The DSS and OS of patients with stage II disease also showed a trend towards improvement, but the differences versus Group S did not reach statistical significance.
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Of five cell lines tested (IGROV1 cells did not form spheroids at all), we observed significantly increased numbers of spheroids in the SP fraction of four models (i.e., A2780, A2780V, B16/92, B17/92), whereas in the fifth cell line (i.e., B2/92) we could only detect a slight trend that did not reach statistical significance (Fig. 3C + 3D).
In the other parameters, there was a positive trend toward a protective effect of treatment for BV against preterm delivery, which did not reach statistical significance ( Table 3 ).
Moreover, these interventions showed a trend toward reduced metastases to the pelvic adipose and mesentery, though the differences did not reach statistical significance (Fig. 1 N and S5B).
In patients with mild NPDR, there was a slight trend towards visual improvement, though it did not reach statistical significance.
Current smoker versus nonsmoker at time of diagnosis showed a trend towards greater reduction in BMI; however, it did not reach statistical significance.
A possible trend toward a worse prognosis was observed in patients with metastatic pancreatic NETs and metastatic pheochromocytomas or sympathetic paragangliomas but did not reach statistical significance.
Although the analysis did not reach statistical significance, the enrichment score showed a decreasing trend upon XAV939 treatment, consistent with its known inhibitory effect on the Wnt/β-catenin pathway.
Higher prevalence of OX40+ Teff cells also showed a trend of improved overall survival, but did not reach statistical significance.
Conversely, low expression of TrkB and TrkC showed a trend toward better prognosis, although these associations did not reach statistical significance ( p = 0.150 and p = 0.300, respectively).
Although the differences did not reach statistical significance, there was a clear trend toward lower T cell proliferation rate when stimulated with DCs activated in the presence of IMOD.
Surgeon 4 showed a trend toward decreased operative times, but this did not reach statistical significance ( P < .0542).
The pooled analysis showed a trend toward higher conversion rates with single-port laparoscopy, but this did not reach statistical significance (odds ratio: 1.32; 95% CI: 0.99–1.77; p = 0.06; I 2 = 38%) ( Figure 3 A–E). 3.4.2.
This change, with 11 answers changing from correct to incorrect and 3 from incorrect to correct, resulted in a p -value of 0.057, which suggests a slight trend toward a change, but it did not reach statistical significance. 4.
However, this association did not reach statistical significance in the left eye ( p = 0.058), although it showed a trend toward significance.
A clear trend for lower OR was documented in patients with mild NPDR compared to patients with moderate and severe NPDR, although the difference did not reach statistical significance.
In the present study, inclusion of a single lap belt PT in addition to the shoulder belt PT showed a trend of reducing submarining risk for the reclined FE-HBMs, although this effect did not reach statistical significance for the simulation sample (p = 0.22).
The kinetics of inactivation for the E443A and E443A-E445A-E447A mutant channels demonstrated a strong trend to decrease the inactivation rate but did not reach statistical significance.
Comparison of mean continuous variables revealed that the levels of TC and TG were significantly higher in the study group than those in the control group, while blood glucose and BMI exhibited an increasing trend, however, the difference did not reach statistical significance (Table 2 ). 3.4.
After 12 h of treatment with 0.2 μM of LLL12, SCCF2 showed a trend towards increased caspase 3/7 activity (data not shown), but this difference did not reach statistical significance until 24 h of treatment.
Having DR4/DR8 or DR4/DR9 genotypes showed a trend toward rapid progression in β-cell dysfunction, but each alone did not reach statistical significance (DR4/DR8, HR 2.56; DR4/DR9, HR = 1.73 in model 1).
Insurance type (public vs private) showed a trend in the expected direction (public insurance patients had higher risk scores on average) but did not reach statistical significance in this sample (p = 0.12).
In contrast, although reductions in pork toughness and firmness were observed in these groups, these differences did not reach statistical significance, indicating only a numerical trend toward improved texture.
MIG level also showed an increasing trend but did not reach statistical significance (486 ± 1401 vs. 649 ± 1147 pg/mL, P = 0.069).
In contrast, sex, hearing loss duration, and the mode of hearing loss onset did not reach statistical significance in relation to either audiometric outcome, although hearing loss duration showed a trend toward significance given the proximity of its p -values to the 0.05 threshold. 3.4.