In AG if two people showed similar neural patterns in the encoding residual, they were also more likely to tell similar stories (Mean ρ = 0.052, SD = 0.052, z = 2.84, p = 0.004, q = 0.011); The same effect was found in mPFC, but it was only marginally significant (Mean ρ = 0.032, SD = 0.102, z = 1.83, p = 0.066, q = 0.099).
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approached significancep = 0.066
Notably, “Arginine biosynthesis” was similarly upregulated in both CR and DL-fed female 3xTg mice and approached significance in CR-fed male 3xTg mice (p = 0.066), the only pathway so similarly regulated in all four groups.
The results also showed a trend of increased neutrophils in the microenvironment, although this trend along the stage progress were marginally significant (trend test, P = 0.066; Fig. 7c ).
5b ), and even if only with a marginal trend, their decline was also stronger at the rear than at the leading edge (Time × Elevation p = 0.066).
In PPC, a strong value effect was found ( t (17) = 4.27, p = 5.8e−4), while the saliency predictor was marginally significant ( t (17) = 1.97, p = 0.066).
In this condition, a decreasing trend in the EMG REM/NREM ratio was also observed (EMG REM/NREM ratio; light-off: 0.94 ± 0.01, light-on: 0.91 ± 0.02; n = 9 orexin ChR2 mice; P = 0.0662) (Fig. 6i ).
showed a trendp = 0.0663
Furthermore, the expression levels (median signal intensity, MSI) of CD57, a marker for terminal differentiation, among CD8 TEMRA showed a trend to be increased ( p = 0.0663) in PD (Fig. 1g ).
marginally non-significantP = 0.067
A similar pattern was observed if only top predators were evaluated, though with marginally non-significant results (top predators; P = 0.067, Table 1 , Supplementary Fig. 2 ).
showed a trendp = 0.0671
In contrast, female plKO microglia showed a trend towards an increase in Mbp mRNA within sorted microglia at P7 ( p = 0.0671).
In contrast, related pairs showed a numerically negative asymmetry value; however, despite a moderate effect size, this effect was only a nonsignificant trend after corrections for multiple comparisons ( t (79) = 2.157, p = 0.068, d = 0.49, 95% CI = [−0.049 −0.001]).
a trend toward significancep = 0.068
In this model, TP53 mutations remained independently associated with poorer DSS (HR: 3.33, 95% CI: 1.21–9.12, p = 0.019), whereas metastatic status showed a trend toward significance (HR: 2.95, 95% CI: 0.92–9.40, p = 0.068).
We further found a borderline significant effect of the ORAI2 editing event on the protein expression of MAPT ( P = 0.068) (Fig. 6f ).
In terms of biomass proportion within the total understory community, increases in shrub biomass proportion decreased significantly with increasing cumulative nitrogen deposition ( P = 0.002), but showed a marginally significant increase in response to rising temperatures ( P = 0.069) (Fig. 3 d, Supplementary Fig. 3b , Supplementary Table 2 ).
showed a trendp = 0.0698
For Barnes maze, analyses included all groups (sham, SDV, SAP, and CCK-SAP) and revealed that (1) dorsal HPC BDNF levels are negatively correlated with average error difference (T2–T1) (F[1,28] = 4.211, R2 = 0.1307, p = 0.0496) and (2) dorsal HPC DCX levels showed a trend toward significant correlation with Barnes performance (F[1,29] = 3.546, R2 = 0.1089, p = 0.0698).
As such, 12 to 72 tests (median of 12) were conducted per literature association, and we classified as “marginally significant” those associations with KW p value between 0.05 and 0.001 (nominal p value of 0.001 with 72 tests yields a Bonferroni-corrected p value ~0.07).
forgotten: t (17) = 2.48, P = 0.02, CI: [−0.14–(−0.01)], Cohen’s d = 0.58; approaching significance for n-PK pairs, remembered vs. forgotten: t (17) = 1.92, P = 0.07, CI: [−0.008–0.17], Cohen’s d = 0.45).
borderline non-significantp -value = 0.07
unsolved HRD cases showed borderline non-significant enrichment for rs118031911/T in unsolved cases ( p -value = 0.07, OR = 2.30, CI = 0.94–6.76, by Fisher’s exact test), possibly indicating that either well-defined triallelism does not take place for this variant or that we did not have enough power to detect it.
showed a trendP = 0.07
miR-143/145 +/− marrows also showed a trend toward reduced LT-HSC ( P = 0.07). miR-143/145 −/− and miR-143/145 +/− mice had similar marrow cellularity to WT mice suggesting a deficit in absolute number of HSC (Fig. 1b ).
In contrast, there were significant correlations between histological abnormalities in the large intestine and reduced infant macaque growth kinetics including the cecum ( P = 0.02), ascending colon ( P = 0.02), transverse colon ( P = 0.03), descending colon ( P = 0.07; trending towards significance), rectum ( P = 0.004), and the large intestine in total ( P = 0.01) 20 .
This trend reached near significance ( P = 0.07, exact Wilcoxon test) in groups administered with CH505 sequential gp120 Envs when they were formulated in AS01E ( N = 8), with mean autologous tier 1 (CH505.w4.3)-neutralizing antibody ID50-titers of 2264 ± 2932, relative to those administered with CH505 TF Env gp120 alone formulated in AS01E ( N = 8), which by comparison, induced mean autologous tier 1 (CH505.w4.3)-neutralizing antibody ID50-titers of 630 ± 383.
To independently confirm this, we performed a one-way analysis of variance (ANOVA) on the TDA-identified subject subsets, confirming significant drug effects on MN sparing ( P =0.02) and tissue area at the epicentre ( P =0.002), with other outcomes approaching significance, including grooming at 28 days post lesion (DPL) ( P =0.07).
After adjusting for sex, this association remained nominally significant (HR = 4.48 [0.90–22.23], p = 0.07), consistent with our findings showing MS3 as at higher risk of MI (Fig. 4D ).
Below 4100 m, E SMR demonstrated an increasing trend with elevation (approaching statistical significance, P = 0.07), whereas above this threshold, E SMR remained relatively stable with minimal and statistically insignificant variation.
In addition, correlation analysis of the dataset revealed a positive trend between Bmal1 and Dpp4 expression across time points (r2=0.142, P = 0.070).
Moreover, we observed a marginally significant ( p = 0.07, Mann–Whitney test) difference in the number of DRMs of NS3-specific DAAs (4–10) and multi-protein DAAs (8–16).