In males, there was an increasing trend of ALP activity in the Sc + IL4-MSCs group, but this did not reach statistical significance ( P = 0.077) (Fig. 4 A, C).
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“did not reach statistical significance”
In the literature
Although we observed a decreasing trend in the clinical and ongoing pregnancy rates in the normal through obese women, the differences did not reach statistical significance in our study.
There was, however, a weak trend towards increased frequencies and absolute counts of circulating T tm subset in CD4 + T cells in the meth user group but this did not reach statistical significance ( p < 0.1 in both cases).
Similar to a previous post-hoc analysis [ 18 ], the rate of FVC decline of patients in GOLD Stages I + II showed a trend toward being higher than that in GOLD III + IV patients in this substudy, but this did not reach statistical significance.
A Danish randomized controlled trial in which vitamin D3 (1200 IU daily) was administered to patients with CD showed a trend towards lower rates of clinical relapse compared to placebo, although it did not reach statistical significance [ 114 ].
Notably, there was an increasing trend in the proliferative index of PDGFRα − Olig2 + cells (% PDGFRα − Olig2 + Ki67 + /PDGFRα − Olig2 + cells), although it did not reach statistical significance (p = 0.2) ( Figure 2L ).
Although the difference did not reach statistical significance, 28-day survival showed a positive trend in the treatment group also.
In particular PD patients showed higher values of total SD of body sway during OE ( p = 0.005) ( Figure 2 ) and OEC ( p = 0.020) and along the ML axis with OE ( p = 0.019) ( Figure 3 ), while values along the ML axis in the OEC condition showed a trend toward higher values, but the difference did not reach statistical significance ( p = 0.172).
The other three studies showed a trend to higher sensitivity for the 25-gauge needle but did not reach statistical significance [ 138 , 139 , 140 ].
There was also an increasing trend in left ventricular internal diameter during diastole (LVIDd) from 36.2 ± 2.8 mm prior to infarction to 38.7 ± 2.9 mm and 40.9 ± 5.4 mm following infarction and at 8-weeks respectively (Figure 3 b), though this parameter did not reach statistical significance (p = 0.15).
In addition to an increased occurrence of hypertension, patients with the variant allele in IL8 rs1126647A>T showed a trend towards improved PFS/OS (22 vs 14 months for median PFS and 40 vs 25 months for median OS), although the differences between groups did not reach statistical significance.
In the noninfarct area, however, the difference in apoptosis between antagomir and control group hearts only showed a trend towards reduction but did not reach statistical significance ( Figure 4(c) ). qPCR showed that miR-208a silencing in MI also decreased Bax levels at 28 days ( Figure 4(d) ).
At the level of individual vignettes, there was statistical significance for all vignettes except vignette 3, which had a positive trend but did not reach statistical significance.
fT4 was decreased along with a strong trend toward an increase of TRH expression in the PVN that did not reach statistical significance.
Our study showed a trend towards higher IgA levels in the NTG group but this did not reach statistical significance.
It should be noted, however, that serum levels of AST and ALT, both markers of hepatocellular injury, as well as urea, creatinine, and LDH, markers of kidney and systemic organ injury, showed a trend toward lower values in the DNase-treated mice, although this did not reach statistical significance (Table 1 ).
Interestingly, 5 out of 8 patients showed a trend of increasing in Dll4 expression but the difference did not reach statistical significance ( Fig 7C ).
Even though the difference of Cx46 in the suture and nonsuture region did not reach statistical significance, LC-MS/MS analysis also showed a trend consistent with IMS data.
BCR-activated B cells also showed a strong trend for increased MHCII expression after coculture with MCs, although this finding did not reach statistical significance ( Fig. 1h ).
On the other hand, binding of rEgAgB8/2 to macrophages was not observed; the binding index showed a trend to increase in a dose dependent manner, but this trend did not reach statistical significance (Fig. 4a ).
The capsular repair showed a trend toward increasing anteroinferior translational stability compared to the Latarjet procedure, but this did not reach statistical significance.
a small trendgold
In WT mice injected with LpX ( Fig 5A ), a small trend toward increasing UACR values was observed but did not reach statistical significance ( P = 0.106, One Way ANOVA).
Although these associations were nominally significant, they did not reach statistical significance after applying the Bonferroni multiple corrections, potentially due to the limited sample size.
Although BNP levels showed a decreasing trend in the HIIT group, results did not reach statistical significance.
Comparing the diameter of unruptured to ruptured aneurysms, we found a slight trend that did not reach statistical significance towards a greater diameter in the unruptured group compared to the ruptured group.