In a randomized, double-blind study of tocilizumab versus placebo conducted in Japan, although the primary endpoint (time to recurrence) did not reach statistical significance between the treatment groups, there was a favorable trend ( 22 ).
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Survival analysis showed a trend toward decreased overall survival in patients with tumors located in eloquent areas compared to non-eloquent areas, although this difference did not reach statistical significance. 3.5 Correlations Normal distribution was tested using the Kolmogorov-Smirnov test, and age and VtFLAIR were found to be normally distributed ( Fig.
On parallel both groups of male 3xTg-AD mice showed a trend to impaired glucose tolerance albeit it did not reach statistical significance. 3.3.
However, country of birth and oral health satisfaction did not reach statistical significance, and tooth brushing habits was marginally significant in the 2007 cohort.
Although cortisol concentrations during the ACTH test showed a trend towards decrease after seven days, they did not reach statistical significance.
The thrombolysis and in-hospital mortality showed an increasing trend but did not reach statistical significance ( p = 0.07 for thrombolysis, p = 0.10 for mortality).
And the gene expression levels of Cxcl12, Flt1, and Kdr were also significantly increased in the P-EVs group compared with the EVs group ( P < 0.05), while Tgfbr1 also showed an increasing trend, though this did not reach statistical significance (Figure 7 E).
Regarding the TCGA dataset analyses, our results showed a trend, however, the outcomes did not reach statistical significance.
Despite a strong trend towards greater timing adherence with dry powder capsules, the difference between the two study groups did not reach statistical significance.
A positive trend was observed in the attention domain; however, it did not reach statistical significance.
The difference in the number of BM showed a trend toward significance but did not reach statistical significance ( p = 0.086).
Volume in the forceps major and FA in the forceps minor showed a trend toward increase with GA and ADC in the forceps minor showed a trend toward decrease with GA, although these did not reach statistical significance ( p > .082) (Figure 2a ,b) (Table 1 ).
Within the HBV (hepatitis B virus) subgroup, LLR was associated with significantly better OS compared to SBRT ( p = 0.020), and showed a trend toward improved RFS, although the difference did not reach statistical significance ( p = 0.084).
The interval from symptom onset to surgery (OR = 1.073, 95% CI 0.991–1.162, P = 0.084), BMI (OR = 1.472, 95% CI 0.928–2.333, P = 0.100), and more than one preoperative infection episode (OR = 2.049, 95% CI 0.854–4.911, P = 0.107) showed a trend toward association but did not reach statistical significance.
Notably, although the pooled analysis did not reach statistical significance, the meta-analysis showed a numerical trend toward increased risk (OR 1.37) accompanied by very high between-study heterogeneity (I2 = 87.2%).
AAV9-mTERT treated mice also showed a trend for an improved glucose uptake and a better homeostatic model assessment (HOMA (Heikkinen et al, 2007 ; Matthews et al, 1985 )) compared to the AAV9-eGFP controls, although differences did not reach statistical significance (Supporting Information Fig S4D and E ).
Although the 3451 group showed a trend toward increased body weight, the difference did not reach statistical significance ( Fig. 5 A).
PNI-positive samples showed a trend toward higher immune and stromal scores and lower tumor purity compared with PNI-negative samples, although these differences did not reach statistical significance ( Figure 4 D).
After pooling three studies, we found that mHealth interventions showed a near-significant trend toward increasing average daily steps (SMD = 0.57), but the overall effect did not reach statistical significance ( P = 0.07) and exhibited moderate heterogeneity (I2 = 65%).
The RecNciI allele showed a trend toward increased severity (OR = 1.96, 95% CI: 0.96–3.98), but did not reach statistical significance.
Analysis according to overall clinical stage showed a trend toward higher EpAb3-5-assessed EpCAM expression in advanced-stage disease (Stage III-IV) compared with early-stage disease (Stage I-II), but this difference did not reach statistical significance (Figure 2 C).
In contrast, the prevalence of MUO showed a decreasing trend among women in all age groups, although it did not reach statistical significance ( Table 1 ).
For Child-Pugh class B patients, the CCC 2019 criteria also showed a mild trend toward higher OR of 1.11 (95% CI [0.91, 1.34]) however it did not reach statistical significance.
A negative trend was observed between Afamin levels and estimated glomerular filtration rate (eGFR), although it did not reach statistical significance.
Although the θ and α effects during the N1 window did not reach statistical significance, both bands showed a trend toward increased modulation.