Barely Significant

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marginally significantp = 0.04991.0× alphagold
tendency toward significancep = 0.122.4× alphagold
Similar results were obtained in the CIMA-CUN cohort ( n = 95 cases); however, in this case, a tendency toward significance ( p = 0.12) for RFS and a marginally significant difference ( p = 0.0499) for OS were observed ( Figure S1A,B, Supplementary Materials ).
borderline significancep = 0.0501.0× alpha
In CMML, ASXL1 and TET2 mutations were associated with a trend toward better prognosis compared with wild-type (HR 0.21, p = 0.052; HR 0.25, p = 0.057, respectively), while U2AF1 mutations were associated with adverse prognosis in univariate analysis with borderline significance (HR 12.20, p = 0.050).
borderline significancep = 0.0501.0× alpha
In these adjusted analyses, the higher prevalence of malignancy in cLP-only patients remained significant compared with oLP-only patients (adjusted OR 2.70, 95% CI 1.45–5.04; p = 0.002) and LPP-only patients (adjusted OR 1.88, 95% CI 1.07–3.31; p = 0.028), with borderline significance compared with gLP-only patients (adjusted OR 2.71, 95% CI 1.00–7.35; p = 0.050).
borderline significantp = 0.051.0× alphagold
This protective effect was particularly pronounced in patients with HFrEF, where OMT compliance was associated with a 38% risk reduction compared with no OMT (HR 0.62, 95% CI 0.39–0.98, p = 0.04), and showed a borderline significant association in HFpEF (HR 0.58, 95% CI 0.34–1.00, p = 0.05), but not in HFmrEF (HR 0.65, 95% CI 0.36–1.15, p = 0.14).
borderline significancep = 0.051.0× alpha
Based on these findings, the null hypothesis—stating that attachment orientation does not affect the rotational accuracy—cannot be fully rejected in the overall model, the findings should be interpreted as indicative of a trend toward improved rotational control with oblique crescent-shaped attachments rather than definitive superiority, given the borderline significance ( p = 0.05) and the moderate effect size (d = 0.5) observed.