Excerpts

Metabolites approaching significance were noted when 0.05 ≤ q ≤ 0.10.

Three additional sphingomyelin reductions approached significance (q ≤ 0.10).

A marginally significant difference was observed for both Hb in capillary blood using the cyanmethemoglobin method against Hb results of the paired venous blood using the ABX Micros 60 hemocounter, as compared with venous blood using cyanmethemoglobin (β = 0.09, p = 0.09 and β = 0.08, p = 0.059, respectively).

The globalization of food systems is an important trend contributing to nutrition transitions, resulting in the rise of supermarkets and fast food franchises, often in urban centers [ 1 , 18 ].

They projected that the environmental impacts will be highest for Indonesia, with a clear trend for higher consumption of animal source foods (ASF), vegetable oils and fats for all the countries [ 29 ].

[ 79 ] established experimentally that the relationship between glycerophospholipids metabolism and RE activity was highly significant; the abundance change of Dubosiella and Alistipes performs a necessary position in the disorder of lipid metabolism in the process of disease; five pairs of bacterial lipid metabolites manifest the strongest functional correlation with RE.

As shown in Figure 3 , during colonic fermentation, the production of SCFAs was found an increasing trend after 4 h of fermentation and peaked after around 16 h, and then sustained or began decreasing steadily.

Healthful Plant-Based Diet Index Regarding the association between the hPDI and the incidence of asthma symptoms ( Table 3 ), we found a borderline significant inverse total effect (OR (95%CI) per 10 increments of the hPDI = 0.85 (0.73–1.01)) and a significant inverse indirect effect mediated by BMI (OR (95%CI) per 10 increments of the hPDI = 0.94 (0.89–1.00)), with a dose-response relationship (OR (95%CI) = 0.98 (0.95–0.99) for quintile 2 (Q2), 0.96 (0.91–0.98) for quintile 3 (Q3), 0.94 (0.89–0.98) for quintile 4 (Q4), and 0.93 (0.87–0.97) for quintile 5 (Q5) as compared with the first quintile (Q1)).

[ 98 ], based on the NHANES III population, a strong trend was noted in which lower bone mineral density (BMD) as determined by dual energy X-ray absorptiometry (DEXA) was strongly associated with reduced creatinine clearance as estimate by the Cockcroft-Gault (CCr) equation.

plantarum J26, liver function enzymes activities showed a decreasing trend in all groups of mice.

Indeed, the number of products that displayed a FOPNL is continuously evolving, usually with an observed trend towards an increase in the number of labelled products [ 21 , 22 , 49 ].

However, when excluding the prospective cohort study by Stram et al., the inverse association between dietary vitamin E intake and prostate cancer risk attained borderline significance (RR = 0.95; 95% CI = 0.90–1.00; I 2 = 0.04%).

in their metanalysis found a slight trend toward a reduction in CI-AKI despite the larger volume of CM used in patients with STEMI undergoing multivessel revascularization compared to patients who underwent revascularization of the ischemic lesion only.

In contrast, the point estimations of environmental correlations displayed an increasing trend for HbA1c, SBP, and DBP, indicating that the role of environmental contributions is becoming more critical. 4.

Due to the temporal frame provided for structural and functional alterations to proteins involved in excitation-contraction coupling, the impacts of multi-day NO 3 − consumption may be significant for NO bioavailability [ 60 ].

A trend towards reduction in SOL muscle echodensity was observed in AGED mice treated with each formulation ( Figure 2 B, left); a significant reduction was found in GC muscles for mice treated with BCAAs, either alone or plus 2ALA, and a decreasing trend was observed in those treated with BCAAs + Di-ALA ( Figure 2 B, right).

Notably, all formulations exerted a protective effect on SOL muscle force in AGED mice, with an increasing trend in sPtw (R.S.: 20–25%), paralleled by a significant increase in sP0 and by higher tetanus–frequency curves, with a statistically significant difference vs. untreated mice from the frequency of 40Hz onwards ( Figure 4 A–C).

Notably, torque–frequency curves from all AGED cohorts, overlapping at T0 ( Figure 1 C), at T12 showed a trend towards increasing in mice treated with BCAAs + Di-ALA and, to a lesser extent, in those treated with BCAAs + 2ALA, with the R.S. towards ADULT values ranging between 20% and 108% at each frequency ( Figure 1 D).

It is evident from Figure 1 B that with increasing concentrations of Frondoside A (0.35–1 μM), the inhibitory effects on cell migration showed an increasing trend.

Labeling of additives showed a trend of avoiding writing additives with their E-numbers.

The results of the crossover analyses indicated that a maternal supplement of a combination of folic acid and multivitamin (AOR = 0.67, 95% CI = 0.50~0.90), as well as maternal supplement of a combination of folic acid and iron (AOR = 0.70, 95% CI = 0.52~0.96) significantly decreased the risk of obesity in preschoolers born SGA; while only maternal folic acid supplementation during pregnancy decreased the risk of obesity with significance (AOR = 0.73, 95% CI = 0.55~0.97) in the crossover analysis on a combination of folic acid and multivitamin, and marginal significance (AOR = 0.77, 95% CI = 0.57~1.04) in the crossover analysis on a combination of folic acid and iron, respectively.

Predicted biotin biosynthesis was enriched in KO relative to WT mice and was nominally significant, though the q-value did not fall below the alpha of 0.05 following Benjamini-Hochberg correction ( q = 0.0872).

Regarding obesity-related disorders, the presence of type 2 diabetes before surgery was associated with a significant decrease in %TWL in both the univariate and multivariate analyses ( Table 2 ), as well as with a decreasing trend in %EWL ( Table 3 ). 3.3.

Habitual regular cola consumers had a borderline significant age-adjusted association with PanCa mortality (HR: 1.43, 95% CI: 0.99, 2.07) that was attenuated in the multivariable-adjusted model (HR: 1.38, 95% CI: 0.91, 2.07).

Moreover, the BMI showed an increasing trend in all age groups, as shown in Figure 2 .