“did not reach statistical significance”

47.0 (43.0–51.0) mm, p = n.s., p < 0.05) showed a trend for an age-dependent increase, however, the differences between age groups did not reach statistical significance.

Furthermore, as shown in Figure 1D , the fecal moisture content of the NM was significantly lower ( p < 0.05), and the fecal moisture content of the HF of mice showed an increasing trend, but this difference did not reach statistical significance. 3.2 Effects of the combination of Polygonatum sibiricum and Poria cocos on colon pathology in mice with spleen deficiency constipation A normal intestine is composed of the mucosal, submucosal, muscular, and serosal layers.

Although a decreasing trend in NK1R ( Tacr1 ) was observed, it did not reach statistical significance.

Although these associations were nominally significant, they did not reach statistical significance after applying the Bonferroni multiple corrections, potentially due to the limited sample size.

Although this result did not reach statistical significance, it showed a clear trend in favor of combination therapy.

Although psychological well-being also demonstrated an increasing trend, this association did not reach statistical significance.

KCC2 heterozygous mice showed a trend toward a higher seizure severity compared to the wild type strain, but it did not reach statistical significance ( z = 0.14).

Stroke volume and heart rate showed a decreasing trend but did not reach statistical significance.

Visual inspection of survival curves also showed a trend toward longer OS of the TNBC subgroup compared to the HR+/HER2− subgroup, but this did not reach statistical significance due to the small number of patients with TNBC (HR, 0.27; 95% CI, 0.06–1.14, p = 0.075).

fT4 was decreased along with a strong trend toward an increase of TRH expression in the PVN that did not reach statistical significance.

While the present study showed a trend toward higher in-patient costs for de Gramont (other than to receive chemotherapy) these differences did not reach statistical significance (de Gramont vs Lokich, mean difference=£874, P =0.181, de Gramont vs raltitrexed, mean difference=£828, P =0.206), although this must be considered in the light of the small sample size.

The 180 day survival outcomes showed a trend towards better results with milrinone, compared with dobutamine, but they also did not reach statistical significance.

Single knockouts showed a trend toward reduced ChAT-positive neurons, though this did not reach statistical significance. dKO mice exhibited significant reductions in NeuN-positive and ChAT-positive neurons (Fig.

Moreover, three studies [ 57 , 61 , 62 ] out of seven showed a significant effect of this intervention in the amelioration of physical performance; the studies that did not reach statistical significance showed a positive trend in the intervention group.

Although the distance traveled in the central zone, time spent in the center, and wall-standing time in the EA-stimulated groups did not reach statistical significance compared with the model group ( p > 0.05), these parameters consistently showed a trend toward improvement ( Figure 2 E–G).

The interaction between Pyk2 and ArhGAP42 phosphorylated at Tyr792 (pTyr792-ArhGAP42) showed an increasing trend upon 60 mM K + stimulation, although this change did not reach statistical significance ( Figure 3 (Ab,Cb)).

Serum decorin levels showed an increasing trend with advancing CKD stage; however, these differences did not reach statistical significance and were not correlated with renal function parameters.

Additionally, BS was associated with a reduced risk of hepatocellular carcinoma (HR, 0.304; 95% CI, 0.099–0.931) and showed a trend toward a lower incidence of liver cirrhosis, though this did not reach statistical significance (HR, 0.865; 95% CI, 0.696–1.075).

Chemotherapy showed a trend towards reduced risk (OR = 0.71, 95% CI: 0.62–1.01), although this did not reach statistical significance ( p = 0.54).

BDNF showed an increasing trend but did not reach statistical significance.

Consistent with previous literature findings, our study showed a trend of elevated PDE4 expression in adhesions from patients with chronic postsurgical pain, although the results did not reach statistical significance.

The PPARα/γ agonist lanifibranor also showed a trend toward reducing SHGS in the GAN-MASH model, although this change did not reach statistical significance (Supplementary Fig. 6D ).

In LIHC, comparison of normal tissues with N0 stage showed highly significant differences, while normal versus N1 stage did not reach statistical significance (Fig. 8 h).

Other interventions—including propofol (MD = −2.1, 95% CrI: −4.3 to 0.082), pethidine plus sedatives (MD = −1.7, 95% CrI: −3.7 to 0.43), and fentanyl plus sedatives (MD = −1.4, 95% CrI: −3.3 to 0.49)—showed a trend toward pain relief, though these results did not reach statistical significance ( Table 1 ).

For progression-free interval, the high-BiScore group also showed an unfavorable trend, although the difference did not reach statistical significance ( Figure 4 D, log-rank p = 0.076).