It should be noted, however, that these correlations narrowly missed significance when corrected for multiple comparisons at the most conservative Bonferroni threshold ( P = 0.016).
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“narrowly missed significance”
Sighted at
p=0.051
In the literature
Moderate deficiency (10–20) showed a strong trend toward worse OS that narrowly missed significance. Liver metastasis was independently associated with significantly worse OS (adjusted HR 1.42, 95% CI 1.06–1.91, p = 0.02), consistent with published literature where HRs for liver metastasis typically range from 1.4 to 2.0.
mAb 12A1 prolonged survival ( P = 0.053), but the increase narrowly missed significance at the P = 0.05 level.
43 , 44 Interestingly, CARD16 expression was lower in CIA than in other forms of arthritis and only narrowly missed significance (p = 0.0506), while CARD18 expression trended higher but was not significant ( Figure 1A ).
In multivariate analyses with CCI and sex, ECMO/ECLS narrowly missed significance (p = 0.0507).
This effect was not found to be significant in the main analysis, although it only narrowly missed significance, with p = 0.051.
Neurodisability scale scores differed significantly across treatment response groups following prednisolone therapy ( P = .01), and post-hoc comparisons suggested a trend toward lower scores in complete responders compared to partial and nonresponders, although these differences narrowly missed significance after Bonferroni correction ( P = .051 and P = .053).
A small ( N = 31) prospective, single-arm, 24-month study using ranibizumab for the treatment of retinal angiomatous proliferation (RAP) also identified a negative correlation between age at baseline and final best-corrected VA (BCVA; R = −0.357, p = 0.049, Spearman's rho test), although when analyzed using multiple linear regression analysis it narrowly missed significance ( p = 0.051) [ 19 ].
The variation was greater for NpP than NcP‐AEP (main effect group: F [3, 10.5] = 15.3, p = .001, η 2 = .383, post hoc p = .002) and MP ( p = .004) groups, and narrowly missed significance compared with the NcP‐FP group ( p = .051).
Although the OS difference in the overall OPTiM population narrowly missed significance ( p = 0.051) file-(Ref) [ 43 ], a pre-specified subgroup analysis of patients with earlier-stage metastatic disease showed a marked survival benefit: in stage IIIB–IVM1a melanoma, median OS was 41.1 months with intralesional T-VEC vs. 21.5 months with GM-CSF (HR 0.57, p < 0.001) [ 75 ].
In the adjusted analysis, PD-L1 expression was associated with smoking quitters (OR = 3.35; P = .029) and narrowly missed significance for smokers (OR = 2.95; P = .051).
RANTES levels were significantly higher in people with acute kidney disease [117.78 (36.42-166.66) p=0.0435] and narrowly missed significance in patients with hypertension [96.41 (46.17-163.92), p=0.0511].
Epregistry and PIRCHE-T2 showed significantly higher mismatch scores in the dnDSA + group compared to dnDSA - ( Figures 2A, B ), while PIRCHE-B showed a similar trend that narrowly missed significance ( Figure 2C , p = 0.052 ).
In hurling, 66% of incidents were illegal, but this result narrowly missed significance ( p = 0.052).
A similar trend was identified for suggested frequency of DDA use, but this narrowly missed significance ( P = .052).
Second, for the employee perspective, health deterioration moderated the relationship between staff care and disclosure intentions (study 1: B = −0.27, SE = 0.12, t = −2.30, p = 0.023, see Table S1 ), but narrowly missed significance for actual disclosure (study 2: B = 0.18, SE = 0.09, t = 1.95, p = 0.052, see Table S1 and Figure S1 ).
In the regression analyses, the AS values narrowly missed significance for the difference in intercept (with p = 0.052 for ROM, and p = 0.055 for PAV) but showed a significant difference in slope (with p < 0.0001 for both) (Figs. 1 , 2 ).
Nevertheless the comparison between these two groups narrowly missed significance ( p = 0.052).
By contrast, the level of another ER chaperone, calreticulin, 50 was decreased in Rpgrip1 nmf247 retinas, albeit the difference between wild type and Rpgrip1 nmf247 narrowly missed significance ( P =0.053; Figure 2a ).
Also, the DA response to reward was significantly correlated with approaches to the CS+ during presentation across all training sessions, but narrowly missed significance ( p = 0.0540) in acquisition sessions in VAChTcKO mice (Fig. 5f ).
FSL-SIR-FLX narrowly missed significance in a two-way ANOVA compared to FSL-FLX rats ( p = 0.0542).
Narrowly missed significance ( p = 0.055) was also found in the increase of Total PA among these mothers.
The difference between stage I and IVA reached significance in the 7th UICC edition but narrowly missed significance in the 8th UICC edition (p = 0.055).
The group difference between WASH+S+TAU and WASH+TAU narrowly missed significance ( d = −0.40, p = .055; see Table S9 ).
There was also a difference between male and female pain patients that narrowly missed significance (abstract vs. figurative: male 6 vs. 20, female 3 vs. 47; p = 0.055).