and the development of PDR ( n = 89 eyes, p = 0.06).

The mean CLH2 expression differed significantly, and 45M1 had a strong trend toward significance ( p = 0.06) among the three groups ( Figure 1 B).

Similarly, ex vivo samples from IRL201805Res patients revealed a strong trend ( p < 0.06) at 72 h for greater intracellular expression of IDO when compared with Pbo at the same time-point.

pure 50 mGy β-irradiation—24 h) were close to significance (two-sample independent t -test with Welch correction, p = 0.06).

Dunnett’s post hoc testing after ANOVA revealed a significant preventive effect for ectoine and a clear trend for NADA ( p = 0.06). 5-Hydroxyectoine had considerably smaller effects that did not prove to be statistically significant, probably due to the sample size of n = 10. 3.

Hepatic HIF-1α mRNA expression increased in both CLD models, reaching significance in the toxic model, whereas it was borderline significant ( p = 0.06) in the BDL model.

A decreasing trend was observed in plateletcrit (PCT; p = 0.0600) and eosinophil percentage (EOS, p = 0.0880), whereas the LUC ( p = 0.0656) showed an increasing trend ( Table 3 ).

Tissue MCP-1 also demonstrated a trend toward significance by health status ( p = 0.06), where unhealthy animals had higher levels ( Supplementary Table S5 ).

The first principal component (captured by changes in the intake of kilocalories, carbohydrates, disaccharides, sucrose, and added sugar) showed a borderline significant association with changes in leptin levels ( p = 0.060).

Interestingly, in LNCaP cells, we observed an almost significant increase in ROS content ( p = 0.06) after ALA compared to the control, concomitantly with a significant upregulation of the antioxidant enzyme SOD1 after 48 h.

Nine VOCs increased towards death and a further two approached significance ( p < 0.06, BH adjusted).

It is also noteworthy that the interaction between DHT treatment and litter size reduction is on the brink of significance for pAMPK-Thr172/AMPK ratio (F (1, 20) = 3.87, p = 0.06).

Notably, for the aif1 gene, the treated AD mice showed a trend toward less gliosis compared to non-treated mice ( p = 0.06). 3.

In our experience, despite a statistical trend ( p = 0.06) in inducing IL6 protein expression in HTR-8/SVneo cells, a low-dose tacrolimus of 10 ng/mL was not sufficient to significantly induce the expression of this pleotropic cytokine in these EVT cells when cultured under nitrosative stresses in vitro ( Supplementary Figure S2 ).

In our EpiPath cohort, there was a strong ELA-associated increase in immunosenescence-associated chronic inflammation, together with increased T h 17 cell numbers, although this narrowly missed significance ( p = 0.06, [ 51 ]).

Two-way ANOVA with virus treatment and time after HFS as independent variables and fEPSP slope as dependent variable detected a significant treatment x time interaction (F(158, 632) = 2.4, p < 0.0001), a main effect of time (F(79,632) = 4.2, p < 0.0001), and a strong trend towards main effect of treatment (F(2,8) = 3.9, p = 0.06; Figure 5 h).

Although higher redox ratio tends to correspond to higher ROS, the correlation has a borderline significance ( p = 0.060). 3.

Moreover, flow cytometry analyses showed a strong trend of higher percentages of ABCG2-positive RBCs in MPN patients prior to any treatment compared to healthy individuals ( Figure 1 D, p = 0.06) further validating our mass spectrometry data from untreated patients [ 11 ].

We also reanalyzed our microarray data searching for genes of the Ub/Ub-like pathways close to significance in a context of oxidative stress (0.05 ≤ p < 0.06).