Excerpts

However, it was more markedly significant for the retinas of aged male mice than for the retinas of aged female mice ( p < 0.05 vs.

Clinical evidence, though limited by small sample size and heterogeneity, showed a borderline significant benefit favoring CBD for overall behavioral symptoms ( p = 0.05), agitation, and caregiver distress.

The opposite was also observed in tolerance with an evident trend towards lower K/T ratios and higher STF levels in the tolerant recipients ( p < 0.05 by t -test).

A total of 205 miRNA risk factor associations were found to be nominally significant ( p < 0.05).

The differences were judged to be significant and highly significant at * p < 0.05 and ** p < 0.01, respectively. 4.

Pathway Analysis The proteins expressing a nominally significant difference ( p < 0.05) between the AD and the control groups were investigated using the expression analysis workflow in Ingenuity Pathway Analysis (Qiagen, Venlo, The Netherlands).

This comparison yielded a near-significant strain effect (F (1,44) = 4.01, p = 0.05) with B6J mice directing a greater proportion of their total response towards the active hole ( Figure 2 D), but no sex difference was detected for this variable (sex effect and interactions, p ’s > 0.14).

On the day of oocyte retrieval, an analysis of follicular fluid hormone levels indicated a marginally significant difference in β-hCG concentrations among the eNOS genotypes ( p = 0.050), with the GT group displaying slightly higher mean values than the GG and TT groups.

Apart from the loci mentioned above, numerous other loci were identified that may be significant ( p < 0.05, but higher than the significance threshold currently used for GWAS, which is 5 × 10 −8 ).

The lower dose of LEV showed a trend toward a reduced percentage of animals with seizures compared with that in the TBI-VEH group (50% (5/10) vs. 81% (13/16), p > 0.05).

Regarding correlations with laboratory parameters, we noted a strong significant positive correlation between gal-4 and AST activity (R = 0.42; p < 0.0001) and an almost significant relation with ALT activity (R = 0.25, p = 0.05) ( Figure 2 b).

Endosteal circumference in MPS IIIB mice for males increased by 4.6%, but this did not reach statistical significance and increased by 8.7% in females ( p < 0.05).

Data with p < 0.01 were considered as highly significant, with p < 0.05 considered as statistically significant and with p ≤ 0.1 as marginally significant.

Carlo permutation tests showed that the first and all canonical axes were highly significant ( p < 0.05), suggesting that these physico-chemical parameters played important roles in driving the shifts of the fungal community composition.

Based on PAS staining and calculated sclerosis scores, the development of glomerular sclerosis appeared to be milder in the febuxostat-treated gddY than in the untreated gddY mice, but this difference did not reach statistical significance ( p = 0.05) ( Figure 2 B).

Differences were considered statistically significant or extremely significant when p < 0.05 or <0.01, respectively.

injection of BzATP 60 min later (green arrow), only a nonsignificant trend to increase wind-up activity occurred (# p > 0.05, two-way ANOVA followed by Bonferroni multiple comparisons test, n = 6).

Serum T4 concentration tended to increase, reaching significance in C-PF and near significance in C-Ex ( p = 0.05); no changes were observed in CVS groups ( Figure 6 D–F).

Both nominally significant alterations ( p < 0.05) and those surviving multiple testing correction (FDR < 0.05) were reported; however, only FDR-significant findings were interpreted as robust.

In the SPR experiments, a statistical trend was considered to be statistically significant if its p -value was 1 > p > 0.05.

Nuclear MMP9 expression correlated with ACR and immune cell markers and was borderline significant for AMR ( p ≈ 0.05).

In the HGSOC tissue cohort, the CTNNB1 mRNA was significantly downregulated in FIGO stage IV cases when compared with FIGO stage II or III OC ( p = 0.02), while the FBXW7 change was of borderline significance ( p = 0.05) ( Figure 3 A).

Among smaller, less precise studies toward the bottom of the plot, results were distributed across both significant (light gray area, p < 0.01) and marginally significant regions (dark gray area, 0.01 < p < 0.05), suggesting no evident directional bias.

Statistical significance was accepted at p < 0.05, and differences were considered approaching significance between p = 0.05 and 0.10.

In ET-receptor protein expressions, some effects were detected: thecombined sitaxentan+cinacalcet slightly increased ETB protein ( p = 0.010), while the effects of sitaxentan and cinacalcet alone on ETB protein were of borderline significance ( p = 0.050 and 0.057, respectively).