“did not reach statistical significance”

In contrast, hyaluronidase plasma levels showed a trend toward higher levels in the HES 130/0.4 group at 8 and 24 h after CLP, which did not reach statistical significance (Additional file 1 : Figure S1).

One immunoglobulin dose-comparative study (400 mg/kg daily given for 3 days versus, for 6 days) showed a trend for greater benefit in the prolonged treatment course in terms of median time taken to be able to walk with aid, but this result did not reach statistical significance [ 53 ].

Although there was a slight trend towards higher EDSS values in seropositive patients compared to seronegative patients (5 vs 4), the difference did not reach statistical significance.

Effect of Fenofibrate Administration on Nitrate (NO 3 − ) and Nitrite (NO 2 − ) Concentrations in Lung Tissue in a Su/Hx-Induced PAH Model In lung tissue, a decreasing trend in NO 3 − concentrations was observed in the Su/Hx group compared to the control group; however, the difference did not reach statistical significance.

G6D-NAC (2.0 and 5.0 mg/kg) treatment showed a trend of decreased TSPO mRNA expression, but did not reach statistical significance (Fig. 4 i).

20 52 Nevertheless, while the ultrasound-based model showed a trend for a better association with enthesophytes compared with DEI, this difference did not reach statistical significance.

A marginal trend was observed for FT4, but it did not reach statistical significance after adjustment.

A clear trend toward a reduction of T cells were observed in both the Budesonide and PPS‐treated groups, although the effects did not reach statistical significance compared to sham‐treated OVA‐challenged animals (Fig. 5 B).

With regard to effects on physical activity (PA), although the 9.7% increase in the PAQ score over the course of the program may be interpreted as a positive trend, it did not reach statistical significance.

Although data indicated a clear trend for 1 μM G-1 48 h treatment lowering the proportion of stimulated cells in G2/M phase, this effect did not reach statistical significance compared to controls ( Figure 1B, 1D ).

While STK11 mutation did not reach statistical significance in the complete model ( P = 0.069), it showed a trend towards worse OS, indicating that STK11 mutation may still have a potential role in influencing survival outcomes.

The stimulation group showed a trend of higher collagen fiber content than the sham group in both tissues, but this difference did not reach statistical significance (Fig. 2 B,C).

In lung tissue, ASPD treatment significantly reduced IL-6 levels, whereas TNF-α levels showed a decreasing trend but did not reach statistical significance ( Figure 7 a,b).

IMP4 was significantly upregulated in GSE66407 , whereas it showed a decreasing trend in GSE179285 and GSE11223 , although the differences did not reach statistical significance ( Figure 4C ).

Although plasma GFAP levels showed a trend toward improved classification of disease severity, the difference compared with plasma NfL levels did not reach statistical significance (p = 0.55).

LLND showed a trend toward increased risk but did not reach statistical significance after adjustment (OR 4.90; 95% CI 1.03–23.16; p = 0.07) (Table 3 ).

Surgical intervention Although the difference in operative rates between groups did not reach statistical significance, a notable trend was observed.

During the three months follow-up, there was a notable trend of lower mortality in patients who received a cementless THA (8.8%) compared to the cemented group (16.5%), but it did not reach statistical significance ( p = 0.06).

Although a positive trend was observed, the reduction in overall mortality did not reach statistical significance.

Moreover, these interventions showed a trend toward reduced metastases to the pelvic adipose and mesentery, though the differences did not reach statistical significance (Fig. 1 N and S5B).

Alcaligenes showed a positive trend with neophytadiene (r = 0.734), though this association did not reach statistical significance after correction and should be interpreted with caution.

Notably, there was an increasing trend in the proliferative index of PDGFRα − Olig2 + cells (% PDGFRα − Olig2 + Ki67 + /PDGFRα − Olig2 + cells), although it did not reach statistical significance (p = 0.2) ( Figure 2L ).

Additionally, the Rs-2018 regimen showed a trend towards improved survival in both EFS and OS compared with the Rs-99 regimen, particularly in the high-risk subgroup, although it did not reach statistical significance.

Communication scores approached significance but did not reach statistical significance ( P = .061).

Systolic and diastolic blood pressure showed a trend of increase at 2-, 3-, and 4-week intervals in the ibrutinib group rats compared to the control group rats, although the observed changes did not reach statistical significance ( Figure 2 D).