Excerpts

In JB6 cells, the administration of 20 μg/mL and 40 μg/mL LQ interventions significantly decreased the level of TNF-α ( p < 0.05) ( Figure 3 D); the administration of 40 μg/mL LQ interventions significantly decreased the level of IL-1β ( p < 0.05) ( Figure 3 E); and the administration of LQ interventions failed to significantly decrease the level of IL-6, but it also followed an increase in dose and showed a decreasing trend ( p > 0.05) ( Figure 3 F). 2.4.

Importantly, the fraction of necrotic cells remained low and did not reach statistical significance ( p < 0.05) under any of the tested conditions ( Supplementary Figures S1 and S2 ), indicating that RA-induced cell death was predominantly apoptotic.

The FW-STI model exhibited a weaker fit ( R 2 = 0.54–0.70) with borderline significance (only W05 reached p < 0.05; p -values of 0.06–0.09 for the remaining samples).

Values of p < 0.01 was considered highly significant and p < 0.05 was considered statistically significant. 5.

Data with p < 0.01 were considered as highly significant, with p < 0.05 considered as statistically significant and with p ≤ 0.1 as marginally significant.

2.2.9) [ 51 ] software (download date: 25 February 2017) Xiaole Shirley Liu, Cambridge, MA, USA) was used to search for highly significant enriched DNA methylation regions with -m 10 100000 , regions with corrected p -value < 0.05 were referred to as DNA methylation peaks.

As shown in Table 5 , a highly significant ( p < 0.05) correlation coefficient (0.85) was found between DPPH scavenging activity and TPC of the extracts, and the correlation coefficient between DPPH scavenging activity and TFC of the extracts was 0.674 ( p < 0.01).

After 48 h, the number of keratinocytes showed an increasing trend only at concentrations of 10 −4 M CeO-NPs-2 (110% of control, p > 0.05); the other samples averaged 79–99% of the control value.

For the rs1800629 TNF-α polymorphism, the GA + AA genotypes showed a significant association ( p = 0.038) with the presence of unfavorable histology and were at the limit of significance ( p = 0.05) with high-risk category and INSS stage 4; however, there were no associations with other prognostic factors ( Table A1 ).

When treated with increasing concentrations of Ang II, miR-34a levels showed a decreasing trend at 24 h treatment but at 48 h and 2 μM concentration its levels augmented (1.63-fold increase, p < 0.05) ( Figure 4 C).

The pairwise equation with control and other groups showed highly significant. p < 0.05 was considered to establish statistically significant differences.

Combined Analysis of Variance Indicating Performance of the Mutant Lines Across the Two Seasons Season and genotype (G) effects were highly significant ( p ≤ 0.05) for all traits except for GH and PL.

While PPRH2 showed a trend toward greater single-agent activity, these differences were statistically significant only when comparing DOTAP to PPRH2 ( p < 0.05) and Sc9 to PPRH2 ( p < 0.01) ( Figure 3 A), indicating that this concentration was appropriately sub-cytotoxic for combination studies.

In addition, of the 154 candidate genes, 83 (54%, including NHLRC1 ) also had a nominally significant gene-wide p < 0.05 in at least one of the other three GWASs and/or the meta-analysis ( Table 1 ).

To note, we do not see a significant change in protein turnover between no recovery and 4 h, and a weakly significant difference between 30 min and 4 h (Dunn ́s, p < 0.05).

The resulting p -values were considered nominally significant at p < 0.05.

GPx did not show any association with AITDs, but selenium showed a borderline significant ( p = 0.05) association with a lower probability of GD: OR 0.98 (95%CI 0.95–1.00).

Compared with the LPS group, the AEE group showed an increasing trend in the content of the Firmicutes ( p > 0.05) and a decreasing trend in the abundance of the Bacteroidetes ( p > 0.05) ( Figure 12 D). 2.11.2.

The differences were judged to be significant and highly significant at * p < 0.05 and ** p < 0.01, respectively. 4.

The FO hybrid showed highly significant differences ( p < 0.05) in RL, FW, and DW as compared with its mid-parent value (MPV) at 21 and 24 DAS ( Figure 1 ).

focused on a SAM-related metabolite methylthioadenosine (MTA) and demonstrated that high MTA levels in plasma were associated with mortality from sepsis, while SAH and SAM approached significance ( p = 0.05 and p = 0.06, respectively) [ 36 ].

From Figure 4 A, it was observed that the degranulation of CAR-HER2-EGFP was highly significant ( p < 0.05) when the cells were cultured in NOIBR and incubated with target cell lines compared to HOIBR, indicating the higher functionality of the constructed CAR-T cells in NOIBR media.

Similarly, the high-dose teak extract group (400–500 mg/dL) exhibited a decreasing trend ( p > 0.05), while the low- and medium-dose teak extract groups (500–600 mg/dL) did not significantly differ from the STZ group ( p > 0.05). 2.3.

Similarly, CS activity was significantly higher in the TS groups compared to the CON group, and significantly higher in the TS2 group compared to the TS4 group, showing an initial increasing trend followed by a decreasing trend with increasing TS duration ( p < 0.05, Figure 4 b).

Statistical significance was accepted at p < 0.05, and differences were considered approaching significance between p = 0.05 and 0.10.