Excerpts

T max of the Loess Plateau in spring showed an increasing trend from 1982 to 2015 and 99.1% of the area showed a significant increasing trend ( p< 0.05), among which 90.9% showed the highest and most significant increasing trend ( p <0.01) ( Fig 2A ).

The C:N ratio had a highly significant ( P ≤ 0.05) positive correlation (R 2 = 0.73) with non-labile-P.

Two other genes, 14-3-3 epsilon (at P7+1d and P7+7d) and FABP7 at P7+1d ( Figure 5 , Table 8 ) were approaching significance (p>0.05 to <0.10). 14-3-3 epsilon increased with a fold change of 1.3±0.1 at P7+1d and 3.1±0.8 at P7+7d compared to age-matched control.

The all-cause mortality were more highly significant than other combinations ( P <0.05) when the following combinations exist: “elevated blood pressure”, “elevated fasting plasma glucose + low high-density lipoprotein cholesterol”, “elevated blood pressure + elevated triglyceride + elevated fasting plasma glucose”, “elevated fasting plasma glucose + low high-density lipoprotein cholesterol + elevated blood pressure + elevated triglyceride”.

We observed that although carriers of AVI/AVI G* (the non-tasters on both individual genes) relative to tasters showed an increase in breast cancer risk, the observed OR did not reach statistical significance at p≤0.05 level (OR = 1.61, 95% CI 0.94–2.77; p = 0.083).

4869 pg/ml; p = 0.1), with borderline significance at 6 hours (3707 pg/ml vs. 3188 pg/ml; p = 0.05).

In the Cox-PH analysis, along with a focused MMS, the ages of the patients at the initial diagnosis and a binary measurement variable indicating the presence of somatic mutation on TP53 gene, which had a modestly significant (p<0.05) effect on the patient survival as shown in our preliminary analysis of the same data, were included as covariates.

Environmental drivers For the Mariana back-arc, the non-linear correlation between habitat area and α-diversity lies on the threshold of significance (Kendall tau, α = 0.05, p = 0.05).

When tested by ANOVAs, VLS was only marginally significant (F = 3.6 P = 0.05), and none of the remaining QTs had significant differences among sites (achromatic F = 2.9 P > 0.05, green F = 0.7 P > 0.05, blue F = 2.8 P >0.05, dorsals F = 0.7 P> 0.05) ( S2 Table ).

Overall, there was not a main effect of group, F( 1, 31) = 0.60, p = 0.71, however the effect of education reached near significance, F (1, 31) = 2.60, p = 0.05.

Although the association of THRIVE with decreased risk of reflux did not reach the statistical difference, a clear trend that THRIVE reduced the incidence of reflux was observed (RR = 0.24, P = 0.05).

The interaction between type of stimulus and form of script was marginally significant ( F (1,31) = 4.08, p≤ .05, η p 2 = .12). t -tests suggested significantly longer reaction times in response to the pointed script only in reading of words ( t (31) = 3.29, p <.01).

Discussion In a population with chronic mental illness, various SNPs in 10 candidate genes ( PPP1R1B , BDNF , DRD3 , DRD2 , HTR2A , HTR2C , COMT , MnSOD , CYP1A2 , and RGS2 ) reached nominally significant (p≤0.05) associations with drug-induced movement disorder.

The expression of SpCRT mRNA at 20°C increased gradually and reached a peak at 12 h before showed a decreasing trend afterward; they were significantly higher than those at 25°C at most sampling points ( P <0.05).

However, a strong trend of improved survival was reported among patients with AA who underwent radical surgery, as opposed to local surgical therapies (HR, 0.71; 95% CI, 0.51–1.00; P = 0.05)[ 6 ].

Secondary ROIs In making all decisions younger pilots showed a trend for greater activity in the bilateral insula (1.36±0.86) compared to older pilots (0.67±0.49; t (17) = −2.17, p = .050).

In addition, a strong trend for reduced volume and cortical thickness was observed for the ERC in the BD patients and the PRC in AD patients (0.005≤ p ≤0.05; Table 3 ).

The main effect of Sex was borderline significant (f(1,25) = 4.28, p = .05, np 2 = .15) with females having a slightly higher SCR ( mean = .46) compared to males (mean = .29).

All tests were two sided with p-value < 0.05 considered statistically significant, p-value < 0.001 was considered statistically highly significant, p-value ≥ 0.05 was considered statistically insignificant.

In both genotypes, these epoxides had a decreasing trend in response to ischemia that was not statistically significant ( P > 0.05; Fig 7A ).

To reduce the multiple testing burden, candidate TFs were tested for interaction with a given gene only if their marginal association with the target probe set was nominally significant ( p <0.05).

There was predominantly a candidate gene approach using common alleles, which despite small sample sizes (median 93 [IQR 40–222]) with no trend to an increase over time, generated a high proportion (74.5%) of nominally significant (p<0.05) reported associations suggesting the possibility of significance-chasing bias.

Statistical significance was determined using an unpaired Student t test and results were considered significant or highly significant when p ≤0.05 or ≤0.01, respectively.

Downregulation of miR-30b was of borderline significance (mean fold-change = 0.86, mean log 2 fold-change = -0.21, sd = 0.47, p = 0.05). miR-483-5p was not downregulated (mean fold-change = 0.93, mean log 2 fold-change = -0.1, sd = 0.97, p = 0.64).

A total of 22 SNPs showed nominally significant association ( p <0.05) with at least one lipid trait in at least one ethnic group, although not always with the same lipid traits reported as genome-wide significant in the original GWAS.