TMB level was lower in ICI-resistant patients than in ICI-sensitive patients with a trend close to significance (median TMB 20.8 vs 29.3 mutations/Mb, p=0.051) ( figure 4A ), while no significant difference was found in the rest parameters ( online supplemental figure 8 ).
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ABS–A reduction in strength of −2.9 MPa, with a trend close to significance ( p = 0.0529).
In addition, long jump showed significant Poisson regressions, while triple jump showed a trend close to significance ( p = 0.054).
Although the Barthel Index [ 26 ] showed a trend close to significance ( p = 0.0545), it did not reach the conventional statistical threshold, so it is recommended to evaluate this possible pattern in studies with larger sample sizes. 4.
There was a trend close to significance for a longer metastasis-free survival in patients with low phosphorylated Smad2, corresponding to a sum score lower or equal to 3 (p=0.055) (Figure 2 D).
When analyzing the different delays, an effect of group was detected in the 6 s delay (F 1,35 = 4.198; p < 0.05; partial η 2 = 0.107), as well as a trend close to significance in the 12 s delay (F 1,35 = 3.885; p = 0.057; partial η 2 = 0.1), but no effect was noted in the others.
A trend close to significance was found in RAVLT-I, in which ET-RBD patients performed worse (p = 0.060).
A two-way ANOVA showed a trend close to significance for the object effect ( F 1, 18 = 4.01, P = 0.06) and genotype × object interaction ( F 1, 18 = 4.20, P = 0.055).
The expression of LRb transcripts in the VMH/DMH was not significantly different between sheep groups; however, a trend close to significance ( p = 0.06) was observed in the Lean-R group.
Of course, the variable left chest pain showed a trend close to significance (p=.066).
In addition, the concurrence of pre-existing CLD might be a potentially relevant factor with a trend close to significance for fatal outcomes of HILI (p=0.078).
However, a comparison between WL and FF conditions showed a trend close to significance [ t (10) = 1.961; p = 0.078].
A trend close to significance was apparent for type 2 diabetic patients (p = 0.08) and with airway obstruction (p = 0.11).
Statistical analysis of clinical characteristics showed that high DDR2 expression was highly correlated with lymph node metastasis ( p =0.037) and positively correlated with clinical stage at a trend close to significance ( p =0.082, Supplementary Table 1 ).
The AR-V7-positive patients exhibited a significantly higher proportion of any site metastasis (61.3% versus 35.0%; OR 2.19, 95% CI 1.57–3.05, p < 0.001) and bone metastasis (81.7% versus 69.0%; OR 1.97, 95% CI 1.44–2.69, p < 0.001), and a trend close to significance was expected in visceral metastasis (28.8% versus 22.1%; OR 1.29, 95% CI 0.96–1.74, p = 0.09).
Although no statistical significance was achieved in the χ 2 test (χ2 = 2.949; P = 0.086), the Fisher exact test showed a trend close to significance ( P = 0.097).
PCT had a trend close to significance to be lower for children with VUR ≥3 in the validation set compared with those in the derivation set: median = 1.5 ng/mL (IQR: 0.3–6.1) vs. 2.9 (IQR: 1.2–6.8); P = 0.06.
Hospitalizations for acute coronary syndrome decreased only during the final smoking ban (period 4), where we measured a trend close to significance: adjusted IRR was 0.90 [95%CI: 0.80–1.00] for all patients and 0.89 [95%CI: 0.78–1.02] for Geneva residents ( Table 2 ).
The average HOMA values were higher in the PCOS group, with a trend close to significance.
45 , 46 The analysis of the correlations demonstrated a trend close to significance between obsessions and compulsions, namely aggression, and symmetry/ordering/rearrangement in the BU-OCD group.
Additionally, knockdown of DNM2 also significantly increased the proportion of late apoptotic cells in the presence of bortezomib and sEVs, and CLTC knockdown induced the similar effect with a trend close to significance (Figure 6 J-K).
Interestingly, the LH response during the GnRH test was correlated to the basal AMH level in the whole group of patients with FHA, with a trend close to significance in those with PCOM, contrary to patients without PCOM.
Moreover, the MM burden was positively correlated with the frequency of CD8 T cells in MM patients and negatively correlated with the frequency of CD16 + NK cells with a trend close to significance (Supplementary figure 2 b).
However, proportional deviation from covariation plane evaluated by PV3 demonstrated a trend close to significance showing a better plane fitting after HAL therapy for acute but not for chronic group; quantitative comparison between PV3 before and after HAL therapy were close to significance for acute group only (Figure 3D , PV3 mean acute-pre: 0.03 ± 0.01, acute-post: 0.02 ± 0.007, chronic-pre: 0.013 ± 0.009, chronic-post: 0.012 ± 0.009.
13 As in the ARCTIC cohort, no sex-differences were found for lung cancer prevalence, 34 despite a trend close to significance for lung cancer in deceased patients in our study.