When patients were matched for symptom duration (GA n=11, ACAA n=17; median 8 years from symptom onset to MR; mean age 52±7 years for both groups; mean ataxia severity GA=1.6, AA=1.5) there was an overall trend for reduced vermian NAA/Cr in the GA group compared to ACAA but this failed to reach statistical significance (0.79 vs. 0.87 respectively, CI 95% -0.19 to 0.03, p>0.05).
Despite showing a numerical trend toward better overall survival, TMB failed to reach statistical significance at both timepoints (median follow-up period of 23.5 and 35.5 months) ( Figures 3A, B ).
There has also been observed a decreasing trend in time in m-Ins, but it failed to reach statistical significance (F = 2.84, p = 0.07).
Interestingly, Mlkl knockdown surprisingly promoted macrophage lipid accumulation and was associated with a weak trend toward increased early atherosclerotic lesion size, although this trend failed to reach statistical significance.
The entry of ANS accuracy and Weber fraction in Step 3 also failed to reach statistical significance, Δ F (2, 41) = 2.88, p = 0.068, Δ R 2 = 0.022, although the increment approached significance.
In the Würzburg/Berlin sub-cohort of COVIDOM, pre-existing neurologic or psychiatric diseases were also found to be a highly significant predictor of the PCS-S score, but the same association failed to reach statistical significance in Kiel-II after adjustment for multiple testing.
All other specialty-specific analyses failed to reach statistical significance due to limited case numbers, but showed a trend consistent with the overall cohort findings.
Measurements of neutrophil and systemic activation Expression and regulation of L-selectin Examination of the basal expression of L-selectin on neutrophils showed a trend towards lower expression in patients with RA; however, this marginally failed to reach statistical significance ( p = 0.07; Figure 2a ).
A decreasing trend was observed in the patients' body mass index, but it failed to reach statistical significance (p value = 0.063).
Concurrently, a positive trend was observed between increasing medication count and impairments in locomotion, nutritional risk, and hearing, although these associations failed to reach statistical significance.
In contrast, antigen-exposed transgene-negative animals showed a trend to increased right ventricular systolic pressures that failed to reach statistical significance ( Fig. 2 ).
The disease incidences in 2020 of IIM (RR, 0.473; 95% CI, 0.307 to 0.697), SLE (RR, 0.845; 95% CI, 0.798 to 0.895), and BD (RR, 0.850; 95% CI, 0.796 to 0.906) were significantly decreased compared with that of the previous 4 years, whereas the annual incidence of gout (RR, 1.012; 95% CI, 0.916 to 1.117), PMR (RR, 1.075; 95% CI, 0.928 to 1.239), and hypertensive diseases (RR, 1.023; 95% CI, 0.929 to 1.124) exhibited an increasing trend that failed to reach statistical significance.
In neurological patients, CV con demonstrated a positive trend, but failed to reach statistical significance (subtotal HR = 2.21, 95%CI = 0.69–7.11, p = 0.181), with significant heterogeneity ( I 2 = 96.5%, p < 0.001).
In phase II clinical trials involving 285 RA patients, VX-740 showed a trend toward symptom improvement but failed to reach statistical significance.
Results: Better performances were noted by both observers in group B only regarding “Respect for tissue” scores (3.75±0.16 vs 4.43±0.20, P=.021 and 3.87±0.22 vs 4.57±0.20, P=.041) achieving significant or marginally significant differences for all categories; GRS scores for “time and motion” and “overall impression” tend to be better after warm-up, but differences failed to reach statistical significance in our series.
Of the haematological parameters assessed only preoperative platelet count showed a strong trend of association with disease free survival; however this failed to reach statistical significance ( P = .076).
Higher numbers of ICD shocks showed a trend toward increasing the OR of GAD, MDD and PTSD, but failed to reach statistical significance as well as sex and educational status.
Compared with the OBJ-NSR task, the POR-MUS group showed a trend toward mild deficits that failed to reach statistical significance.
59.7%) showed a strong trend towards the failure of TVB but failed to reach statistical significance after using correction for multiple testing ( p = 0.06).
For the subchondral bone a strong trend for increased mRNA was found for CCL2 at day 14 which narrowly failed to reach statistical significance.
They observed the efficacy of the MPC-based CDSS in 9 patients, and the results showed that the on-target rate (Hb 10-12 g/dL) had an increasing trend and that ESA dosage had a decreasing trend, but both parameters failed to reach statistical significance.
VSVG-pseudotyped vectors showed a trend toward higher CD8 T cell frequencies after booster vaccination, too, but these differences failed to reach statistical significance.
Promoter-associated CpG sites of the imprinted Airn gene, encoding an antisense regulator of Igf2r , showed a trend towards demethylation, which might be hyperproliferation-associated, but this failed to reach statistical significance.
The verbal revision had a clear trend toward lower performance scores but failed to reach statistical significance due to only small differences ( p = 0.055).
In other words, participants who showed a trend in VOT effect in the right direction but failed to reach statistical significance for only one of the two speakers were excluded.