“failed to reach statistical significance”

However, the increase in enzymatic liver function measured by LiMAx failed to reach statistical significance, but showed a positive trend (LiMAx baseline: 402.50 [341.50; 469.80] μg/kg/h vs.

The presence of coronary artery disease (CAD) showed a trend to being a risk factor, but failed to reach statistical significance (OR: 2.22; 95% CI: 0.99–4.95; p = 0.051) in univariate analysis.

We also noted a negative trend between BACE1 protein levels and proteasome activity, but, similar to rodent studies, this trend failed to reach statistical significance ( Fig. 3, K and M ).

In the other cases of poor glycemic control, there was a positive trend but the effect was modest and failed to reach statistical significance.

Additionally, although a slight trend toward poorer stereopsis with increasing anisometropia was observed, it failed to reach statistical significance, indicating high variability among the participants ( Fig. 3 ).

However, the difference failed to reach statistical significance among the younger children, and the difference only approached significance among the older children.

Maintenance BCG instillation showed a trend towards protective effect on recurrence free survival which failed to reach statistical significance ( Table 3 ).

Young adult and aged gbCNP –/– mice had increased blood brain barrier extravasation Young adult gbCNP –/– animals showed a trend to increased permeability in lung, liver, kidney and spleen but this failed to reach statistical significance ( Figures 6A,B ).

Furthermore, the amino acids aspartate, serine, and glycine, which function as important precursors for TCA cycle anaplerosis and nucleotide biosynthesis ( Figure 6—figure supplement 1C ), were also significantly induced by Chlamydia infection, while glutamine showed a trend towards induction that failed to reach statistical significance.

versus 951 ± 16 msec., p < 0.005), whereas the reduced post-contrast T1 times in the HTX patients showed a trend towards being shorter than in controls but failed to reach statistical significance.

Indeed, the Cort.Th and Cort.CSA in the Aln-treated group showed a trend of increase in both genotypes, although the differences failed to reach statistical significance (Figures 5(c) and 5(e) ).

This trial failed to reach statistical significance, however, a clear trend towards improved response rates and prolonged median progression-free survival (mPFS) of combined SSA treatment + VEGF inhibition compared to monotherapy SSA was observed.

Furthermore, the ZOL‐treated groups showed a trend of superior trabecular bone volume compared to that of the low‐dose BE‐treated group, although the differences between the two groups failed to reach statistical significance.

Results exhibited that metastasis, hypoxia, DNA damage, proliferation, apoptosis, and cell cycle showed a trend to be higher in the STAS_positive group but failed to reach statistical significance ( p > 0.05) ( Figure 8A ).

Rosiglitazone Fails to Improve Renal Function Significantly in Moderate I/R Injury In an in vivo model of renal I/R injury caused by an ischemic period of 45 min, treatment with rosiglitazone showed a trend towards improvement of renal functional parameters (GFR, RPF) but failed to reach statistical significance (data not shown).

This is also supported by the observations that HLA-C1 in combination with KIR2DL2, another HLA-C1 receptor, showed no significant association with cerebral malaria, and in HLA-C1 positive individuals, KIR2DL3 positivity showed a trend for association with cerebral malaria ( Table 2 ), although this failed to reach statistical significance (OR = 1.89, 95%CI = 0.82–4.37, P = 0.15).

An increasing trend was noted also in the number of CD4 + T cells stained for TIM3 or LAG3 in tumor of SR59230A, αPD-L1 treatments and their combination, but they failed to reach statistical significance.

The prognostic value of PLR was highly significant in European populations (HR = 1.66) but failed to reach statistical significance in Asian cohorts (HR = 1.28, p=0.12).

Even if the results may have failed to reach statistical significance overall, there was a clear trend toward a lower concentration of acylcarnitine (65% across the whole group) in the patients with recurrence.

qEASL (%) had the same responders based on target lesions and on overall response assessment; it showed a trend but failed to reach statistical significance ( P = .052; Table 6 ).

Lower Zn-NP concentrations showed a trend towards negatively affecting growth for all strains, but this failed to reach statistical significance ( Figure 6 B).

However, all of the three lipofuscin compounds analyzed showed a trend towards higher concentration in aged B6/J +/N and N/N mice compared to age-matched B6/J +/+ controls, although concentrations varied considerably among the elder group while data failed to reach statistical significance.

Interestingly, CSF amyloid β 40 levels showed a trend toward an increase in animals treated with NB-02, however failed to reach statistical significance ( Fig. 3 A ).

Patients with COPD also showed a trend towards higher values (1.1 × 10 5 /mL [0.5–3.3]) but differences failed to reach statistical significance.

ATP turnover showed a trend of decrease in the Ghsr −/− islets pretreated with 22.2 mM glucose but failed to reach statistical significance ( Figure 2 F).