Excerpts

In the jejunum, APN activity per unit length was significantly higher in the LP group than in the EF group and showed a trend toward being higher than in the AC group ( p = 0.09) ( Figure 1 C).

Within the CA1, the effect of injury was approaching significance in terms of integrated density ( p = 0.0907) ( Figure 5 B) but not area fraction ( Figure 5 C).

These ML B2/PNI− tumors had a significantly worse disease-specific survival (DSS, HR = 2.288, p = 3.8 × 10 −2 ) and showed a clear trend towards unfavorable overall survival (OS, HR = 1.711, p = 9.1 × 10 −2 ) and progression-free interval (PFI, HR = 1.669, p = 1.1 × 10 −1 ) compared to ML A/PNI− tumors ( Figure 3 D).

Patients with a high RAS allele frequency, defined as Variant Allele Frequency (VAF) > 20%, showed a trend for lower survival rates with a median OS of 30.95 months (95% CI 18.2–47.4) compared to 37.42 months (95% CI 26.97–NR) for patients with low VAF ( p = 0.091; HR = 2.13, 95% CI 0.89–5.09). 3.

Post hoc analysis showed that (a) patients with LELC had better survival than patients with MBCMD ( p = 0.0027) (b) patients with LELC had no difference in survival compared to patients with BCOGC ( p = 1) (c) patients with LELC had better survival from patients with SRCC ( p = 0.009) (d) patients with MBCMD had worst survival from patients with BCOGC ( p = 0.0027) but (e) no difference was confirmed when compared to patients with SRCC and finally (f) a marginal significance ( p = 0.091) was detected when comparing patients with BCOGC with those having SRCC the latter having worst survival probability.

Conversely, the comparison with the Tuscan population only showed a trend toward significance (Allele dominant, OR, p = 0.0915; Chi-square, p = 0.874; Allele contrast, OR, p = 0.0938; Chi-square, p = 0.0929).

Our meta-analysis of high quality RCTs did not show any effect on percent fat or fat mass, though a marginal trend ( p = 0.092) for BMI to decrease with increasing vitamin D status was noted.

Multivariate analysis showed a trend for GLIS1 expression as an independent indicator for OS (HR = 0.157, p = 0.092) ( Table 4 ).

The present study found a numerically higher improvement in peak VO 2 in favor of the exercise group, with a tendency toward statistical significance ( p -value = 0.092).

In addition, a higher close-to-significant expression of DUSP6 ( p -value = 0.092) was observed in patients with stages III/IV ( Supplementary Table S4 ).

However, marginally non-significant associations were observed for the CGC haplotype regarding the PWV/GLS ratio variation during the observation period ( p = 0.092), the CGC haplotype with TAPSE at six months ( p = 0.101), and the TGC haplotype with IMT variation during the observation period ( p = 0.055).

The Level of Epinephrine and Nor-Epinephrine in the Dorsal Hippocampus in Adult and Middle Aged WT and GPR37L1KO Male and Female Mice after PAT A three-way ANOVA for the level of epinephrine in the dorsal hippocampus revealed a significant effect of sex [F (1,46) = 12.60, p = 0.001; Figure 5 A], and a trend towards significance for genotype [F (1,46) = 2.94, p = 0.093; Figure 5 A], with no significant effect observed for other factors ( Figure 5 A).

Although there was no notable difference, the sum of PC-OOH showed an increasing trend in the oxLDL-supplemented cells (Con. vs. oxLDL, p = 0.093; nLDL vs. oxLDL, p = 0.103) ( Supplementary Figure S12D ).

Fisher’s exact test on adequate samples showed a trend toward association ( p = 0.093), though this did not reach statistical significance due to the limited number of mutation-positive cases.

Compared to CON mice, a clear trend towards increased rectal temperature was observed in SUC mice ( p = 0.094), whilst SUC + PHE mice showed a significant higher rectal temperature.

Differences in RANK expression between histological grade II and grade I tumors were of borderline significance ( p = 0.094).

NIR significantly enhanced fusion relative to both the control ( p = 0.014) and LED ( p = 0.047), while LED treatment alone showed only a nonsignificant trend toward improvement compared with the control ( p = 0.094).

The near-significant trend observed for XDH ( p = 0.094) might indicate a weak endogenous rhythm, consistent with its antioxidative role and earlier studies describing partial circadian control of redox enzymes such as superoxide dismutase, catalase, and glutathione peroxidase [ 9 , 65 , 67 ].

Supplemental VC showed a trend towards increasing body weight gain (BWG) at 21 d ( p = 0.094), increased breast muscle rate (at 21-d 5.33%, p < 0.05 and at 42-d 7.09%, p = 0.097), and decreased the abdominal fat (23.43%, p < 0.05) and drip loss (20.68%, p < 0.05) at 42-d.

That frequency was almost significant when considering the tumor differentiation grade (differentiated, moderately differentiated, and poorly differentiated; p = 0.095) but no differences were found between the anatomic location of the tumor (proximal, distal, rectal; p = 0.437).

These values were significantly higher than those at the 30 min time point ( p < 0.01), and linalyl acetate in the 10% group showed a near-significant difference compared to the 5% group at 60 min ( p = 0.095).

Moreover, compared with the protein group, additional omega-3 supplementation in men resulted in significantly reduced CCL-2 ( p = 0.004) and HMGB-1 ( p = 0.001), and also showed a trend towards decreased IL-6 ( p = 0.095) ( Figure S1 ).

A significant increase was observed in hippocampal Ccl21a expression ( p = 0.02, Mann–Whitney test) in Figure 4 in the old mice compared to the young mice, as well as a strong trend for increased expression in the prefrontal cortex ( p = 0.095, Mann–Whitney test).

Androgen receptor (AR) expression showed a positive trend with the resorption marker CTX-I ( p = 0.0956).

Also, a statistical trend was noticed in CD4 and PD-L1 distribution between these groups where tumors with high CD4 infiltrate and positive PD-L1 did not have metastasis/recurrence ( p = 0.096 and p = 0.065, respectively) ( Table 4 ).