“did not reach statistical significance”

Although participants with sarcopenia also showed a trend toward an increased risk of CVD compared to those without sarcopenia, this finding did not reach statistical significance (HR 1.01, 95% CI 0.81–1.26).

CBR3 showed a trend towards lower expression in PD samples, though this did not reach statistical significance, which may still indicate a potential role in periodontitis pathogenesis that requires further investigation.

Although the findings did not reach statistical significance due to modest sample sizes (N = 97 for Dutch N = 151 for South Asian Surinamese, N = 328 for African Surinamese, and N = 146 for Ghanaians on CCBs), there was a notable trend.

While individual PAKs did not reach statistical significance in breast and lung cancers, a strong trend in PAK5, similar to prostate cancer was also observed in breast cancer patient survival (Figures 8 and 9 ).

Age at transplant showed a trend but did not reach statistical significance (HR, 1.12; 95% CI, 0.99-1.25; P = 0.06).

Multivariate analysis showed a trend towards lower clearance, but this did not reach statistical significance (p=0.0694).

To the right of the threshold, although a negative trend was observed between serum uric acid levels and femoral neck BMD, it did not reach statistical significance ( β = −0.000, 95% CI : −0.002 to 0.000, P = 0.117) ( Table 4 ).

In the beam walk test, although the results did not reach statistical significance, a decreasing trend in the time to cross the beam was observed (10.3 ± 1.7 for control, 8.6 ± 1.0 for MSC, and 6.2 ± 0.3 for MSC + Ex) ( Figure 2 C). 2.3.

In our study, the OMT group demonstrated significant reductions in the CA index, indicating an improvement in cervical alignment, and although the LA index showed a trend of reduction, this did not reach statistical significance, however.

The results of the meta-analysis were consistent with these findings, with an overall trend toward greater SAF in smokers than in non-smokers for similar age groups, but the difference did not reach statistical significance ( Supplementary Table S7 , Figure S9 ).

A decreasing trend was observed in the Ln LSM values, although these did not reach statistical significance ( Figure 4B ).

The expression of monocyte chemotactic protein 1(MCP-1) and regulated upon activation normal T-cell expressed and presumably secreted (RANTES) was significantly increased in the aortas of KO mice, and that of vascular cell adhesion molecule-1 (VCAM-1) showed a trend of increase in KO mice although did not reach statistical significance ( Fig. 2 G).

Lobule V showed a trend towards smaller volume in CD patients, but the result did not reach statistical significance ( p = 0.082).

In the “good” versus “bad” group comparison, the impact of vegetable intake approached significance but did not reach statistical significance.

All three immunotherapies showed a trend toward improved survival compared to their respective control arms, though the differences did not reach statistical significance.

The intensity of GLuc luminescence in rat blood tends to be higher in the IPP (+) group [IPP (−) vs IPP (+) (AU); 2600 ± 224 vs 2824 ± 241, p = 0.13, Cohen’s d = 0.96]: Although the difference did not reach statistical significance ( p = 0.13), the large effect size in the animal experience (Cohen’s d = 0.96) suggests a notable trend (Fig. 7j ).

Although dehydroepiandrosterone sulfate (DHEAS) showed a trend towards increase, it did not reach statistical significance but was associated with reduced fatigue, a common symptom in MS.

In HER-2-positive and TNBC subtypes, we observed a positive trend suggesting that higher percentages of N20-CD8 + T cells may correlate with better outcomes; however, these findings did not reach statistical significance, possibly due to limited sample sizes (Supplementary Fig. 13 ).

1-year follow-up showed a trend towards reduced NT-proBNP levels in the S/V group, though this difference did not reach statistical significance.

SERCA2a expression showed an increasing trend, while NCX1 expression exhibited a decreasing trend, although these changes did not reach statistical significance ( Fig. 3C, D ).

It is of note that, among the MASLD cohort, there was an overall trend of consuming more refined grains (refined wheat: 0.69 ± 0.99 vs 0.66 ± 0.39 g/kg/d; refined rice: 0.19 ± 0.02 vs 0.13 ± 0.11 g/kg/d) compared with whole grains (wholegrain wheat: 0.23 ± 0.3 vs 0.31 ± 0.34 g/kg/d; wholegrain rice: 0.04 ± 0.12 vs 0.03 ± 0.05 g/kg/d), but the differences did not reach statistical significance.

The post hoc analysis indicated that the LE group demonstrated significantly elevated Sirt1 expression compared to the HE group ( Figure 8 A, p < 0.001) and showed a trend toward elevated expression relative to the CE group, though this difference did not reach statistical significance ( Figure 8 A, p = 0.069).

In the low-dose ACP-60 group (ACP-60-L), the mRNA expression of NLRP3 and Caspase-1 was significantly reduced ( p < 0.05), while ASC mRNA expression showed a decreasing trend but did not reach statistical significance.

In the subsequent years, a segment with a decreasing trend was identified during 2007–2017 with an APC of -10.6 (95% CI, -13.6 - -7.6; p = < 0.001) and another segment with an increasing trend during 2017–2021 with an APC of 7.2 (95% CI, -6.2–22.5), although the latter did not reach statistical significance as indicated by the confidence interval.

Although the overall efficacy improvement did not reach statistical significance, the results suggest a positive trend in favor of OLD for wound management (Table 1 ).