Barely Significant

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highly significantp<0.051.0× alphaqualifiedgold
Manual forward selection, starting with variables that were more strongly associated with prevalence in univariable analyses, was applied and variables were retained in the multivariable model if p<0.2.The variables that were highly significant (p<0.05) in multivariable meta-regression model were considered as building blocks for interaction terms.
nominally significantp-values < 0.051.0× alphagold
There were less genes indicated from cord blood, peripheral blood or saliva samples collected later in life from twins, therefore GO term analysis indicated only nominally significant processes (with p-values < 0.05 but FDR corrected p-values > 0.1), highlighting phosphatidylinositol 3-kinase/protein kinase B signal transduction, axon guidance and other cell proliferation processes.
marginally significantp = 0.051.0× alphagold
After pleasant picture presentation, a marginally significant decrease of the startle response was observed for val homozygotes dependent on an increase in CTQ scores ( β = −0.51, t = −2.16, p = 0.05), while no associations were observed for val/met ( β = 0.15, t = 0.97, p = 0.34) or met/met genotype carriers ( β = −0.21, t = −1.17, p = 0.25), respectively.