Excerpts

For EPLR, blastocyst quality showed a trend toward lower risk (aOR = 0.49, 95% CI: 0.23–1.10, p = 0.065), though not statistically significant.

The effect modification by PF on FIAs was statistically significant ( P = 0.011), and on RBVs was borderline significant ( P = 0.065).

Based on colony records, the mean body masses of all adult, non-pregnant animals in the WNPRC (438 ± 5 g), and SNPRC (456 ± 7 g) colonies, and the animals maintained on the NEPRC diet but housed at SNPRC (441 ± 7 g) were not significantly different, though the difference between SNPRC and WNPRC approached significance (p = 0.065).

Of our covariate measures, individual differences in Age accounted for a significant portion of the variance in CA1-2 volume ( p = 0.032), and showed a trend for a positive association with CA3-DG ( p = 0.065), whereas Sex accounted for a significant portion of the variance in EC volume ( p = 0.005), reflecting that girls had larger EC than boys.

Increased DA concentrations in Tph2 Δ +/+ at week 6 approached significance compared to week 2 ( p = 0.065), indicating a balancing effect in Tph2 Δ +/+ over time.

The annual health budget showed marginal significance for facility deliveries ( p = 0.065), suggesting a potential resource effect on maternal health service utilisation (Table 6 ).

After also adjusting for diabetes mellitus and total cholesterol (TC), the ability of vegetarianism to decrease the hypertensive risk still nearly reached significance (OR 0.660, CI 0.424–1.026, P = 0.065).

Despite the small size of the ALL sub-cohort of relapsed patients with clinical data available (n = 13), the three patients with mutations showed a trend for shorter OS (HR, hazard ratio 6.4 95% CI 0.89–46.0.8, p = 0.065, Supplementary Fig.

Overall differences across the three groups approached significance ( p = 0.065).

Differences in discrimination performance between treatments approached significance (Friedman’s test: n = 5(8), χ 2 = 14.73, p = 0.065) but subsequent post-hoc analyses (pair-wise Wilcoxon Signed-Rank tests followed by the Bonferroni correction for multiple testing) revealed that discrimination performance in all tasks was statistically indistinguishable (all pairwise comparisons: adjusted p = 1).

For both comparisons by median and in tertiles, differences in body mass index explained a marginally significant part of heterogeneity for the association of mtDNA copy number with overall cancer risk (P = 0.065 and 0.081, respectively).

2 C); whereas carbohydrate oxidation (in g/min) showed a decreasing trend that did not reach statistical significance ( P = 0.065; Fig. 2 D).

A near-significant interaction between group and session was observed (est: 0.95; CI: − 0.06 to 1.96; p = 0.065), indicating that animals who received mecamylamine were trending towards lower reward retrieval in contrast to their ACSF counterparts upon the first several sessions of omission testing.

By χ 2 tests 30 over the 2 × 2 mutation count table regarding three types of non-synonymous sites (See Materials and Methods), we identified the signature of AS which showed statistical significance in DNS variants (P-value = 0.0114), close to significance in INS variants (P-value = 0.0651), and no significance in NNS variants (P-value = 0.2735) (Table 1 ).

After adjustment for clinical covariates, the only bacterial factor associated with increased incidence of treatment failure was the hVISA phenotype (adjusted odds ratio [aOR] 2.420, 95% confidence interval [CI] 0.946–6.191) though with marginal significance ( P = 0.0652).

Western blot analysis further verified lower expression of SDPR in B TM compared to W TM (p < 0.0001) with borderline significance of reduced expression of CAV1 in B TM (p = 0.0654, Fig. 3 c,d), though no racial difference was detected in CAV1 immunohistochemistry staining.

SWISS mice : Femoral aBMD displayed a borderline significant reduction in mice injected with MP at 15 mg/kg/day ( p = 0.0655) and significant reductions in mice injected with MP at 22.5 mg/kg/day ( p = 0.0376) and MP 30 mg/kg/day ( p = 0.0111) compared to control mice (Fig. 4 a).

While showing no interaction between EtOH, brain side, and sex, the ANOVA revealed a significant main effect of embryonic EtOH ( F (2, 24) = 3.719, p = 0.0392), and the post-hoc analysis again showed after 0.1% EtOH an increase in Hcrt neurons that approached significance on the left ( p = 0.0655, ns) but not right ( p = 0.1159, ns) side of the AH in females with no effects occurring in males (Fig. 3 C), as shown in the photomicrographs (Fig. 3 D).

Nevertheless, given the availability of only three RCTs available for subgroup analysis and as well as the moderate effect size regarding the sustained therapeutic effects for inattention (ES: 0.57) with borderline significance ( p = 0.0657), our result was still in favor of a better sustained effect of the combined approach than medication alone, especially for the symptoms of inattention.

At 6-month follow-up, patients with signs of metabolic syndrome showed a trend towards lower PHES compared to patients without these manifestations (− 6.3 ± 1.2 vs. − 3.6 ± 0.6; 95CI = − 0.2–5.6; p = 0.066).

Although larger cumulative stone diameter was a marginally significant factor for SIRS (p = 0.066), it was inversely related to BSI (p = 0.026).

MYC gains showed a trend towards association with negative lymph node status (p = 0.066).

Additionally, two-way repeated measures ANOVA, which was conducted for CBF values between genotypes and time interaction terms, showed that genotypes ( p = 0.012) and time ( p < 0.0001) significantly affected the CBF values, and that the interaction was marginally significant ( p = 0.066).

There was also a marginally significant interaction between Condition, Block, and Group, F (3,114) = 2.47, p < 0.066, η p 2 = 0.06.

The number of female shakes was negatively related to the probability of male courtship in the second sexual encounter (χ 2 = 4.084; p = 0.043), but the number of mounts had only a marginally significant influence (χ 2 = 3.383; p = 0.066).