Excerpts

In 2 trials (MLSPZV1 (Mali 1) (Mali, 2014) and MLSPZV2 (Mali 2) (Mali, 2016)), antibody levels were significantly higher in protected vs unprotected males and in one additional trial (EGSPZV3 (Equatorial Guinea, 2018)) the difference was borderline significant (p=0.059).

Although the prevalence was higher in T1D, this did not reach significance ( p = 0.2069), but approached significance in males ( p = 0.0593).

Although patients with higher free AIM concentrations on day 1 showed a trend toward improved 30-day survival (p = 0.0595), statistical significance was not reached until day 8.

Although there was a significant increase in annexin-V-expressing HSA+ cells that were treated with birinapant and MG1 in comparison to cells treated with birinapant alone, this increase in annexin V+ cells did not quite reach significance ( p = 0.0596) ( Figure 5C ) when compared with the cells only treated with MG1.

Total alveolar nuclear counts were observed to be elevated in WT mice exposed to DE compared to WT mice exposed to saline (p=0.0377), with an observed trend of increased nuclei in KO mice exposed to DE compared to KO mice exposed to saline (p=0.0598) ( Figure 4H ).

However, in the under 30-year age group, the G-allele of rs6478108 showed a strong trend toward association with T1R (OR = 2.08, p = 0.06; Table 2 ; Figure 2 ).

Increased secretion of IFN-γ and TNF-α in PMA+I stimulated MoDC approached significance (P = 0.06 and P = 0.05, respectively).

At the metabolic level ( Figure 6A ), plasma IFNγ concentrations showed a trend toward a positive correlation with the KYN/TRP ratio (ρ = 0.40, P = 0.06) and, more strikingly, with the QA/KA ratio (ρ = 0.77, P < 0.001), demonstrating that systemic inflammation is tightly associated with a cortical metabolic profile favoring excitotoxic outputs.

Validation in SLE, RA, IBD, and JIA By comparing the TPM values of CD160 and CD58 from four RNA-seq datasets including SLE ( GSE112087 ), RA ( GSE117769 ), IBD (GSE112057IBD), and JIA (GSE112057JIA), we found that the aberrant expression of CD160 was statistically significant in SLE ( P = 0.0006), IBD ( P < 0.0001) and JIA ( P = 0.0005), and was marginally significant in RA ( P = 0.06) ( Figure 3 ).

Also, two factors, number of relapses and CRS grade, were shown to have significant relations to MRD-negative CR ( p < 0.05, Tables 2 , 3 ), while the relation between CRS grade and CR was marginally significant ( p = 0.06, Table 3 ).

There was a nearly significant positive association between IAA and percent NK T-cells (adjusted p = 0.06) and a non-significant association of similar magnitude (based on the beta coefficient) for indole ( Figure 2B ).

Only LV showed a trend towards significance (AUC = 0.602; p = 0.060).

In the peritumoral area, higher frequencies of CD3 + or CD8 + T cells were linked to significantly longer DFS (p=0.0097), while an increased density of PD-1 + CD8 + T cells showed a strong trend towards a positive impact on DFS (p=0.06) ( Figure 5B ).

Second, the retrospective design and hospital-based case selection may limit the robustness of certain findings—for instance, the association between lactation duration and PRL levels showed borderline significance (P=0.06).

Induction of IFN-λ3 upon MERS-CoV-nsp2 expression was near significance (p=0.06) ( Figure 1D ); whereby IFN-λ3 was not impacted by MERS-CoV-nsp5 ( Figure 1D ).

Notably, even patients who did not undergo transplantation showed a trend toward improved 4-year OS (21% vs. 16%, P = 0.06) ( 4 ).

Difference between these two subgroups was close to significance (Chi2 = 3.41, df = 1 (P = 0.06), I2 = 70.7%).

Furthermore, the RNA expression of SRC was positively correlated with the protein expression (r = 0.67, p < 0.001) ( Figure 6P ), and the RNA expression of HSP90AA1 was positively correlated with the protein expression, and the statistical significance approached significant (r = 0.35, p = 0.06) ( Figure 6N ).

Compared to IVIG, GTX showed a reduction in all-cause mortality, which was borderline significant (p=0.06).

Associations between NR3C1 DNA methylation and peritraumatic distress, perceived stress, and depression Results in the lower panel of Table 2 show that pregnant women who were depressed had a higher NR3C1 DNA methylation level than women who were not depressed with a marginal significance level (t = −2.13, p = 0.06).

While SBP and DBP did not correlate with triglyceride levels or age, we did observe a moderate, borderline significant negative correlation ( P = 0.06) between male sex and SBP but not DBP, indicating that systolic blood pressure of female CAD patients tended to be higher in our cohort.

Borderline significance of sTNFRSF3 (p=0.06) were demonstrated, Figure 2 .

salmonis infection since ctsb was negatively correlated with total lice counts, while emc10 showed a similar trend (i.e., almost significantly correlated; p = 0.06).

Compared to MN, they showed comparatively lower 24-hour proteinuria excretion but with marginal significance (3.96 versus 4.63 g/d, P =0.060) and presented significantly less frequency of nephrotic syndrome (47.45% versus 72%, P <0.001).

Semiquantitative analysis indicated that the CD11b + macrophage population was higher in the UUO KLN than the contralateral KLN; although the comparison did not quite reach significance (p=0.06) at Day 7, a significant increase (p<0.01) was observed at Day 14 ( Figure 2B ).