“did not reach statistical significance”

25 , 33 Although the <18 years group showed a trend toward higher ADR incidence, the difference did not reach statistical significance, potentially due to the relatively lower prevalence of polypharmacy in this population.

Although the PSM analysis did not reach statistical significance for OS, a clear trend favoring the 2 g/m2 Ara-c dose was observed, suggesting a potential survival benefit with the higher dose in the CLAG regimen for R/R AML.

The TAILOR-PCI trial showed a trend towards reduced ischemic events with genotype-guided therapy versus universal clopidogrel use, although it did not reach statistical significance for the primary composite endpoint of cardiovascular death, myocardial infarction, stroke, stent thrombosis, and recurrent ischemia 186 .

However, patients showed higher systemic inflammatory activity, with elevated CRP levels, whereas ESR showed a trend toward an increase that did not reach statistical significance.

However, when accounting for the total plasma volume obtained by each method (cardiac puncture: ~0.5 mL; perfusate: ~3 mL), total particle yield per animal showed a trend toward higher recovery with perfusate blood collection in both naïve and 50 kdyne SCI groups, though these differences did not reach statistical significance ( Figure 2 c,d). 3.2.

For hs-cTnT, the association between its highest quartile (Q4) and NOAF showed a trend but did not reach statistical significance ( P = 0.056).

Gender showed a trend toward lower odds of failure among males compared to females (OR 0.65, 95% CI: 0.4–1.2), although this did not reach statistical significance ( P = 0.068).

While the primary analysis for superiority showed a trend toward benefit, it did not reach statistical significance.

AS01 B also showed a trend toward greater reactogenicity, though this difference did not reach statistical significance.

Days since hospitalization showed a positive trend but did not reach statistical significance at this stage ( p = 0.081) ( Supplementary Table S4 ).

In the mechanical nociception assay, 18-AG supplementation showed a trend toward the restoration of nociceptive responses to von Frey filament (20.1 mN) in AGPS KO larvae, although this did not reach statistical significance ( p = 0.095 vs.

In our cohort, this score showed a numerical trend toward survival stratification; however, differences in OS and disease control rate (DCR) did not reach statistical significance.

Depressive symptoms showed a positive trend but did not reach statistical significance (PHQ-9 per SD: OR = 1.5, 95% CI 0.9 to 2.5; p = 0.097).

Smoking showed a trend toward a higher prevalence of insomnia, although this did not reach statistical significance.

Although the TT genotype did not reach statistical significance, a clear trend toward increased risk was observed.

Although rh KAI1 treatment showed a trend toward increased muscle mass, these changes did not reach statistical significance when assessed by gross weight measurement.

The study also showed a trend towards a reduction in muscle mass, skeletal muscle mass, lean body mass, bone mineral content and handgrip strength; however, these findings did not reach statistical significance [ 12 ].

Although individual ASA categories did not reach statistical significance, a clear trend toward decreased survival with increasing ASA class was observed ( Table 4 ).

In contrast, Fusobacteriota (CON: 0; CORT: 0.0064 ± 0.0027; CORT + NaBu: 0)exhibited an increasing trend in CORT-treated mice, though this change did not reach statistical significance.

However, the cumulative risk of all-cause death showed a strong trend towards increase but did not reach statistical significance (HR: 1.23; 95% CI: 0.99–1.51; P = 0.052).

Consistently, LPC 18:2 markedly increased Il17a and Il17f mRNA expression and showed a trend toward higher Rorc levels, although the latter did not reach statistical significance ( Fig. 5 E ) .

Female sex showed a trend toward lower mortality risk, though this did not reach statistical significance (adjusted OR 0.70; 95% CI 0.48–1.03; p = 0.073).

In exploratory analyses, the application of intensity‐based data augmentation (random brightness, contrast, and gamma adjustments) showed a trend toward improved segmentation performance on data acquired with an alternate ultrasound device, although this did not reach statistical significance.

29 , 35 Correlation Between Folate and RNFL Thickness In line with these mechanistic insights, we observed a positive trend between folic acid levels and retinal nerve fiber layer (RNFL) thickness in our cohort, although this did not reach statistical significance.

The interaction between SBP level and treatment effect did not reach statistical significance but showed a trend ( P for interaction = 0.150).