Barely Significant

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highly significantqualifiedgold
The results of this study are highly significant clinically for they demonstrate that adenovirus via subconjunctival injection holds great potential for use in both anterior and posterior ocular disorders, especially those requiring short-term therapy, and that it is a safe form of gene therapy which does not cause liver injury or systemic immune activation.
Comparison of hyperuricemic patients who did not use ULT (HUA /No gout /No ULT), to the matched reference group (No HUA /No gout /No ULT) showed a marginally significant effect on all-cause mortality (adjusted HR 1.24; 95% confidence interval (CI) 0.97–1.59) due to attrition of case number after matching procedure, and a significant risk of hyperuricemia for CVD mortality (adjusted HR 2.13; 95% CI 1.34–3.39) ( Table 2 ).
Additionally, decreases in granulocyte macrophage colony-stimulating factor (GM-CSF; p = 0.07), fractalkine (CX3CL1; p = 0.09), soluble intracellular adhesion molecule-1 (sICAM-1; p = 0.086), vascular endothelial growth factor (VEGF; p = 0.07), and interferon-γ (IFN-γ; p = 0.07) approached significance.