Barely Significant

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Moreover, two recent meta-analyses that were specifically planned to evaluate the hypothesis that variations in the gut microbiota could explain or be used to predict obesity status in humans did not find a clear trend between the F/B ratio and obesity.
Studies were deemed ‘unclear’ if: (1) B12 status did not differ significantly between study groups, or (2) non-specific interventions were used that could obscure the potential effect of B12, or (3) >50% of statistical tests for oxidative stress did not reach significance, but showed an overall trend towards improvement, or (4) ≥50% of statistical tests for oxidative stress were significant, but at least one was significant against the oxidant properties of B12. 3.