Excerpts

There was a correlation of borderline significance (CC = 0.152, p = 0.059) between Siglec-8 expression and tumor grading (G).

RT-PCR revealed that BTG1 siRNA-transfected cells exhibited 1.18- and 1,94-fold increases in MMP2 and MMP9 mRNA expression levels compared to vehicle-treated control cells, with marginal significance ( p = 0.059 and p = 0.089, respectively; Figure 2 B).

In our study, the MMP-1 rs1799750 1G2G genotype (compared to 2G2G) showed a trend toward increased arterial thrombosis risk (OR = 3.200, 95% CI 0.956–10.714, p = 0.059), indicating a possible association that warrants further investigation in larger cohorts.

Moreover, CCL11 was among the top core enriched genes with respect to angiogenesis in the non-inflamed UC mucosa, with a borderline significant upregulation (FDR; p = 0.059), but significantly upregulated in the inflamed UC mucosa, and present in a IBD GWAS loci.

Dup: p = 0.045), with dupilumab achieving a near-significant reduction (median −0.7 pg/mL, 95% CI: −1.5, 0.0, p = 0.059).

This near-significant difference ( p = 0.059) suggests that FSHR expression may be more pronounced when an ovarian cycle is allowed to progress without pharmacological suppression.

Moreover, ovarian cancers that were triply positive for intraepithelial CD4 + , FOXP3 + , and CD25 + cells showed a trend towards increased survival ( p = 0.059) [ 55 ].

PD-L1 expression has, also, significant impact on overall survival (OS) ( p = 0.045), while for PD-1 expression only a positive trend was seen for OS ( p = 0.059) [ 36 ].

No effects were observed for groups, but there was a clear trend showing higher GR-positive cells in the PSS-exposed groups (F(3, 52) = 2.6, p = 0.059).

Two-way ANOVA of the data indicated a nearly significant effect of genotype on the percent active responses (F 1,19 = 4.02, p = 0.059).

A two-way ANOVA on synaptic density indicated a trend toward significance on ketamine (F [1, 33] = 3.798, p = 0.059) but not CHIMERA (F [1, 33] = 1.193, p = 0.283) as shown in Figure 4 F.

We detected a nearly significant decrease in the apoptotic level of 42.5% (0.4188 vs. 0.7286, p = 0.059) after the injection of exosomes from SI (0 Gy).

Significant main effects of sex ( p < 0.0001) existed for all four muscles, while a main effect of tumor group only existed for the EDL muscle ( p = 0.0011) and approached significance for the Tibialis Anterior muscle (TA; p = 0.0592), representing lower muscle weights in tumor groups.

Formaldehyde also exhibited a decreasing trend that approached borderline significance ( p = 0.06).

Conjunctival Antigen-Presenting Cells The percentage of bone-marrow-derived CD45 + cells in the conjunctiva obtained by impression cytology from all three sites—superior bulbar (SB), nasal bulbar (NB), and temporal bulbar (TB)—was significantly higher in the KCS group ( p < 0.02) and approached significance in cells obtained from the SB alone ( p < 0.06).

Examination of the model investigating the statistical interaction between STAT1 and TGFB2 showed that there was a borderline significant increase in HR for the TGFB2 high group of patients (HR (95% CI range) = 1.84 (0.97–3.46); p = 0.06) There was a significant increase in HR for the STAT1 high group of patients (HR (95% CI range) = 2 (1.08–3.71); p = 0.029), accounting for significant impact of age at diagnosis (HR (95% CI range) = 1.03 (1.01–1.05); p = 0.005).

A subgroup analysis by onset type showed a trend toward a benefit in patients with limb onset (74% vs. 51%, HR 0.5, p = 0.06), while patients with bulbar onset showed no benefit (44% vs. 62%, HR 1.66, p = 0.36).

Omega-3 FA supplementation resulted in a numerical reudction in the fibrotic area, exhibiting a marginal trend toward statistical significance ( p = 0.06). 2.2.

In our EpiPath cohort, there was a strong ELA-associated increase in immunosenescence-associated chronic inflammation, together with increased T h 17 cell numbers, although this narrowly missed significance ( p = 0.06, [ 51 ]).

At baseline, patients with severe PASI (>10) showed a trend toward higher expression of CXCL10 ( p = 0.060) and CXCL9 ( p = 0.060) in NL skin compared to those with mild PASI (≤10) ( Figure 2 D).

Similarly, ex vivo samples from IRL201805Res patients revealed a strong trend ( p < 0.06) at 72 h for greater intracellular expression of IDO when compared with Pbo at the same time-point.

non-injured p = 0.031; Figure 7 B) and a trend toward significance in the caudal zone at 7 dpi (F 2,6 = 4.48, p = 0.06; Tukey test p = 0.051; Figure 7 B).

Notably, for the aif1 gene, the treated AD mice showed a trend toward less gliosis compared to non-treated mice ( p = 0.06). 3.

It is also noteworthy that the interaction between DHT treatment and litter size reduction is on the brink of significance for pAMPK-Thr172/AMPK ratio (F (1, 20) = 3.87, p = 0.06).

The expression of LRb transcripts in the VMH/DMH was not significantly different between sheep groups; however, a trend close to significance ( p = 0.06) was observed in the Lean-R group.