In CMS4, aflibercept was associated with an unexpected trend toward poorer OS (median OS: 13.7 vs. 23 months, HR 2.38, 95% CI 1.15 – 4.89, p = 0.016, q = 0.128), and shorter PFS (median PFS: 5.7 vs. 7.9 months, HR 1.48, 95%CI 0.77 – 2.85, p = 0.230).
← all phrases
“an unexpected trend”
Sighted at
p=0.09
In the literature
However, an unexpected trend was the significant increase in surgeries among children under 10 years of age (p=0.042).
This was confirmed by the results of the glmm analysis ( rc = 0.52, 95% CI [0.48, 0.55]) revealing an unexpected trend towards significance of the interaction between type of design error and viewing condition ( F 1, 751 = 3.90, p = 0.048, η p 2 = 0.005, 95% CI [0.000, 0.017]).
For old adults, there was an unexpected trend in the opposite direction, with smiling female [ F (1,82) = 4.22, p < 0.05, η p 2 = 0.05] and male faces [ F (1,82) = 4.91, p < 0.05, η p 2 = 0.06] perceived as younger than neutral faces.
Multivariate regression analysis revealed an unexpected trend toward an inverse correlation between PB basophil counts and NK cell yield from LRSCs ( p = 0.0583; Figure S2 , Table S2 ), suggesting that lower circulating basophil levels may be associated with improved NK cell recovery after plateletpheresis.
In analysis of body weights, we identified an unexpected trend toward a significant genotype × sex interaction in which CRF HcrtR1&R2-KO male mice weighed slightly less than control males ( p = .0595) ( Figure 4B ).
Similarly, no significant association was seen between ICI response and number of CD3 + T cells within the tumor, with an unexpected trend toward higher T-cell infiltration in non-responders (p=0.066).
While not a planned endpoint of the study, this trial also found an unexpected trend for improved median OS in the palliative radiation group (HR 0.56; 95% CI 0.30–1.05; p = 0.068).
26 , 27 In RTOG 0617, dose escalation to 74 Gy compared to 60 Gy resulted in an unexpected trend towards inferior local control 61.8 → 54.3% (p=0.07) and OS 32.1 → 23% (p=0.06). 28 One potential explanation suggests that dose escalation may inhibit the host immune response by reducing populations of lymphocytes. 29 Indeed, Colton et al, and Ladbury et al suggested that the immune system could
There was an unexpected trend for the QTc to be shorter in patients with abnormal troponin levels vs those with normal troponin levels (416 ± 17 ms vs 428 ± 14 ms, P = .08).
However, an unexpected trend toward increased hVps34 activity (37%) was seen in the placebo condition (Fig. 4 A; P = 0.08, condition × time: P = 0.1).
Higher educational attainment displayed an unexpected trend toward lower participation (OR = 0.78, 95% CI: 0.59–1.03; p = 0.083), potentially attributable to coding structure or unmeasured confounding factors.
For our main variables of interest, we found an unexpected trend (on p = 0.09) toward a shorter stay of patients with window view toward man-made objects.
An unexpected trend was observed for jaundice (group difference: − 0.54, P = 0.726) and fever (group difference: − 2.32, P = 0.062), whereby patients with an ECOG score of 0 had higher scores.
However, an unexpected trend is observed whereby the overall Poisson’s ratio approaches −1 as the inner-to-outer diameter approaches 1, although none of the material components possess a Poisson’s ratio lower than −0.5.
An unexpected trend was observed in the tensile strain behavior of the blends.
This increased aggression is associated with decreased daily average temperatures (from ~20°C to ~9°C), decreased mating activity, increased female fecundity, and an unexpected trend toward an increase in female-to-male aggression.
However, we also observed an unexpected trend in which the proportion of genes that are functional was significantly greater for the genes expressed most highly in the ovary than for the genes expressed most highly in other somatic tissues ( fig. 3 A ).
Exposure to compressive forces resulted in an unexpected trend, with accumulation of this ECM protein in the core of both micromasses (Figure 6A -B & Figure S6, 7, 12 ), irrespective of the micromass location in the hydrogel with respect of the actuation membrane.
Recently, an unexpected trend was noted at the Tri-Service General Hospital in Taiwan, where patients diagnosed with IIDs frequently exhibited symptoms of neurodegenerative diseases.
On the other hand, the lid variants demonstrate an unexpected trend.
This theory can be further interrogated in the context of an unexpected trend towards poorer scores for high attending classrooms (i.e., reach).
However, at a 5 μM concentration, an unexpected trend was observed, and none of the analogs exhibited more than 47 % inhibition, except 7l and 7r, which showed 56.84 % and 55.20 % inhibition, respectively.
Authors found an unexpected trend toward higher mortality among non-carrier controls compared with silent carriers stating that further studies are required.
It is worth to notice that U showed an unexpected trend in Velia_T440 compared to bones.