failed to reach significancep < 0.05
Moreover the test for the interaction between the linear trends failed to reach significance [F(1,26) = 3.94, p < 0.05].
Moreover the test for the interaction between the linear trends failed to reach significance [F(1,26) = 3.94, p < 0.05].
Genes were discarded from the analysis if differential expression failed to reach significance (adjusted p < 0.05 with Benjamini–Hochberg correction).
The loss of renal transcriptional identity followed a similar pattern to the chromatin accessibility changes: PAX8 KD alone showed a negative enrichment for the proximal epithelial signature C4 but failed to reach significance (p < 0.05) and P8 1 S1 1/2 (A) showed significant downregulation of the signature which reduced further over time (P8 1 S1 1/2 (LT)) ( Figures 4 B and 4C).
For the secondary outcome quality of life, the between-group effect reached a small to medium effect size but failed to reach significance ( F 1,90 = 3.92; η p 2 = 0.042) ( P = .05).
In the CORT-treated group, there was an apparent reduction in premature responses in weeks 1 and 3 but this failed to reach significance at p < 0.05 (GROUP: F 1,14 = 3.765, p = 0.073; post hoc: ps ≤ 0.060; Fig. 2 D, n = 8/group).
Statistical analysis, however, failed to reach significance, but showed a positive trend (mean GGT seroconversion 173.20 IU/mL vs. no seroconversion 44.89 IU/mL, p = 0.052).
From BL to TW3, we noted an increasing trend in TIGIT + CD56 dim NK cells that failed to reach significance ( p =0.0537) and a significant increase of said cells at TW48 (Figure 3 C, left panel).
Trial times A main effect of model approaching significance [ F (3,33) = 2.783, p = 0.056, ES = 0.202] suggested that trial time was affected by the model being constructed, follow-up comparisons however, failed to reach significance ( p > 0.017).
All other main and interaction effects failed to reach significance, but the three-way interaction between DPI , WM-position and Dot-location nearly reached significance [Wilks’ lambda = .41, F(6,12) = 2.85, p = .058, η p 2 = .59], suggesting modulation in the interactions between WM-position and Dot-location based on the time of presentation of the Dot (DPI).
Using the Spt ROIs to examine activation as a function of lag (see Figure 5 , bottom left) during recognition memory reveals a marginally significant lag effect for the AR condition [ F (2,54) = 2.97, p = 0.059; ANOVA with lag parameterized with linear and quadratic trends] but not for the VR condition ( p > 0.08); while the lag by modality interaction failed to reach significance [ F (2,54) = 2.17, p = 0.12].
Post hoc paired-sample t -tests reported significant difference between Static and Moving conditions at the presentation duration of 1200 ms [ t (11) = −4.586, p = 0.002], though it failed to reach significance under 800 ms [ t (11) = 0.561, p > 0.999], and with marginally significant difference under 1000 ms [ t (11) = −2.717, p = 0.060] presentation duration (all Bonferroni-corrected).
The main effect of the end approached significance, F (1, 143) = 3.44, p = 0.066, partial ω 2 = 0.016, whereas the main effect of the beginning marginally failed to reach significance, F (1, 143) = 2.12, p = 0.120, partial ω 2 = 0.007.
The mRNA expression of the pro-neuronal factor FGF-2 showed a trend toward an increase (Figure 4B ), yet this failed to reach significance (ANOVA p = 0.068, n = 6 each).
Sleep disturbance (defined by a Richards Campbell Sleep Score of >33) was significantly associated with anxiety ( P = 0.009), but not with depression, despite a statistical trend that failed to reach significance ( P = 0.07).
However, the interaction failed to reach significance at the short interval ( F = 1.350, p = 0.26) and was close to significance at the long interval ( F (1,23) = 3.553, p = 0.072).
Among circulating markers, sodium and creatinine were significant predictors (both p<0.01), uric acid only reached borderline significance (p = 0.0808) and haemoglobin failed to reach significance.
Contrasts between angry and neutral sentences failed to reach significance but showed a trend into the same direction (F(1, 22) = 3.18, p = .09).
Kaplan–Meier survival analysis of AnxA6 with outcome in PDAC Kaplan–Meier survival analysis carried out using GraphPad PRISM revealed a clear trend towards high AnxA6 expression (IHC score 3+/4+) being associated with a poorer outcome in the 57 PDAC cohort ( P =0.2242); however, this failed to reach significance.
The 5-week assessment HRT showed an intermediate value (M = 377.82, SE = 4.68) that failed to reach significance when compared to baseline ( p = 0.73) and barely missed significance compared to the final assessment ( p = 0.52).
LXRα gene expression levels showed a trend towards increase in the SGC707‐treated mice as compared with the other groups; however, this failed to reach significance (Figure 2 A).
A further 4 showed a trend towards downregulation which failed to reach significance, while 4 showed no change in expression despite a finding of significant expression by microarray analysis.
This shows a clear trend; however, the analysis failed to reach significance (FDR 0.397).
High B7-H4 mRNA levels showed a trend towards a good prognostic impact on OS but the difference failed to reach significance (Figure S3a, c–f).
As previously noted, although there was a positive trend in frequency and audiometric ABGs, our results failed to reach significance.
While a statistical trend was noted between assessments of ROC curves for MRPP and APMHR, overall this failed to reach significance (z = 1.8, p = 0.072; Fig. 2 ).