“failed to reach statistical significance”

Many of these associations failed to reach statistical significance, with most studies enlisting traditional null hypothesis significance testing approaches that use the conventional p < .05 level to determine significance.

In the converse causal direction, examining the influence of cognitive function on BMI, all employed MR techniques except for GSMR failed to reach statistical significance (GSMR β = −0.05, P < 0.05), as illustrated in Figure 2 . 3.5 Cross-trait meta-analysis Drawing on genetic correlations and causal outcome effects, there is evidence of a genetic mechanism underlying the relationship between BMI and cognitive function.

Although more patients were alive at the 5-year time point in the group with higher CD1a DC density than the lower CD1a DC group, this failed to reach statistical significance at the P =0.05 level.

Although the interaction of Choline × Sex failed to reach statistical significance, a main effect of Choline on bout length among males during the dark cycle was significant [ F 1,49 = 3.912, p < 0.05], an effect driven by increases in bout length among ethanol‐exposed male subjects [EtOH + Choline > EtOH + Saline, p < 0.05] (Figure 3B ).

In this setting the antagonists WAY100135 and NAN-190 appear to decreased neuronal differentiation but failed to reach statistical significance at p = 0.05.

Weekends failed to reach statistical significance ( P <.05) as a covariate.

Final models were determined using backward elimination technique and terms dropped if they failed to reach statistical significance ( p = 0.05) and when possible, we also used AIC criterion for model fit to the data.

Comparing T0–T1 and T1–T2 observation times, higher mean Δ E 00 and Δ E ab occurred in the first interval T0–T1 but failed to reach statistical significance except in the case of Beautifil which showed significantly higher Δ E ab at T0–T1 after staining in wine ( p < 0.05).

In order to arrive at a more parsimonious model, I gradually eliminated from the full model those predictors that failed to reach statistical significance ( p < 0.05), starting with those that had the highest statistical significance in the initial model.

In zebra finch, the difference in rates between regions containing EBRs and regions without EBRs, although similar in magnitude to that previously reported [ 14 ], failed to reach statistical significance (at P < 0.05).

The increase of Lyso-PAF-AT activity in leukocytes of group A failed to reach statistical significance, but after 45 days this activity was higher compared to that of group B (p < 0.05).

Age (ß = −0.16) emerged as an influential inverse predictor but marginally failed to reach statistical significance at p < .05 ( t = −1.88, p = .064).

Although it failed to reach statistical significance, the data showed a trend for I-LVD to associate with node (N)-stage ( P = 0.052).

Although the time course of left ventricular ejection fraction (LVEF) showed a trend toward reduction in the sham compared to the V-V ECMO group after the end of the experiments, the difference failed to reach statistical significance ( p = 0.053). 2.3.

However, after controlling for age in the model for FSH, BMI failed to reach statistical significance but stayed in the model showing a trend that approached significance ( p = 0.055).

The fourth ANOVA, carried out on the pleasantness scores of the two Sherpa groups tested either at lower or higher altitude, showed a trend toward the consonant effect which failed to reach statistical significance ( F (1, 8) = 3.23, p = 0.056).

The adjusted multivariate analysis failed to reach statistical significance for the primary or the secondary endpoints but showed a trend towards a higher incidence of POCE in patients with eGFR < 60 mL/min/1.73 m 2 , with a HR of 1.56 (95% CI 0.96–2.53; p = 0.071), and towards more frequent unplanned revascularizations (HR 1.91; 95% CI 0.93–3.93; p = 0.078).

Though there was a clear trend for visual field defects in migraine patients, it failed to reach statistical significance (Fisher’s exact P value = 0.073).

While the primary outcome of major cardiovascular events failed to reach statistical significance, a strong trend towards fewer events was noted in the atorvastatin group (6.9 % vs. 9.9 %, p = 0.08).

Comparison between CON and MIA groups using one-way RM-ANOVA failed to reach statistical significance, although BI 409306 treatment showed a trend for attenuation of distance moved following Amph treatment (main effect of groups; F [4,40] = 2.1; P = 0.09; Fig. 1C ).

the ECIC and CNIC) failed to reach statistical significance ( Figure 8 ), we found no evidence for group-wise regional differences within the inferior colliculus: Tests for both the ECIC and CNIC regions reached marginal significance (for each region, F [2,17] >2.73; P<0.10), and showed a similar between-group pattern of manganese uptake ( Figure 8 i.e. control<salicylate; noise≈salicylate).

Although the 0 and ≥3 positive lesions groups showed a trend toward higher rates of clinical pregnancy ( P =0.132), these differences failed to reach statistical significance.

For CV readmission risk, Kaplan–Meier curves showed a decreasing trend that failed to reach statistical significance ( P = 0.287).

Although all large HFpEF trials addressing renin-angiotensin-aldosterone system (RAAS) inhibitors failed to reach statistical significance for the primary outcome, many of them reached borderline significance for a primary endpoint or statistical significance for secondary endpoints, subgroups or post-hoc analyses [ 3 – 5 , 7 , 45 , 46 ].

The plot of predicted slope with 95% confidence intervals versus age at enrollment grouped by smoking status is shown in Fig 5 , which showed a trend of decreased renal function in non-smokers that may be related to their older age, but it failed to reach statistical significance.