Barely Significant

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showed a trendp = 0.183.6× alpha
Calculating overall survival starting with the first diagnosis of metastasis, patients carrying a B-RAF mutation revealed a trend to a decreased survival compared to patients with wildtype B-RAF (p = 0.052, tissues; p = 0.072, cell lines), whereas patients carrying an N-RAS mutation showed a trend towards a favorable survival compared to patients without N-RAS mutation (p = 0.18, tissues; p = 0.12, cell lines).
showed a trendp = 0.183.6× alpha
The American Society of Parenteral and Enteral Nutrition (ASPEN) recommends avoidance of IEN in high-risk patients based on 2 small RCTs which showed a trend towards higher mortality with IEN (13.9% IEN vs 7.4% CEN; p = 0.18) and increased risk of ventilator association pneumonia with IEN (49.3% IEN vs 30.9% CEN, p=0.02) [ 1 , 7 , 8 ].
approached significancep = 0.1873.7× alpha
However, for aD NDF and aD ADF, particularly stomach type approached significance in both models, and body mass in the model for aD ADF (whole model: R 2 = 0.170, p = 0.187 and R 2 = 0.252, p = 0.074; body mass F = 2.252, p = 0.150 and F = 3.025, p = 0.074; stomach type: F = 3.866, p = 0.064 and F = 3.025, p = 0.074, respectively).
a weak trendp = 0.193.8× alphagold
Even though there was a weak trend for association of the insulin-desensitizing minor A-allele of FNDC5 SNP rs726344 with higher FNDC5 mRNA contents (p = 0.19), this SNP’s MAF was too low to allow a reliable evaluation (only four heterozygous and no homozygous carriers of the minor allele were present among the myotube donors).
showed a trendP = 0.193.8× alpha
Twenty-eight patients with at least minimal response showed a trend toward lower detection rate of MYD88 L265P mutation (25.0% vs. 66.7%, P = 0.19) and mutant allele burden (median, 0.00% vs. 0.22%, P = 0.07), compared to 3 patients less than minimal response.