Excerpts

A kinase previously not linked to breast cancer subtypes, TESK2, also showed a trend for more frequently harboring an HFI SNP (rs17853159) in TNBC compared to ER+cancers (16% vs 3%, P-unadjusted = 0.06).

(4) In the non-running rats, there was no obvious difference in Col2a1 staining in the PEE group, and the corresponding MOD showed a decreasing trend.

(4) Poisson’s ratio is found to show a decreasing trend as the metallic glass become brittle by annealing, while the shear-to-bulk modulus ratio displays an increasing trend.

An increasing trend was observed for extractable N and for extractable AEM-P a decreasing trend with rehabilitation age ( Fig. 2b–d ).

DMXL2 siRNA treatment caused a decreasing trend but it was variable and not statistically significant ( Fig. 4E ).

Nevertheless, a weak trend was observed towards a concentration of interactions within a few constructs.

Cholesterol esterase buffer did not significantly impact upon the Young’s modulus after 6 months’ of incubation, however, a negative trend in modulus after PBS exposure could be observed for all PU films.

The SEM micrographs do not show a clear trend about the polygon average area enclosed by cracks as a function of Co 2+ content in the plating solution.

In fact, the observed predicted classification can be translated to a highly significant difference between the two groups.

The results showed that the effects of different years, locations, genotypes, location × year, genotype × year, location × genotype, location × genotype × year were all highly significant ( Table 1 ).

A clear trend of the structural preference in different systems was revealed and possible indicators that affect the structure stabilities were introduced.

By in situ hybridization, we detected potent and wide expression of β-arr1 in mature DG and an increasing trend during postnatal development which is similar with other reports 12 35 .

Indeed, conceptually it seems unlikely for phototrophs to occur deep in the mat, however an unexpected trend of increasing cyanobacteria (e.g.

Livestock number, farmland area, road construction, and mean annual temperature were significantly positively related to the change in the area of desertification, accounting for 30.8, 21.9, 4.1, and 14.6% of the total effect, respectively, though the contribution of temperature was only marginally significant.

The enriched GO terms among regulated proteins showed a trend of cytokinesis of the bacteria in the biofilm, when in presence of the organotypic tissue.

Partially significant trends towards moderately decreased ceramide levels and initially increased sphingosine levels (6 h, 18 h), followed by decreased levels, were observed (see Supplementary Table S2 online).

We performed a total of 515 disease susceptibility meta-analysis in all four genetic models, with a total of 86 nominally significant results ( Supplementary Tables 3–6 ).

Multi-centennial length phases of flooding in UK and central Europe correspond with periods of minimum solar irradiance, with a clear trend of increasing flood frequency over the last 1000 years.

From presented results it can be observed that size 3 microspheres showed highly significant performance in comparison to the rest ( Fig. 5b ).

This may have been due to a small sample size (although as p = 0.07 this comparison is approaching significance at the 5% level).

However, the mean number of ECDs in the North Indian Ocean showed a negative trend (~−0.9 days/decade).

In addition, the effect of C1730G was reversed from a protective effect (adjusted OR = 0.18, 95% CI = 0.15–0.22) to a risk effect with borderline significance (adjusted OR = 2.07, 95% CI = 1.02–4.20) after being conditionally adjusted by the other mutations.

Means ± SD were compared using the Student’s t -test according to the following statistical criteria: p < 0.05 = significant; p < 0.01 = highly significant; p < 0.001 = extremely significant.

After adjusting for lifestyle variables and mental health indicators, the associations attenuate slightly for both short sleep (<5.0 hours/day) and longer sleep (≥9.0 hours/day), and the association for short sleep (<5.0 hours/day) become marginally insignificant.

The multiplicative effect modification of gender in 5.0–6.9 hours sleep category for obesity was marginally significant.