However, the ‘transforming growth factor beta (TGF-β)-activated receptor activity’ pathway (GO:0005024) came close to being significant ( P = 9.5 × 10 −6 ) in the combined GERD and BE analysis, followed by the ‘TGF-β receptor binding’ pathway (GO:0005160) ( P = 3.5 × 10 −5 ).
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When adjusting data for predominant motor symptom side, reduced FA persisted in the SN ipsilateral to the more affected body side ( p = 0.034) and a difference in FA in the SN contralateral to the more affected body side came close to being significant ( p = 0.007).
An interaction between change direction and hemisphere only came close to being significant (HS: p = 0.025, CD: p = 0.204, CD *nucl: p = 0.325, CD*HS: p = 0.080, HS*nucl: p = 0.683, CD*HS*nucl: p = 0.853, nucl: p = 0.819, see Supplementary Table 2 for F-statistics).
Nevertheless, in intra-day measurements of A in subjects with keratoconus the correlation was close to being significant (Spearman’s rho = − 0.246, p = 0.03, Kendall’s Tau-b = − 0.162, p = 0.07) (Tables 1 and 3 ).
The results for normalized isometric muscle strength were similar, with a significant interaction-effect for knee flexion ( p = 0.005) and significant time-effects in the intervention group for knee flexion (Δ = 0.19Nm/kg (0.11–0.27), p < 0.001) and plantar flexion (Δ = 0.13Nm/kg (0.08–0.18), p < 0.001) whilst knee extension was close to being significant (Δ = 0.07Nm/kg (0.01–0.13), p = 0.032).
The variable prenatal care had a p-value very close to being significant, being maintained in the model for discussion (p = 0.050).
As for gender differences in overall PE-fit, homogeneity of variance was given, and while the difference between men ( M = 87.06%) and women ( M = 82.53) was only close to being significant, t (86) = 1.98, p = 0.050, a small to moderate effect size of gender, Cohen’s d = 0.437, was found.
Only raw pork and undercooked grilled pork were significant risk factors ( p < 0.05), however, fermented pork was very close to being significant ( p = 0.05).
Age is also close to being significant, with a loading of 0.280 ( p > 0.05).
The surface area was the only other variable that came close to being significant, but it displayed a much weaker correlation with the competitive outcomes (%L: R 2 = 0.09, p -value = 0.05; %W: R 2 = 0.08, p -value = 0.05) ( Fig.
Further, the interaction between pre-intervention discordance and sedentary time was close to being significant (β = −2.64, CI = −5.27 – 0, p = 0.050).
For that reason, we decided to test the Japan data alone for annual seasonality; the result was close to being significant ( p = 0.0505).
There was more haematoma in the treatment group at three days after surgery and this difference was very close to being significant (p = 0.051) (Table 2 ).
In addition, the relationship between employment and chatbot perception is marginally close to being significant (χ 2 8 =15.5; P =.051).
These differences were close to being significant ( p = 0.051 and p = 0.037, respectively). 3.6.
The VEGF mRNA expression level in the normotensive group compared with the early-onset pre-eclamptic group (0.943 ± 0.28) had a p -value very close to being significant ( p = 0.051).
There was only one significant increase in precipitation (Wrocław in March), although that for Rothamsted in August also came close to being significant ( P = 0.051).
The difference was close to being significant ( p = 0.052).
The right lower extremity score was close to being significant ( p = 0.052) when comparing SMotO to barefoot or AFOs but may need a larger yield study to determine its significance and if it is a usual trend.
However, a negative correlation very close to being significant between TGF-β1 concentrations after the 25 th radiotherapy fraction and maximum grades of late GI toxicity was observed ( p = 0.052).
The difference was close to being significant (d = −0.276, 95 % CI – [−0.557; 0.005], t = −3.13, p = 0.052).
For HER2, we saw an upregulation of this receptor in the cancerous tissue that was very close to being significant (p = 0.0520).
Moreover, the impact of exercise training on the composition of the most abundant bacteria was very close to being significant ( P = 0.052 for the Weighted UniFrac analysis).
Regarding regional differences within groups, we found an increase in K v 4.2 (KCND2 gene) expression in the RV of MetS animals ( U = 56, z = 2.522, P = 0.010, r = 0.631) and very close to being significant increase in controls ( U = 40, z = 1.98, P = 0.053, r = 0.530).
The main effect of preference was not significant, χ 2 (1) = 0.720, p = 0.396, while the interaction of preference and effort level was close to being significant, χ 2 (1) = 3.738, p = 0.053, with the slope of the effort predictor however being higher for effort versus reward preferences, t = 1.970, p = 0.049 (see also Fig. 5 a).