Excerpts

Given this premise, they found a favorable trend for systemic treatment compared to RT in the inoperable group ( p = 0.083).

Although pCR rates were consistent with our current results, this study showed an unfavorable trend for CROSS compared to PF (MST 32.7 versus 16.7 months, respectively, p = 0.083).

WF-ORI imaging showed a trend towards an increase in ΔORR (i.e., treatment resistant) between control and FOLFOX-treated PDCOs ( p = 0.083; Figure 3 A).

Tumor samples with Periostin high FAP low PDGFR low SMA high just showed a trend for a worse overall survival ( n (low) = 15, n (high) = 16, p = 0.083, Figure 2 B).

Notably, the impact of PSMA PET-CT staging on BRFS was marginally significant in the univariate analysis (hazard ratio (HR) 0.428, p = 0.083, 95% confidence interval (CI) 0.159–1.150). 3.5.

Additionally, sVCAM-1 showed a trend towards reduced cachexia risk ( p = 0.083).

Median OS was 81.2 months; NSND showed a trend toward improved OS ( p = 0.083) and improved OS after age/sex adjustment (HR 0.64, 95% CI 0.42–0.98), but not after full clinicopathologic adjustment; DSS did not differ ( p = 0.59).

In our series, lymphocyte levels below 1000/mcl were associated with borderline significance with a lower LRPFS in the HPV-positive subgroup ( p = 0.084, results not shown).

Additional exploratory analyses showed a trend toward higher prevalence of TP53 pathway alterations in Hispanic/Latino EOCRC patients (OR = 2.13, p = 0.084) and identified sex-based disparities in treatment, with women being less likely than men to receive FOLFOX (OR = 0.845, p = 0.0138).

The univariate analysis (see Supplementary Materials ) showed that the two variables, Vascular Invasion and Cribriform, were significantly associated with survival outcomes ( p < 0.05), while the variable Stage was marginally significant ( p = 0.084).

Although non-significant, the combination treatment showed a trend of improved DFS compared to the no-treatment control ( p = 0.084) ( Figure 5 B).

Histological type showed a trend toward significance, with squamous histology associated with a higher hazard than adenocarcinoma (HR = 2.58, 95% CI: 0.92–8.33; p = 0.0849).

In the whole group, the MMP2 rs7201 C variant conferred an increased risk of locoregional recurrence ( p log-rank = 0.025, HR 1.55, p = 0.037; Figure 1 I), while the association of TIMP2 rs7501477 T allele with poor LRFS was only marginally significant ( p log-rank = 0.068, HR 1.40, 95% confidence interval (CI) 0.95–2.07, p = 0.085.

Subgroup analysis revealed a positive trend in reflux symptom management in the WECARE group ( p = 0.0856).

Binary category analyses indicated a marginally significant relationship between TPM status and longer telomeres ( p = 0.086), and changes in expression of miR449a ( p = 0.157), HDAC4 ( p = 0.146) and HDAC9 ( p = 0.149).

Muscle Strength, Cardiorespiratory Fitness, and Resting Metabolic Rate No significant changes in chest press strength ( p = 0.745) or seated row strength ( p = 0.744) were observed; however, leg press strength approached significance ( p = 0.086) with a 6.1 kg increase reported across the home-based program ( Table 4 ).

In multivariate analysis (Wald test; Table 2 ), two variables (pN and TN subtype) remained significant, whereas the 70-gene signature tended towards significance ( p = 0.086), and the prognostic value of XIAP was maintained (HR = 1.67, 95%CI 1.20–2.31, p = 2.07 × 10 −3 , Wald test), suggesting independent prognostic value.

Here, CD3 density and PD-1 expression in both tumor areas (CT, IM) showed a significant impact on both DFS and OS (CD3: CT, p = 0.018/IM, p = 0.002 and PD-1: CT, p = 0.037/IM, p = 0.016, respectively), whilst PD-L1 expression showed a trend towards improved survival (PD-L1: CT, p = 0.087/IM, p = 0.078); with regard to CD8 density, only expression in the IM was associated with improved survival.

In the Revised T category, the five-year cumulative OSR of T2 and T3 showed marginally significant differences (40.6% vs. 26.9%; p = 0.087) ( Figure 1 c). 2.3.

Although 16S rRNA sequencing data showed a trend towards more non-aerobic bacteria in BIA-ALCL compared to the benign seromas, this difference did not reach statistical significance ( p = 0.087) ( Figure 6 ). 4.

HBV viral factors were not significantly different among groups with or without recurrence, despite the presence of HBV genotype C, indicating a slight trend toward HCC recurrence ( p = 0.087).

Figure 5 B shows an increasing trend in mortality risk for primary tumor patients when mut_coding variants were present ( p = 0.087).

Survival analyses of our patient cohort showed that patients with CSCC had a better disease-free survival compared to patients with CAC, although the difference was at the limit of significance ( Figure S1 , p = 0.088). 3.4.

Regarding margin status, R0CRM− resection was achieved in 17 MP-positive cases (61.3%) and 15 MP-negative cases (88.2%), indicating a statistical trend ( p = 0.088). 3.4.

≥70 years) ( Supplementary Figure S2 ) showed a trend toward significance for OS ( p = 0.088), while no significant difference was observed for PFS ( p = 0.337).