Excerpts

The best result achieved for correlations between MC and the theoretical composition was a tendency toward significance (Spearman = 0.67, P = 0.07) when 20 PCR cycles were used in combination with the V4 primers.

wild type) in colony frequencies and an increasing trend (average caspofungin resistant colony frequency = 2.17E-7 ± 7.65E-8 and 1.98E10-7 ± 1.04E-7; P = 0.07 and P = 0.06, respectively).

In our samples, Simpson indices indicated that alpha diversity increased in the presence of plants, yet with marginal significance ( P = 0.07).

Notably, the Bite + DSS group showed a trend toward less weight loss compared to DSS-only mice during recovery ( p = 0.07), suggesting possible modulation of disease course by bite exposure.

Compared with the control group, the antioxidant enzyme activity in the tissues from gilts in the HMSeBA group was increased, and the concentration of malondialdehyde in the colon had a decreasing trend ( p = 0.07).

In contrast, MAA fold change showed a positive trend with ΔY(II) ( ρ = +0.77; p ≈ 0.07–0.08), where species with low constitutive MAA levels but strong inducible increases also displayed larger declines in Y(II).

A similar pattern was observed in monoculture plates, however this was only marginally significant ( p = 0.07, Figure 5A ).

In fact, PathoScope was significantly similar to the added proportions in Control A ( p = 0.041), and approached significance in Control B ( p = 0.071).

The diet × time of sampling interaction was significant for Dialister ( P < 0.01) and unclassified Lachnospiraceae ( P < 0.05) and showed a tendency toward significance ( P = 0.072) for Syntrophococcus .

However, effects of spider mite infestation on bacterial community composition were marginally significant ( R 2 = 0.02, pseudo-F = 1.03, P = 0.072; Figure 6 ).

Interestingly, contrary to the 16S rRNA sequencing results, the qPCR results for Day 6, fecal-Chx versus fecal-Mck samples only approached significance ( p = 0.072823) reflecting the specificity of this targeted quantitative assay.

The difference in acetate concentration between the groups was not significant ( p = 0.183), though the difference between the S1 and S3 groups tended toward significance ( p = 0.073).

The total net effect of water addition on the bacterial community was marginally significant [standardized coefficient = 0.28, Z value (dividing the regression weight estimate by its standard error) = 1.79, P = 0.073], whereas that of nitrogen addition was non-significant (standardized coefficient = 0.11, Z value = 1.35, P = 0.176).

Although we did not find a significant correlation between seed mass and swainsonine concentration in S+ species, there is a positive trend that might become stronger with increased sampling ( p = 0.075, Supplementary Figure 4 ).

Results showed that YC supplementation significantly increased the hatching rate, showing an evident trend, thus augmenting the rate of fertilization ( P = 0.075) and number of healthy chicks ( P = 0.064).

Additionally, both the operative and appropriate empirical treatment showed borderline significance with the ST11 CRKP infection ( p = 0.075 or p = 0.056, respectively).

Several near-significant associations in DHCCs included negative correlations between the PPAR signaling pathway and platelet count ( r = −0.47, p = 0.075) and between secondary bile acid biosynthesis and the international normalized ratio (INR) ( r = −0.58, p = 0.023). 4 Discussion Hepatocellular carcinoma in patients with diabetes mellitus represents a growing global health challenge, with emerging evidence suggesting that the gut microbiome plays a pivotal role in disease progression ( Dorrah et al., 2025 ; Ma et al., 2025 ).

Quantitative analysis showed a trend toward improved hepatic perfusion following healthy-donor FMT that did not reach statistical significance ( p = 0.0754).

A redundancy analysis (RDA) on the OTUs level was performed and no significant differences were found in the microbial populations according to the BMI, only a negative trend could be observed ( P = 0.076).

There was a decreasing trend in terms of fungal richness ( p = 0.0774) (Figure 4 ).

Crypt depth showed an increasing trend due to the synbiotic administration on day 4 PI in the Salmonella trial ( p = 0.078), but, contrarily, a decreasing one on day 3 in the ETEC F4 trial ( p = 0.081).

Isoleucine levels were highest in the BCAA group, with a trend toward significance ( p = 0.078; Table 4 ), likely reflecting the supplementation of branched-chain AAs in this group.

There was also a weak trend toward positive correlation between plasma levels of vWF and sCD14 ( p = 0.078; r = 0.184, Figure 5D ).

Epibiont assemblages in cultured and environmental Chaetoceros cells also differed significantly as determined by culture-based approach ( P < 0.001) while molecular libraries showed only marginally significant difference ( P = 0.079) (Figures 1E,F ).

The regression between respiration rates and distance from the nearest shore was marginally significant: ln(Respiration) = −2.648 + 0.559[ln(Distance)], Adjusted R 2 = 0.046, p = 0.079 (Figure 2 B).