However, estimated differences for CPI Group participants’ MoCA-Blind test scores compared to the ADRC cognitively intact controls approached significance at baseline ( p = 0.066) and were significantly worse than the controls’ scores after CPI treatment (6 months for CPI Group participants’ scores compared to controls’ scores at 12 months, p = 0.011).
However, in the group that died of a non-neoplastic cause, there were differences in the mean survival times according to the location in favor of the left location (RCC 32.23 ± 6.69; LCC 69.105 ± 10.44) very close to significance ( p = 0.066).
The presence of the HLA-A03 supertype showed a trend in association with protection against developing irAEs that did not reach statistical significance (RR = 0.35, 95%CI 0.12–0.96, p = 0.066).
However, there was no statistically significant difference in the subgroup analysis of RCTs alone (OR: 0.788, 95% CI: 0.589–1.054, p = 0.108), whereas borderline significance was noted when analyzing balanced studies alone (OR: 0.802, 95% CI: 0.634–1.015, p = 0.066).
Differences between surgeons were borderline non-significant ( p = 0.066) ( Table 2 ).
While no statistically significant association was confirmed, the result approached significance ( p = 0.066).
Their findings indicated that PORT significantly improved OS (HR, 0.74; p = 0.021) and showed a trend toward better LRFS (HR, 0.62; p = 0.066) compared to surgery alone.
71.4% for low LMR), this specific marker showed a trend toward significance but did not reach the standard threshold (log-rank p = 0.066; Figure 2 E). 3.4.
However, the BIR-to-SIR group presented with statistically significantly bigger primary tumors ( p = 0.003) and higher T stages ( p = 0.007) and a nearly significant higher rate of lymph node (LN) involvement ( p = 0.066).
Although the co-deletion of RB1 and BRCA2 was only seen in two cases, it showed a marginal trend toward association among all primary GISTs ( p = 0.066), partly reflective of their chromosomal proximity.
In addition, although the difference was not statistically significant, patients with <3 brain metastases showed a favorable trend toward longer OS compared with those with ≥3 lesions (33.9% vs. 29.7%, p = 0.066).
Despite their considerable melanoma cell expansion, MeWo-RhS only showed a trend towards an increase in M-CSF secretion ( p = 0.0664), compared to the RhS control ( Figure 2 b).
The non-SC subtype was an independent prognostic factor for both worse PFS (adjusted-HR = 1.62; p = 0.016) and OS (adjusted-HR = 1.64; p = 0.015), whereas a Ki-67 index of ≥55% (significantly enriched in the SC subgroup; Table 1 ) was an independent prognostic factor for worse PFS (adjusted-HR = 1.80; p = 0.028) and showed a trend towards worse OS (adjusted-HR = 1.63; p = 0.067).
Moreover, Table S1 indicates an increasing trend of SPON2 expression in poorly differentiated tumor tissues compared to moderately to well differentiated tumor tissues ( p = 0.067).
When Gal-7 expression was high and Gal-8 was low, DDFS was significantly impaired ( p = 0.009, median DDFS in all subgroups NR, Figure 7 b) compared to the rest of the patients, as well as PFS with a borderline significance ( p = 0.067, median PFS in all subgroups NR, Figure 7 c).
In multivariable models including CA 19-9, the FT3/FT4 ratio showed a near-significant exploratory association with resectional status (OR = 1.90, p = 0.067), whereas isolated FT3 lost statistical significance (OR = 1.69, p = 0.341).
This survival difference remained only a trend towards significance on multivariate analysis ( p = 0.067, Supplementary Table S4 ).
Lower values of HRF in the IR and OR in VHL patients with RH were found, compared to the group of VHL without RH, while p -value was at the limit of significance between the two groups concerning the number of HRF in the total retina ( p = 0.0677).
Only a statistical trend was observed for cancer type ( p = 0.068), further supporting the notion that exceptional adaptation is less dependent on medical characteristics of the disease.
30.2%, p = 0.197); however, a statistical trend ( p = 0.068) in favour of adjuvant treatment exists when considering overall disease free survival (16 months (IQR: 10.5–27) vs. 14 months (IQR: 9–22)).
In the FET hotspot analysis, the best similarity (good agreement) with GTV 2 was found in the G1 group using a 90% SUVmax delineation method and showed a trend of statistical difference with those (poor agreement) in the G2 group (OV’ = 0.67 vs. 0.38, respectively, p = 0.068); whereas the best similarity (good agreement) with GTV 3 was found in the G1 group using a 80% SUVmax delineation method and was significantly higher than those (poor agreement) in the G2 group (OV’= 0.72 vs. 0.35, respectively, p = 0.014).
The presence of LVI was also associated with relapse of disease ( p = 0.018), while we noted a statistical trend toward the relationship between LVI+ and death outcome ( p = 0.068).
In addition, a marginal significance was found with patients drinking less than 7 drinks per week, with an OR of 4.1786 (95% CI 0.8995–19.4103, p = 0.0680).
CTP A patients in the nivolumab arm showed a trend to longer mOS, with 31.2 months (95% CI: 12.6–72.8) compared to 14.2 months (95% CI: 1.9–26.5) in the sorafenib only arm (HR 1.80; 95% CI: 0.95–3.44, p = 0.068; Figure 2 A).
high-grade DDIs had better outcomes in terms of OS ( p = 0.0012) and a trend toward significance in PFS ( p = 0.068).