Patients were diagnosed with HNC at a mean of 12.6 years after their diagnosis of RA in the nbDMARD group compared to 12.3 years in the TNFi group; this difference reached borderline significance (p = 0.05).
Excerpts
A chi-square test showed a marginally significant association, χ 2 (3) = 7.8, p = .05.
showed a trendP < 0.05
The α-diversity and NMDS analysis of bacterial community The shannon index and richness index of the total bacterial community increased ( Fig 2A , P < 0.05) with distance from the mining area and reached a maximum at distance H5, while the simpson index showed a trend of increasing and then decreasing, and then reached a maximum at distance H2 (P < 0.05), and was higher than that of H0, although it decreased at distances H3 and H5.
There was also a statistical trend between urgency and EV on percentage bets (F (2,26) = 3.0, p = 0.05).
Only strains from Mallorca and Zaragoza showed a R ST value slightly significant ( P < 0.05).
Although there was a decreasing trend in the IRS-1 mRNA expression level in cells transfected with miR-126 mimic, it did not reach statistical significance between the two groups tested ( P >0.05) ( Figure 3B ).
Concerning the central aspect of fatigue, the SMM did not induce change in %VA for PF ( P = 0.73), but a decreasing trend was observed for KE (−2.18±2.96%, P = 0.05, d = 0.96).
Importantly in CONV mice ileal TNF-α showed strong and highly significant correlation with plasma insulin and plasma glucose (R values: insulin = 0.89, P <0.05; glucose = 0.93, P <0.05) at the 16-week time point ( Table 5 ), and this was a particularly strong correlation.
borderline non-significantp = 0.05
Furthermore, there was no significant difference between the group with metabolic syndrome and controls regarding each criterion of the OA MRI score, with osteophytes being borderline non-significant (p = 0.05).
In addition, rs13017599 in REL was associated (P = 0.03) although the result for this SNP in the whole AAD cohort was only marginally significant at P = 0.05.
The IPAQ scoring did not achieve significance (defined as p<0.05), possibly as it only reflects activity levels.
With Leuppi 2013 included, the mean difference is marginally significant at -0.91 days (95% CI = -1.81–-0.02 days, p = 0.05).
Three additional SNPs from the same intron (rs1071502, rs6497730, and rs1070487) had nominally significant P values for association ( P <0.05), but did not pass the threshold value.
A nominally significant association was observed between survival and the DPP4 enzymatic activity at day 1 (p<0.05), with a higher DPP4 activity being associated with an increase in survival.
In the placebo group, only the gene hsa-miR-9985 was detected to be downregulated upon long-term treatment, with the serum groups showing downregulation of the same gene at a nominally significant level (P ≤ 0.05, FDR > 0.05) after long-term treatment.
The seeds show a decreasing trend in mineral composition as the fruits progress from stage 1 to stage 4, with significant differences (P < 0.05) occurring between these stages for nitrogen, calcium, magnesium, potassium, sodium, manganese, and iron.
Besides rs6697469, there were 2 additional SNPs showed marginally significant association signals with hip fractures, which were rs10917588 ( P = 0.050) and rs7553831 ( P = 0.058).
For our replication of previously reported GWAS SNPs (identified mainly in populations of European ancestry) in our multi-ethnic population, we defined nominally significant as ‘p<0.05 and not corrected for multiple testing.’ Given the different recruitment and BP measurement in the Mt.
Some amino acids, such as proline exhibited a negative trend in their concentrations among subjects with a high GRS compared to those with a low GRS ( p < 0.05) (Table 7 in S1 Appendix ).
The Mantel test confirmed also a relatively strong negative and weakly significant correlation (r = -0.45, p < 0.05) between the genetic distance and cosine similarity, which suggests that the similarity of MOTUs become more dissimilar with increasing distance ( Table 4 ).
P<0.001 was considered extremely significant, P>0.05 was considered non-significant.
The hypothesized occurrence of the supposed recombination event is also supported by the highly significant p -values ( p < 0.05) obtained in the analyses conducting using the GENECONV, Bootscan, MaxChi, Chimera and 3seq bioinformatic software programs.
Meanwhile, when covariates were included, 7,350 genes were nominally significant (p < 0.05), and 5,532 genes remained significant after multiple comparison correction (padj < 0.05).
Having a serious pregnancy complication is associated with higher quality of ANC, but this is only marginally significant (b = 0.22, p = 0.05).
Among the 38 genes in the TRAIL pathway, seven genes achieved nominally significant association with hip OF ( p <0.05); the TNFSF10 ( TRAIL ) gene obtained the most significant p value ( p = 1.70×10 −4 ).