Excerpts

Gender had no significant interaction with any adverse event except for UTI, where it had a borderline significant interaction (p = 0.05).

Despite a slight trend, there were no statistically significant differences in the measured parameters (Fig. 1E–H , all p > 0.05).

2E , t = 0.79, p > 0.05), but a marginally significant difference in staining density per cell (Fig. 2F , t = 1.38, p = 0.05), suggesting that CB1 mRNA level is higher in VTA glutamatergic neurons than in VTA GABAergic neurons. Δ 9 -THC produces conditioned place aversion in mice We then used the conditioned place preference (CPP) or aversion (CPA) procedures to compare the rewarding or aversive effects of Δ 9 -THC between VgluT2- CB1 ‒/‒ mice and their wildtype control littermates.

SNPs that were identified as being shared loci (GWAS-significant loci for BMI or WHRadjBMI and nominally significant (p < 0.05) for basal or stimulated lipolysis) were used as the exposure.

Given that five exposures and four analysis methods were included in this study, we consider a significant causal effect at the threshold of p < 0.0025 (Bonferroni correction p = 0.05/20) and nominally significant results at p < 0.05.

5a ) while miR-200a was on the cusp of significance (r = 0.43, p = 0.05) (Fig. 5b ).

The CD25 MFI on the Teff cells decreased slightly with marginal significance in the antibody group ( p < 0.05) and increased more than fourfold in the complex group ( p < 0.0001) compared to the control group (Fig. 4 d).

But when we analyzed the treatment duration, we observed that patients who had been treated for a longer time showed a lower percentage of LINE-1 methylation, although the correlation did not reach statistical significance (Spearman’s Rho = −0.329; p = 0.050) (Fig. 2A ).

Although the physical activity, measured in METs, was higher in the high GNRI group, but this difference did not reach statistical significance (P < 0.05) (Table 1 ).

There was a marginally significant effect of Group, F (1, 51) = 4.04, p = 0.05, η p 2 = 0.07 indicating higher proportion of congruent choices in the Deaf (54.2%) compared to normal-hearing participants (51.5%, Fig. 3A ).

For the FCR, the respiratory predictors were marginally significant in the response-aligned ( p < 0.05; see Table 1 ) but not the stimulus-aligned data.

The differences between mean values were considered statistically significant and highly significant at p < 0.05 and p < 0.01, respectively.

Although the difference in DNA damage was not significant, the trained groups showed a trend toward a decrease in spontaneous DNA damage as compared to untrained subjects (P > 0.05).

We found a positive correlation between semantic and image properties that was borderline significant ( r (43) = 0.29, p = 0.050).

If p < 0.05, there was significant difference; if p < 0.01, the difference was extremely significant; if p > 0.05, there was no significant difference.

In contrast, in the S_ st1 vs S_WT comparison, enriched highly significant terms ( p < 0.05) for down-regulated DEGs included “response to water”, “response to inorganic substance”, “response to abiotic stimulus”, “lipoprotein metabolic process”, “lipid transport”, “lipid localization”, “oxidoreduction coenzyme metabolic process”, “NADPH regeneration” and “glycerophospholipid biosynthetic process” (Fig. 5b ).

Survival analysis incorporating low KDM5D as a prognostic indicator yielded nominally significant P -values ( P ≤ 0.05) in seven cancers types, most significantly in head-neck squamous cell carcinoma (n 366, HR 1.79 [95% CI 1.3, 2.5], P = 0.0003) and liver hepatocellular carcinoma (n 249, HR 1.85 [95% CI 1.16, 2.94], P = 0.008).

However, alum and AddaVax differed significantly only at 13 and 16 weeks after primary immunization, although those differences approached significance (0.1 > p > 0.05) at weeks 19–25.

All peaks above the broken line are highly significant (binomial test, p < 0.05).

Additionally, a trend of lower EPA concentrations (p = 0.063) and higher stearic acid levels (p = 0.062) was observed in high NAL compared to low NAL (Table 2 ). On investigating associations between NAL and erythrocyte fatty acids measured, a positive trend between AA concentrations and NAL (β = 0.197, p = 0.050) was observed, while an inverse trend was seen for linoleic acid (β = −0.172, p = 0.088).

While the abundance of Firmicutes did not show a significant correlation with CPP across all treatment groups, there was a strong trend towards a positive linear correlation (Fig. 5 A Top left Spearman r = − 0.34, p = 0.05).

We replicated also the strong influence of embryonic development, kidney transmembrane transporter activity, and kidney and urogenital system morphology in the genesis of CKD from our previous findings 7 : enrichment of all 148 previously identified gene sets was nominally significant (p-value < 0.05).

qPCR analysis at the larval stage between the negative control and days 1, 4 and 7 showed highly significant differences, p < 0.05 (Fig. 4 i).

Importantly, there was no significant interaction between congruency, block and experiment, p = 0.10, and only a marginally significant interaction between RT, block and experiment, χ2 (2) = 6.00, p = 0.050.

During the summer, the average ET a was 329.61 mm, with an increasing trend of 0.43 mm/year ( p < 0.05).