Excerpts

In contrast, a recent study with oral administration of Limosilactobacillus reuteri ATCC PTA 6475 to IBS-D patients showed a trend toward reduced serum IL-6 levels compared to the placebo group ( p = 0.052) [ 44 ].

LAWT in the middle, right parts and the mean of all three parts (left, middle, and right) were associated with CE stroke on univariable analysis (OR 1.8; CI: 1.24–2.62, p = 0.002, OR 1.55; CI: 1.08–2.21, p = 0.017 and OR 1.68; CI: 1.05–2.71, p = 0.032, respectively), as well as after adjusting for CHA 2 DS 2 -VASc score and LA diameter in the multivariable regression model (OR 1.94; CI: 1.26–3.0, p = 0.003 and OR 1.57; CI: 1.07–2.31, p = 0.021, respectively), whereas the mean LAWT only showed a borderline significant association (OR 1.66; CI: 1.0–2.75, p = 0.052). 14 out of 56 (25%) CE patients had LAA filling defects in CTA.

It should be pointed out here that this is in disagreement with the fact that ECV showed a trend to be increased in patients with Perugini grade 3 compared to Perugini grade 2 ( p = 0.052).

Bedouin ethnical group was a protective factor for one-year mortality (hazard ratio (HR), 0.68; 95% CI 0.48–0.97), p = 0.034, and a trend for being protective with borderline significance in 30-day mortality (HR, 0.65; 95% CI 0.42–1.004, p = 0.052).

While the IES-R was not associated with hypertension ( p = 0.083), the avoidance and intrusion subscales of IES-R3 as well as the avoidance subscale of IES-R6 were significantly ( p = 0.033, 0.027, 0.035, respectively) associated with hypertension, and its association with IES-R6 hyperarousal was marginally significant ( p = 0.052).

The associations of RBP4 and retinol with the presence of MetS remained close to significance after adjustment for age and sex (retinol: β = 0.223, p = 0.052 and RBP4: β = 0.224, p = 0.051; data not shown).

The results showed a significant decrease in negativity in the More-EYE condition and a marginally significant ( p = 0.052) increase in positivity in the Less-EYE condition ( Table 6 ).

A moderate positive correlation of the Haller index with the MRC-DS dyspnoea scale was demonstrated (r = 0.40), with borderline significance ( p = 0.052).

The graft-to-recipient weight ratio was higher in the ABOi-H group than in the ABOc and ABOi-L groups with borderline significance (1.05 [0.73–1.32] vs. 0.98 [0.60–1.89] and 0.94 [0.70–1.94], p = 0.052). 3.2.

In fact, the mean angular deviation for the surface registration protocol (4.96 ± 3.32o) was larger than the fiducial marker registration protocol (3.38 ± 1.81o), with marginal significance ( p = 0.0526).

In the analysis, according to the use of the LSOM technique, the LSOM group showed a shorter OT than the no-LSOM group, with a marginally significant difference (137.8 ± 61.15 min vs. 148.2 ± 52.67 min, p = 0.0529) (table not shown).

Overall, the difference in OS across all six sites was borderline significant ( p = 0.053) due largely to the small cases of a few sites.

In multivariable analysis, advanced age and prior myocardial infarction independently predicted mortality while treatment with MIDCAB showed a trend toward improved survival ( p = 0.053).

Having three or more metastatic sites showed a trend toward worse OS (HR 2.07, 95% CI 0.99–4.35; p = 0.053), but no covariate reached p < 0.05 in the multivariate model, likely reflecting limited statistical power with 45 patients and 40 events.

This difference was borderline non-significant ( p = 0.053).

Interestingly, the severity of IBD at the time of the second diagnosis almost reached statistical significance ( p = 0.053) in relation to improvement, which might suggest that the timing of the therapy modification in relation to disease severity is crucial.

Night-time declamping was associated with worse 1-year post-transplant patient and graft survival before (HR = 1.44(0.99–2.1); p = 0.058) and borderline significant after adjustment for other predictors (HR= 1.49 (0.99–2.22); p = 0.053), findings which were consistent with the analysis of the entire cohort. 4.

The overall MD was −0.591, with a 95% CI ranging from −1.190 to 0.008 and a marginally nonsignificant result ( p = 0.053) ( Figure 4 ).

A nonsignificant trend toward an increased short-term (2.0% vs. 1.2%, RR: 1.66, 95% CI: 0.99–2.78, p = 0.053) and long-term (4.7% vs. 3.5%, incident rate ratio: 1.40, 95% CI: 0.97–2.03, p = 0.07) all-cause mortality was also found, while no differences were found in long-term (1-year) mortality neither in short- or long-term follow-up for MI, repeat revascularization, stent thrombosis, stroke, major bleeding and the composite of MACEs [ 59 ].

Interestingly, univariate analysis disclosed preoperative RDW as strictly related to disease-free survival ( p = 0.04), but it was not confirmed in the exploratory multivariable analysis where it was however associated to p close to significance ( p = 0.053).

When corrected for LA dilatation ( Supplementary Materials Table S1 ), BMI was a borderline significant predictor of AF inducibility (OR 1.14, p = 0.053).

While the 2279 nm peak showed a nearly significant correlation with proteinuria (ρ = −0.36, p = 0.053), no significant correlations were observed for the other peaks of interest.

After controlling for age, the results reported significant group differences in FBI levels ( F (2,68) = 6.252, p = 0.003, partial η 2 = 0.157); FGW ( F (2,67) = 16,670, p < 0.001, partial η 2 = 0.332) and marginally significant differences in body anxiety ( F (2,67) = 3.077, p = 0.053, partial η 2 = 0.084).

However, Group 1 patients showed a trend toward longer operative times (580.07 ± 126.84 vs. 481.25 ± 119.29 min, p = 0.053), which may reflect the increased technical complexity of operating on previously dissected tissue.

TAPSE/PASP remained significantly associated with a high risk of events using Cox univariate analysis (HR: 0.046; 95% CI [0.004–0.45], p = 0.009) but at the limit of significance in the clinical multivariate model (HR: 0.045; 95% CI [0.001–1.02], p = 0.053).