“did not reach statistical significance”

In the complete case analysis, long shifts showed a trend toward increased sleep-aid use but did not reach statistical significance (OR 1.64, 95% CI 0.99–2.66) ( Data Supplement 3 ).

Descriptive data showed that treatment-naïve patients receiving RTX experienced no glucocorticoid-related adverse events, whereas relapsed patients exhibiteda statistically significant reduction in steroid dosage and a decreasing trend in relapse frequency after RTX, although the latter did not reach statistical significance.

Compared to the ICL group, the PSS group showed a trend toward reduced microbial diversity; however, this difference did not reach statistical significance (Shannon index: p = 0.065; Simpson index: p = 0.066).

Although differences did not reach statistical significance, parasympathetic activity, as reflected by RMSSD, showed a trend toward higher values during sleep.

There was an increasing trend of MMP activity that did not reach statistical significance with addition of sodium nitroprusside 1 μM or 2 μM combined with hydrogen sulfide 40 μM when compared with the hydrogen sulfide 40 μM control.

29 , 85 In contrast to our findings for DBP, although meta-analysis for SBP showed a clear trend for clinically significant decrease with exercise, it did not reach statistical significance.

In addition, a positive trend was observed when comparing T1 and T3 in APOE-ε4–; however, this association did not reach statistical significance.

Although this result did not reach statistical significance, the point estimate supports the possibility of a positive trend.

The difference between the prednisolone- and placebo-treated groups did not reach statistical significance for the primary outcome (PANSS total score) after 6 weeks, but we observed a statistically significant difference in the PANSS general score and a nonsignificant trend for the PANSS total score at this point.

Radiologic severity, assessed by stricture index (SI), showed a trend toward lower values in the OVB group but did not reach statistical significance (0.41 [IQR 0.38–0.52] vs. 0.52 [IQR 0.42–0.56]; p = 0.063) ( Table 4 ).

Especially for the former result, underscoring that the facilitator’s role notably influences the variability and regularity of the EEG signals, we realized that, specifically, the ‘father’ facilitator was associated with the highest mean entropy (M = 0.684, SE = 0.133), while the ‘mother’ facilitator showed the lowest mean entropy (M = 0.558, SE = 0.133) (please see also Fig 6 ); although pairwise comparisons did not reach statistical significance (in all cases except the close to significance trend of the ‘father’ vs ‘mother’ comparison) after Bonferroni correction (please see Table 4 ).

A positive trend was seen between both 0.2 Hz and 1 Hz thresholds and mediolateral RMSD, however, these associations did not reach statistical significance (0.2 Hz: β = 4.13 p = 0.083, CI −0.57–8.83; 1 Hz: β = 3.12, p = 0.053, CI: −0.045–6.3; Figures 4 , 5 , respectively).

Confirming the latter observation, we detected significant higher frequencies of Cd11b + Ly6G – Lys6C + monocytes in the livers of Tgr5 −/− compared to WT littermates ( Figures 2 E and S2 A), while frequencies of neutrophils (Cd11b + Ly6G + Lys6C − ) in the livers of Tgr5 −/− mice showed a trend toward upregulation but did not reach statistical significance ( Figure S2 B).

Table 2 ), but not the association with the diagnosis; even though EMMs calculated for the factor time*diagnosis showed a trend, they did not reach statistical significance (Supplem.

The data showed a trend towards diminished SSAO activity in the lysates of VAP-1Δ3-co-transfected cells when compared to the control transfected cells, even though the results did not reach statistical significance ( Figure 5C ).

In our analysis, there was a clear trend toward higher all-cause mortality and cardiovascular mortality in patients with lower ADAMTS13 activity in remission, though this did not reach statistical significance, likely because of the relatively small sample size (98 patients with remission ADAMTS13 activity measures) and small number of events.

There is a clear trend toward increased complication rates when thicker ADMs were chosen; however this did not reach statistical significance.

The HFD group exhibited an increasing trend in serum AST and ALT levels, which were reduced by nobiletin supplementation, although the reduction did not reach statistical significance.

The pooled MD for protein oxidation rate showed a trend toward decreasing after LES intake but did not reach statistical significance (MD = −1.20, 95% CI: −4.66–2.27, P = 0.50) ( Figure 11 ).

Although a clear trend toward improved healing in Grade 2-infected wounds compared to Grade 4-infected wounds, the difference in histology scores between the Grade 4-infected wounds (histology score: 2.33 ± 0.58) and Grade 2-infected wounds (histology score: 4.25 ± 1.26) at day 14 did not reach statistical significance ( Figure 6M , p = 0.0857).

A clear trend in the same direction was observed for Overall Survival (15.99 vs 12.1 months), which approached but did not reach statistical significance ( P = 0.0990; Fig. 4I ), likely reflecting the limited statistical power of this smaller cohort.

While the GMV of the left thalamus in patients with dystonia (mean ± SD: 7092.346 ± 816.061) showed a trend towards reduction compared with that in healthy controls (mean ± SD: 7224.300 ± 927.542) ( P uncorrected = 0.011), it did not reach statistical significance after correction for multiple comparisons.

27 , 28 , 29 , 30 In this study, a higher chance of recurrence was demonstrated in patients who exhibited co-localization of PD-1/PD-L1 > 3.3%, although this value did not reach statistical significance; nevertheless, we observed a statistical trend.

In addition, there was a significant trend towards increased SREBP-1c and SCD1 protein levels in the liver; however, this increase did not reach statistical significance.

Notably, hyperdynamic LV function also showed a trend toward higher 30-day mortality than normal cardiac function, although this association did not reach statistical significance.