However, there was a trend toward significance for KIR2DL2 inhibitory receptor in relapse patients (13 relapse patients out of 16 are positive for KIR2DL2) when compared to non-relapse group ( p = 0.069) with a hazard ratio of 3.2 (95% CI: 0.91–11.26) (Table S3 in Supplementary Material).
PWH with CD4+ T count <350 cells/mm 3 at ART initiation had higher IP-10 (p=0·002) and MIG levels (p=0·069, borderline significance) than those with CD4+ T count ≥350 cells/mm 3 .
The maturation stage of TLSs in the IM region showed results consistent with the above findings ( Figure 2J , P =0.069, borderline significance).
The concentrations of growth factor, FGF-2 and cytokines IL-4, IL-5, IL-15 and TNF-α were also found to be significantly higher ( p < 0.05 or close to significance, p = 0.0699, for IL-17A) after vaccination in the adult group.
No differences were observed among the groups after 8 weeks of treatment; however, memory Tregs showed a strong trend toward increased activation (HLA-DR + CD194 + ) in the L. johnsonii N6.2 treatment group after the washout period ( p = 0.07) (Table S5 in Supplementary Material).
On the other hand, Parabacteroides was significantly under-represented in RRMS patients ( p = 0.003), who also showed a reduction in [ Ruminococcus ] and Lachnospira ( p ≤ 0.0008), a marked increase in Streptococcus ( p = 0.006), and an increasing trend for [ Eubacterium ] ( p = 0.07).
Neutrophils showed a trend to increase in ELA groups (P < 0.07) ( Figure 10C ).
The difference in PFS benefits across treatment line subgroups was observed as a near-significant trend (P = 0.070) ( Figure 2B ). 3.3.
ASAL showed a trend (i.e., close to statistical significance; p = 0.07; Figure 8R ) towards ctsb down-regulation, which resulted in significantly lower mRNA levels in ASAL/no lice salmon than lice-infected salmon ( Figure 8H ).
Defined by methodology A, B, or C, higher PD-L1 group showed a better prognosis trend although the difference was marginally significant as determined by the log-rank test (p=0.07 as classified by methodology A, p=0.14 as classified by methodology B, p=0.12 as classified by methodology C, Figures 1A–C ).
However, controllers had a strong trend of higher proportions of CCR5-expressing CD8+ T cells in comparison to HCs ( P =0.07, Figure 1D ).
About other miRNAs, miR-30a showed an interesting trend resulting higher in NR vs R (p=0.07); instead, there were no statistically significant differences in miR-21, miR-22, miR-34a, miR-125b, miR-150 and miR-155 expression between two patient groups ( Supplementary Figure S6 ).
It was revealed that in the group of parturient women, the age distribution of seropositive and seronegative women differed—29 (25, 33) years and 27 (25, 32) years, respectively (p = 0.07 borderline significant).
The result was almost significant in MR-PRESSO model (OR[95%CI] = 1.08 [1.01, 1.16], p =0.07) ( Figure 3A ).
PLA signal of HA specimens differed from deep DA (p< 0.001), while luminal DA regions only expressed a statistical trend (p=0.07) ( Figure 3H ). 3.5.
A significantly larger proportion of total CD4 + and CD4 + T EMRA cells in SAT from diabetics were CD57 + CD69 lo CX 3 CR1 + GPR56 + compared to SAT from non-diabetics ( p = 0.051), and approached significance for CD4 + T EM cells ( p = 0.07) ( Figure 5C ).
As expected, a higher number of DSA had borderline significance with a higher number of HLA mismatches ( p -value = 0.07, HLA antigen data).
Faecalibacterium showed significant negative correlations with DAS28-CRP (ρ= -0.37, P = 0.044) and a strong trend with DAS28-ESR (ρ=-0.34, P = 0.070).
Consistently, both antibodies elevated ADPR production in MM cells, with DARA reaching statistical significance (p = 0.03) and ISA showing a near-significant trend (p = 0.07).
Patients whose TTVL 3-months post-transplant exceeded the currently proposed cutoff to predict infections within the first year post-transplant [6.2 log 10 ] showed a trend towards a higher risk of being hospitalized with an infection in the following 9 months, albeit without being statistically significant (HR=1.642, P =0.07).
Renal disease is a major predictor of damage progression in SLE, and our findings of a near-significant association of IL-18 with organ damage in multivariable analysis ( p = 0.07) are supported by previous findings in a smaller study which reported increased serum IL-18 in SLE patients with organ damage ( 53 ).
The transcript levels of tnnt2 showed a trend of upregulation in GS2 compared with GS0 individuals (p=0.07).
The results for the training cohort showed marginal significance for CCR7 (p = 0.07) and significance for SPP1 (p = 0.0033), while in the testing cohort, significance was observed for CCR7 (p = 0.035) and marginal significance for SPP1 (p = 0.073) ( Figure 6F ).
Of note, the expression of STAT3 in M-MDSC of CoV2+ when compared to CoV2- participants approached significance (0.4 ± 0.3 vs 15.9 ± 10.6; p=0.07).
Patients with UC also had a trend toward lower luciferase activity than control patients, but this just failed to reach statistical significance ( p = 0.070).