Barely Significant

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In the stratified analysis of cancer treatment, compared to cancer survivors who did not receive chemotherapy, the associations with mortality among those who received chemotherapy was significantly stronger for SA-Accel (p-interaction = 0.015) and appeared to be stronger for PhenoAgeAccel with a borderline significance (p-interaction = 0.060) (Supplementary Table 9 ).
These tissues were not FDR significant in other traits, but were nominally significant for nonspecific chest pain, overweight, ‘overweight, obesity and other hyperalimentation’, physical activity, smoking, diet intake proportion of protein, and insomnia (SlpFall- difficulty in falling asleep, and SlpWakePM-difficulty in falling asleep after waking up in the middle of the night) ( p < 0.05; Supplementary Data S10 ; Supplementary Fig.
highly significantqualifiedgold
For this, we leveraged statistical fine-mapping in a homogeneous population, stepwise conditional analysis of apparently independent highly significant GWAS lead signals, the exclusion of concealed regional variation through sequencing, and customized functional analyses from matched patient and control samples enriched for protective allele carriers in a recall-by-genotype setting.