Excerpts

Stratification analysis by gender indicated that the association was marginally significant for males but not for females.

For all samples, rarefaction curves (Supplementary Figure S2 ) showed an increasing trend in trial groups (Group1 to Group 6) over the control group (Group 7), but the difference did not reach statistical significance.

Along with the 185 initial probands with extremely early AAO (n = 94) and extremely late AAO (n = 91), those unrelated schizophrenia patients could be divided into four subgroups (the earliest, earlier, later, and latest AAO) and exhibited an increasing trend of average AAO (Supplementary Figure S2 ).

When 132 patients with an earlier AAO and 158 patients with a later AAO were included, a significant trend in the 14-SNP GRS was detected among those unrelated probands from 4 family groups with the earliest, earlier, later, and latest AAO.

There was extremely significant correlation between diversity index and TOC and AN.

Although RhoA showed a trend towards increased activity following Gc exposure, this was not statistically significant (p value 0.9 at both 3 hour time point and 24 hour time point).

As reported previously in Whitehall, we showed a clear trend of lower sugar intake with higher BMI in men 60 .

By systematically employing our software’s ability to detect and visualize subtle, yet highly significant, regional differences in the fluorescent trace of a muscle-specific mitochondrial marker, we have established a protocol for the discovery of subtle variants in mitochondrial morphology.

Linear regression and correlation analysis indicated that D values had a highly significant negative correlation with most of the selected soil properties.

The possible water activity within the slope streaks covering a large part of the equatorial latitudes is highly significant with respect to the planetary protection policies for future robotic or manned missions to prevent the biological contamination of both Earth and Mars.

Strikingly, only CB0313.1-treated mice exhibited an increasing trend of genus Akkermansia (Fig. 6e ), a known beneficial bacteria in glucose tolerance 6 , 46 .

Collectively, expression of cluster 1 genes in Arntl −/− cells showed a trend toward basal activation and delayed and/or enhanced expression later, at 24 h.

In addition, ER status itself was a significant prognostic factor, with ER-positive status related with 36% (95% CI: 1.06–1.74) higher risk of late all-cause mortality. As shown in Table 5 , a borderline significant modifying effect was observed for ER status in the association between WHR and late all-cause mortality ( P for interaction = 0.087).

However, the Wanxiang and Dayu Cave records, located at a farther inland location in the eastern part of northwestern China do not appear to show a clear trend during this time period (Figs 1 and 3 )—the reason of which deserves further investigation.

Notably, variations in solar irradiance in the last 100 years also display an increasing trend similar to the changes in the tropical SST anomalies (Fig. 4 ).

As expected the binned analysis showed a decreasing trend in activity over time for all groups.

Thus, the present studies also tested the hypothesis that placental accumulation of FM 550 components may be significant and sex specific.

p < 0.05 was considered statistically significant, and p < 0.01 was considered as statistically highly significant.

Although rs11963725 of C2/CFB ( P = 0.0124), rs1054060 of C3 ( P = 0.0454), rs17310296 of CETP ( P = 0.00250), rs4714699 of VEGFA ( P = 0.0368), rs6822976 of CFI ( P = 0.00256), and rs12638651 of ADAMTS9 ( P = 0.00742) showed nominally significant associations, these associations should be interpreted as negative results after permutation tests.

Interestingly, on the 5th day of differentiation (D5), miR-23b maintained an increasing trend whereas miR-23a did not (Fig. 4d ).

BdlC core shows an increasing trend in the Zr/Al record from ~3500 cal yr BP until the end of the Medieval Climate Anomaly (MCA), ~700 cal yr BP.

It shows a highly significant band of correlation with r ≈ 0.6~0.8 from the Philippines Sea to northern SCS.

The curvilinear relationship between masculinity (x-axis) and adiposity (y-axis) explained more variance (F = 24.038, p < 0.0005, R 2 = 0.351) than the curvilinear relationship between adiposity (x-axis) and masculinity (y-axis) (F = 18.934, p < 0.0005, R 2 = 0.301), although both were highly significant.

The effect size for the skin colour-immune response relationship (r = 0.391) was larger than the effect size for the significant masculinity, adiposity-immune response relationship (r = 0.320), indicating that the marginal significance was likely due to the small sample size for skin colour values.

There also was a statistical trend towards a higher abundance of glutathione-s-transferase A2 (q-value = 0.08).