Although data indicated a clear trend for 1 μM G-1 48 h treatment lowering the proportion of stimulated cells in G2/M phase, this effect did not reach statistical significance compared to controls ( Figure 1B, 1D ).
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Although the differences did not reach statistical significance, there was a clear trend toward reduced TNF-α levels and increased IL-10 levels.
While γ-GTP levels showed a decreasing trend in the treated group, changes in AST and GSH did not reach statistical significance between both groups.
Those in the top quartile of SII_max (extremely high peak inflammation) also showed a trend toward higher mortality, though this difference did not reach statistical significance in our sample.
Our results showed a trend towards higher levels of N-glycosylation and trastuzumab resistance, but this did not reach statistical significance ( P = 0.081) ( Fig. 4c ).
For HDL-C, while the change in prevalence did not reach statistical significance in the medication-free subgroup, the odds ratio analysis showed a trend toward improvement, with the odds of HDL-C increase being 1.81 in females and 2.22 in males, postintervention.
Death group showed a trend toward increased CSF concentrations of endostatin/collagen XVIII after TBI versus survival group, which was especially significant at day 3 ( P = 0.026) and day 5 ( P = 0.001), although this did not reach statistical significance at 24 h and 7 days after trauma ( Table 2 and Figure 2(a) ).
Communication scores approached significance but did not reach statistical significance ( P = .061).
Furthermore, the correlation between the TyG index and αS-SAA parameters—TTT and T50%—did not reach statistical significance but showed a trend-level association(Additional file: Figure S3 ).
Achieving a textbook outcome showed a trend toward improved OS but did not reach statistical significance (HR = 0.770, 95% CI: 0.463–1.281, p = 0.31).
Comparisons between Group 1 and Group 2 ( p = 0.1413) and between Group 2 and Group 3 ( p = 0.0535) did not reach statistical significance, although the latter showed a trend toward significance.
The Shannon index also showed a decreasing trend, although it did not reach statistical significance ( Figure 4 c).
Other aspects measured also showed a trend towards improvement in the PACE group, although this did not reach statistical significance.
At 3 weeks post-irradiation, there was an overall trend towards a lower hemoglobin concentration, lower MCV, lower platelet count, and lower WBC count in the MIWI2 −/− mice ( Figure 4 ), but the differences did not reach statistical significance.
Ail-E43D showed a trend toward reduced binding but did not reach statistical significance (p = 0.08).
Though difference between DML, DMH and DMN groups did not reach statistical significance, nesfatin-1 injected mice showed a trend toward a dose-related decrease in plasma FFA levels (DML 2.57±0.34 mmol/L vs.
a positive trendgold
Association Between Serum Lycopene and Total Sperm Motility For total sperm motility, lycopene supplementation showed a positive trend that approached but did not reach statistical significance (SMD = 0.28, 95% CI [−0.04 to 0.61], p = 0.083).
In both tasks, while the TBI-saline showed a trend of improved recovery over time, their performance did not reach statistical significance (p's>0.05) compared to Day 0 post-TBI.
Although rs62140629, rs4952027, and rs7601904 exhibited a trend toward significance, they did not reach statistical significance.
In our study, however, we found that BRF2 plays critical role in prognosis in 37 patients with AC; however, the log-rank test showed a trend towards better overall survival in the high BRF2 group in 40 patients with SCC but this did not reach statistical significance ( P > 0.05).
Although the expression levels of ERCC1 transcript showed a trend of decreasing from wide type (TT) to the homozygous variant (CC) genotype of rs11615 polymorphism in CHB population, the difference did not reach statistical significance.
Although most of the combination therapy showed a trend toward decreased incidence of severe exacerbations, the difference did not reach statistical significance.
In contrast, while younger individuals, males, and APOE4 carriers showed a trend toward improved AUC and model fit, these changes did not reach statistical significance.
In an exploratory finding, tumors with high Ki-67 (≥30%) or small initial size of tumor (≤2 cm) showed a trend toward a higher pCR rate than those without but they did not reach statistical significance (Table 3 ).
In the 2012 meta-analysis trastuzumab administered for 12 months was associated with an improvement in OS [HR 0.67 (95%CI 0.57–0.80)]; although trastuzumab treatment for ⩽6 months also showed a trend towards an improvement in OS, it did not reach statistical significance [HR 0.55 (95%CI 0.27–1.11)] [160] .